Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 27, 2026, 8:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Parkinson's Disease, Dysarthria
Interventions
SpeechEasy Model ITC
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Quadriplegia/Tetraplegia, Tetraplegic; Paralysis, Stroke
Interventions
N1 Implant, R1 Robot
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Completed No phase listed Observational Accepts healthy volunteers

A Multidimensional Study on Articulation Deficits in Parkinsons Disease

NCT05754086
Conditions
Parkinson Disease, Dysarthria, Hypokinetic
Interventions
Clear Speech, Less Clear Speech
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Amyotrophic Lateral Sclerosis, Parkinson Disease
Interventions
Phonetic complexity effects on speech motor performance
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
19 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Fairway, Kansas • Columbia, Missouri
Terminated No phase listed Observational Accepts healthy volunteers

Central Mechanisms in Speech Motor Control Studied With H215O PET

NCT00001308
Conditions
Communication Disorder, Healthy, Stuttering, Tourette Syndrome, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
1,163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Dysarthria, Hypokinetic
Interventions
Listener Training
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Tallahassee, Florida • Logan, Utah
Completed Not applicable Interventional Accepts healthy volunteers

Age-related Correlates of Treatment for Late-acquired Sounds

NCT03663972
Conditions
Speech Sound Disorder, Phonology Disorder, Phonology Impairment, Phonological Disorder, Articulation Disorders in Children, Developmental Phonological Disorder, Speech Disorders, Speech Delay, Articulation Disorders, Developmental
Interventions
articulation therapy, phonologic treatment
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
4 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Not listed Not applicable Interventional Accepts healthy volunteers

Detecting Parkinson's Disease Through Speech Analysis

NCT03133611
Conditions
Parkinson Disease, REM Sleep Behavior Disorder
Interventions
Speech assessment, Routine clinical assessment
Other
Lead sponsor
Czech Technical University in Prague
Other
Eligibility
50 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers Results available

Application of Ideal Binary Masking to Disordered Speech

NCT05244603
Conditions
Hearing Loss, Sensorineural, Dysarthria
Interventions
Ideal binary mask
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 90 Years
Enrollment
435 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Logan, Utah
Conditions
ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis
Interventions
Isometric Lingual Strength Exercises
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Davie, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Pediatric Speech Therapy Session Frequency and Speech Outcomes

NCT05900180
Conditions
Speech Therapy, Language Disorders in Children, Articulation Disorders in Children, Communication Disorder, Childhood, Pediatric, Mode of Therapy, Frequency of Therapy
Interventions
Speech Therapy
Behavioral
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
18 Months to 16 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked in Syndrome, Muscular Dystrophies
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Stanford, California • Boston, Massachusetts
Conditions
Dysarthria, Down Syndrome
Interventions
Speech sessions
Behavioral
Lead sponsor
Duke University
Other
Eligibility
8 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Parkinson Disease, Atypical Parkinsonism
Interventions
Behavioral speech strategies + speech amplification
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
East Lansing, Michigan
Completed No phase listed Observational Accepts healthy volunteers

Study of Brain Activity During Speech Production and Speech Perception

NCT00004991
Conditions
Developmental Articulation Disorder, Stuttering
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
6 Years to 65 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Speech Sound Disorder
Interventions
Motor-based speech treatment
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
7 Years to 11 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Syracuse, New York
Conditions
Articulation Disorder, Dysarthria, Prelingual Deafness
Interventions
Opti-Speech
Device
Lead sponsor
Vulintus, Inc.
Industry
Eligibility
12 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Cleveland, Ohio • Richardson, Texas
Active, not recruiting Not applicable Interventional

Dysarthria Management for Minor Groups

NCT06593860
Conditions
Parkinson Disease, Dysarthria
Interventions
Remote speech rehabilitation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
25 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Parkinson's Disease
Interventions
Combined speech and exercise intervention, Health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Intelligibility Assessment for Parkinson's Disease

NCT04829006
Conditions
Parkinson Disease
Interventions
Understand Me For Life
Device
Lead sponsor
Long Island University
Other
Eligibility
30 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Brooklyn, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Cerebellum in Speech

NCT03972202
Conditions
Cerebellar Ataxia, Dysarthria, Healthy
Interventions
MRI, TMS, Speech-motor behavioral testing
Diagnostic Test · Device · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
3
States / cities
Berkeley, California • San Francisco, California • Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Voice Treatment for Parkinson's Disease

NCT00123084
Conditions
Parkinson's Disease, Dysphagia, Dysarthria
Interventions
Voice/Respiration Treatment, Speech/Articulation Treatment
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
45 Years to 85 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2012
U.S. locations
2
States / cities
Denver, Colorado • San Antonio, Texas
Conditions
Dysarthria, Intelligibility, Speech
Interventions
Perceptual Training
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 80 Years
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Tallahassee, Florida • Logan, Utah