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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Physiological Responses Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response

NCT02372110
View directory record Official record
Conditions
Anxiety
Interventions
HPA, ANS stimulation, Placebo
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 22, 2026, 7:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

NCT05217589
View directory record Official record
Conditions
Other Gastrointestinal Disorders, Cramp, Abdominal
Interventions
Funny/Amusing Video Clips, Horror/Scary Video Clips, Thrilling/Suspenseful Video Clips
Other
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 22, 2026, 7:32 AM EDT
Completed No phase listed Observational

Functional and Physiological Responses to Lokomat Therapy (Pilot Study)

NCT00883142
View directory record Official record
Conditions
Spinal Cord Injuries, Multiple Sclerosis, Stroke
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced Sep 22, 2026, 7:32 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Human Behaviors Related to the Expectation of Pain

NCT03739645
View directory record Official record
Conditions
Fear Pain
Interventions
Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 88 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Sep 22, 2026, 7:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Receptors in Sympathetic Nervous System Regulation

NCT00029627
View directory record Official record
Conditions
Healthy
Interventions
Yohimbine
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 22, 2026, 7:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sitting Interruption and Whole-body Cardiovascular Health

NCT05316571
View directory record Official record
Conditions
Sedentary Behavior, Sedentary Time
Interventions
One 5-Minute Walking Bout Each Hour, One 15-Minute Standing Bout Each Hour, One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour, Uninterrupted Sitting
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
30 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 22, 2026, 7:32 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study

NCT02860975
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Inhaled Nitrogen
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 22, 2026, 7:32 AM EDT
Completed No phase listed Observational

Genetic Causes of Panic Disorder

NCT00083265
View directory record Official record
Conditions
Panic Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 60 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Sep 22, 2026, 7:32 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Perception of Physical Exertion in Healthy Weight and Obese Adolescents

NCT01695785
View directory record Official record
Conditions
Physiological Response to Exercise, Perception of Exercise Difficulty
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
13 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 9, 2015 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Fiber on Appetite and Digestion Hormones

NCT01050101
View directory record Official record
Conditions
Psychological Phenomena and Processes, Nutrition Physiological Phenomena
Interventions
No fiber, Low GI high fiber viscous meal, Low GI high fiber non-viscous
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Phase 3 Interventional

Depression Related Improvement With Vardenafil for Erectile Response

NCT00661219
View directory record Official record
Conditions
Erectile Dysfunction, Depression
Interventions
Levitra (Vardenafil, BAY38-9456), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older · Male only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
15
States / cities
Huntsville, Alabama • Anchorage, Alaska • Beverly Hills, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Race, Natriuretic Peptides and Physiological Perturbations

NCT03070184
View directory record Official record
Conditions
Healthy, Pre Hypertension
Interventions
Exercise capacity VO2 max determination, Standardized meals, Exercise challenge, Metoprolol Succinate ER
Other · Dietary Supplement · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Phase 2 Interventional

Neoadjuvant Chemotherapy Using Doxorubicin and Paclitaxel in Treating Women With Large Breast Cancer

NCT00096291
View directory record Official record
Conditions
Breast Cancer
Interventions
Doxorubicin followed by Paclitaxel, Paclitaxel followed by Doxorubicin
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Sep 22, 2026, 7:32 AM EDT
Withdrawn Phase 4 Interventional

Placebo Controlled Evaluation of Sedation and Physiological Response to Intranasal Dexmedetomidine in Severe COPD

NCT02773797
View directory record Official record
Conditions
COPD
Interventions
IN-DEX 1.0 mcg/kg, intranasal saline, IN-DEX 1.5 mcg/kg, intranasal saline, Placebo - Saline
Drug
Lead sponsor
Dayton VA Medical Center
Federal
Eligibility
45 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Sep 22, 2026, 7:32 AM EDT
Withdrawn Not applicable Interventional

Intradural Percutaneous Stimulation

NCT03380104
View directory record Official record
Conditions
Pain, Chronic
Interventions
Intradural Spinal Cord Stimulation, Administration of Questionnaires
Device · Behavioral
Lead sponsor
Matthew Howard
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TDSM- Testosterone Dose Response in Surgically Menopausal Women

NCT00494208
View directory record Official record
Conditions
Hysterectomy, Ovariectomy, Menopause, Testosterone Deficiency
Interventions
Testosterone
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
21 Years to 60 Years · Female only
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Sep 22, 2026, 7:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biochemical and Physiological Changes Associated With Differing Durations of Relaxation Response Training

NCT00636129
View directory record Official record
Conditions
Stress
Interventions
Relaxation Response + Stress Management Curriculum
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 49 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2011 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response

NCT00355797
View directory record Official record
Conditions
Bradycardia
Interventions
Closed Loop Stimulation (CLS), Standard Rate Adaptive (R) Technology, Non-rate adaptive (DDD) pacing
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,491 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
99
States / cities
Albertville, Alabama • Gadsden, Alabama • Jasper, Alabama + 82 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2012 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Phase 1 Interventional

Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products

NCT04226690
View directory record Official record
Conditions
Pain
Interventions
Active CBD/THC Dose 1, Active CBD/THC Dose 2, matched placebo comparator
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 68 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Results available

A Comparative Study Between AirSeal, an Integrated Insufflation System, and Conventional Insufflation

NCT02075658
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
AirSeal® System-Interventional, Conventional Insufflator and Trocar
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of the Q-Collar During High-Intensity Cycling Exercise

NCT07808710
View directory record Official record
Conditions
Physiological Responses to High-Intensity Exercise
Interventions
Q-Collar™
Device
Lead sponsor
University of Northern Iowa
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Cedar Falls, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Responses to Varying Environments in Virtual Reality Simulations

NCT04465240
View directory record Official record
Conditions
Residential Characteristics, Emotions, Stress, Psychological, Stress, Physiological
Interventions
Virtual reality
Other
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Emotional Arousal in Food Preference and Taste

NCT02402088
View directory record Official record
Conditions
Obesity, Food Craving, Food Consumption
Interventions
Stress Imagery, Food Cue Imagery, Neutral-Relaxing
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Sep 22, 2026, 7:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study to Examine the Acute Impact of Veillonella Supplementation on Exercise and Lactate Responses

NCT05816291
View directory record Official record
Conditions
Lactate Blood Increase, Exhaustion - Physiological
Interventions
Time to Exhaustion at velocity at VO2max
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 50 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 22, 2026, 7:32 AM EDT