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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Phonology Impairment Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

NCT05741853
View directory record Official record
Conditions
Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia
Interventions
Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT)
Behavioral
Lead sponsor
Stephanie Grasso
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional Results available

An RCT of a Telemedicine Intervention for Hypokinetic Dysarthria in PD

NCT04617496
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Combined speech and exercise intervention, Health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intelligibility Assessment for Parkinson's Disease

NCT04829006
View directory record Official record
Conditions
Parkinson Disease
Interventions
Understand Me For Life
Device
Lead sponsor
Long Island University
Other
Eligibility
30 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Application of Ideal Binary Masking to Disordered Speech

NCT05244603
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Dysarthria
Interventions
Ideal binary mask
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 90 Years
Enrollment
435 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

BiOfeedback, Online for Sibilant Treatment

NCT07041723
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Visual-acoustic biofeedback for Sibilants
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
8 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomfield, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

Voiceitt for People With Impairments in Speech

NCT06874322
View directory record Official record
Conditions
Speech Impairment, Speech Disorder
Interventions
Voiceitt
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional

Intensive Dysarthria Sessions in Adults and Children With Down Syndrome

NCT01684670
View directory record Official record
Conditions
Dysarthria, Down Syndrome
Interventions
Speech sessions
Behavioral
Lead sponsor
Duke University
Other
Eligibility
8 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

NCT06094205
View directory record Official record
Conditions
Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked-in Syndrome, Muscular Dystrophies
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

Tongue-strengthening Exercises in People With ALS.

NCT07295990
View directory record Official record
Conditions
ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis
Interventions
Isometric Lingual Strength Exercises
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 23, 2026, 6:23 AM EDT
Not listed No phase listed Observational

Subthalamic Nucleus Deep Brain Stimulation in Speech Study

NCT05493670
View directory record Official record
Conditions
Parkinson Disease, Dysarthria
Interventions
Not listed
Lead sponsor
Jeremy Greenlee
Other
Eligibility
21 Years to 84 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Perceptual Training to Improve Listeners' Ability to Understand Speech Produced by Individuals With Dysarthria

NCT04897711
View directory record Official record
Conditions
Dysarthria, Intelligibility, Speech
Interventions
Perceptual Training
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 80 Years
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Tallahassee, Florida • Logan, Utah
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

Speech Amplification Devices for Parkinson Disease: Talker- and Technology-Driven Enhancements

NCT07599696
View directory record Official record
Conditions
Parkinson Disease, Atypical Parkinsonism
Interventions
Behavioral speech strategies + speech amplification
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 23, 2026, 6:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Brain Activity During Speech Production and Speech Perception

NCT00004991
View directory record Official record
Conditions
Developmental Articulation Disorder, Stuttering
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
6 Years to 65 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 23, 2026, 6:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Detecting Parkinson's Disease Through Speech Analysis

NCT03133611
View directory record Official record
Conditions
Parkinson Disease, REM Sleep Behavior Disorder
Interventions
Speech assessment, Routine clinical assessment
Other
Lead sponsor
Czech Technical University in Prague
Other
Eligibility
50 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Age-related Correlates of Treatment for Late-acquired Sounds

NCT03663972
View directory record Official record
Conditions
Speech Sound Disorder, Phonology Disorder, Phonology Impairment, Phonological Disorder, Articulation Disorders in Children, Developmental Phonological Disorder, Speech Disorders, Speech Delay, Articulation Disorders, Developmental
Interventions
articulation therapy, phonologic treatment
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
4 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Jul 23, 2026, 6:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Evaluation of Tongue Movements in Speech and Swallowing

NCT00001167
View directory record Official record
Conditions
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis, Speech Disorder
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
570 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1979 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional

Evaluating the Efficacy of Opti-Speech for Speech Treatment

NCT02705326
View directory record Official record
Conditions
Articulation Disorder, Dysarthria, Prelingual Deafness
Interventions
Opti-Speech
Device
Lead sponsor
Vulintus, Inc.
Industry
Eligibility
12 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Cleveland, Ohio • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Dec 30, 2018 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Voice Treatment for Parkinson's Disease

NCT00123084
View directory record Official record
Conditions
Parkinson's Disease, Dysphagia, Dysarthria
Interventions
Voice/Respiration Treatment, Speech/Articulation Treatment
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
45 Years to 85 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2012
U.S. locations
2
States / cities
Denver, Colorado • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Jul 23, 2026, 6:23 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Cerebellum in Speech

NCT03972202
View directory record Official record
Conditions
Cerebellar Ataxia, Dysarthria, Healthy
Interventions
MRI, TMS, Speech-motor behavioral testing
Diagnostic Test · Device · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
3
States / cities
Berkeley, California • San Francisco, California • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Jul 23, 2026, 6:23 AM EDT
Completed No phase listed Observational

Screening in Oculopharyngeal Muscular Dystrophy

NCT02877784
View directory record Official record
Conditions
Oculopharyngeal Muscular Dystrophy
Interventions
Videofluoroscopic swallowing study, Functional Oral Intake Scale, Eating Assessment Tool-10
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Not applicable Interventional

Emotional Prosody Treatment in Parkinson's

NCT01956266
View directory record Official record
Conditions
Parkinson Disease
Interventions
Emotional prosodic treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

Treatment for /s/ Production Errors in Children With Speech Sound Errors

NCT07214480
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Motor-based speech treatment
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
7 Years to 11 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 23, 2026, 6:23 AM EDT
Recruiting Not applicable Interventional

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

NCT05724173
View directory record Official record
Conditions
Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked in Syndrome, Muscular Dystrophies
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Stanford, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 23, 2026, 6:23 AM EDT
Completed Phase 1 Interventional

Improve Speech Using an In-the-ear Device in Parkinson's Disease

NCT00488657
View directory record Official record
Conditions
Parkinson's Disease, Dysarthria
Interventions
SpeechEasy Model ITC
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Jul 23, 2026, 6:23 AM EDT