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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Physiological Responses Clear all
Completed No phase listed Observational Accepts healthy volunteers

Physiological Responses in Tobacco Chippers

NCT01237834
View directory record Official record
Conditions
Smoking, Stress
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 55 Years
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting Phase 1 Interventional

Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents

NCT06575738
View directory record Official record
Conditions
Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory, Bariatric Surgery, Anti-obesity Agents
Interventions
Injectable semaglutide or injectable tirzepatide, Standard postoperative care
Drug · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 24 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Physiologic Monitoring of Antidepressant Treatment Response

NCT00759317
View directory record Official record
Conditions
Depression
Interventions
venlafaxine (Effexor)
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2002
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2014 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of Breathwork Intervention With Older Adults After Knee Surgery

NCT07464860
View directory record Official record
Conditions
Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological, Breathing Techniques, Breathing Exercises, Hypothalamic Pituitary Adrenal, Relaxation, Relaxation Therapy, Cortisol, Postoperative Pain, Postoperative Anxiety, Postoperative Depression, Quality of Recovery (QoR-15)
Interventions
A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Animal Assisted Intervention With Dogs for Children With ADHD

NCT05102344
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Behavioral Social Skills Training, Animal Assisted Intervention
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
7 Years to 9 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Phase 3 Interventional Results available

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis

NCT03667690
View directory record Official record
Conditions
Candidemia, Mycoses, Fungal Infection, Invasive Candidiases
Interventions
Rezafungin for Injection, Caspofungin, Fluconazole, intravenous placebo, oral placebo
Drug
Lead sponsor
Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
19
States / cities
Birmingham, Alabama • Sacramento, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sitting Interruption and Whole-body Cardiovascular Health

NCT05316571
View directory record Official record
Conditions
Sedentary Behavior, Sedentary Time
Interventions
One 5-Minute Walking Bout Each Hour, One 15-Minute Standing Bout Each Hour, One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour, Uninterrupted Sitting
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
30 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Active, not recruiting Phase 2 Interventional

Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD Therapeutics

NCT03002389
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Anoro Ellipta, Arnuity Ellipta
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Keswick, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Jul 24, 2026, 2:50 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Perception of Physical Exertion in Healthy Weight and Obese Adolescents

NCT01695785
View directory record Official record
Conditions
Physiological Response to Exercise, Perception of Exercise Difficulty
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
13 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 9, 2015 · Synced Jul 24, 2026, 2:50 AM EDT
Active, not recruiting Not applicable Interventional

The Effects of Virtual Reality Greenspace on Stress Among Adults With Mobility Impairments

NCT06682143
View directory record Official record
Conditions
Mobility Impairments
Interventions
Virtual Reality (VR), Control
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Responses to Varying Environments in Virtual Reality Simulations

NCT04465240
View directory record Official record
Conditions
Residential Characteristics, Emotions, Stress, Psychological, Stress, Physiological
Interventions
Virtual reality
Other
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of the Physiological Response to Sugar on Brain Activity and Behavior

NCT06015490
View directory record Official record
Conditions
Food Preferences, Appetitive Behavior
Interventions
Sucrose drink, Glucose drink, Fructose drink
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 45 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Casinomacropeptide and Satiety

NCT01587911
View directory record Official record
Conditions
Lack of Satiety, Excess Intake of Macronutrients, Appetite Disorders
Interventions
Whey, Whey-CMP, Control, CMP, MPI, CPI
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2017 · Synced Jul 24, 2026, 2:50 AM EDT
Enrolling by invitation Not applicable Interventional

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

NCT07499128
View directory record Official record
Conditions
Cytokine Release Syndrome, Neoplasms, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Multiple Myeloma, Lymphoma Mantle-cell, Immunotherapy, Cell and Tissue-Based Therapy, Cytokines, Monitoring Physiologic, Immune Monitoring, Wearable Electronic Devices, Thermometry, Body Temperature, Antibodies Bispecific, Receptors Chimeric Antigen
Interventions
TempTraq, VitalTraq
Device
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Completed No phase listed Observational

Measurements of Anemia and Physiologic Tissue Response to Blood Transfusions in VLBW Infants Using Quantitative NIRS

NCT00544375
View directory record Official record
Conditions
Infant Development
Interventions
Optical measurement
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Minute to 1 Month
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Physiological Responses to Heat Stress During High-risk Events

NCT06907225
View directory record Official record
Conditions
Thermoregulation
Interventions
None-placebo
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Fort Novosel, Alabama • Fort Jackson, South Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Caffeinated Beverages on Well-being

NCT07357818
View directory record Official record
Conditions
Healthy, Caffeine, Beverage Intake
Interventions
Participants' typical caffeinated beverage, Test caffeinated beverage
Other
Lead sponsor
GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Industry
Eligibility
18 Years to 55 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Functional Neuroanatomy of the Human Physiological Stress Response

NCT03867344
View directory record Official record
Conditions
Hypoglycemia, Physiological Stress
Interventions
Hypoglycemic Hyperinsulinemic Clamp, Normoglycemic Hyperinsulinemic Clamp
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 4, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

One Week Comparison Study of PTH and PTHrP Infusions

NCT01333267
View directory record Official record
Conditions
Osteoporosis, Hypercalcemia of Malignancy, Hyperparathyroidism, Bone Diseases, Endocrine
Interventions
Parathyroid Hormone-related Protein (1-36), parathyroid hormone (1-34), PTH (1-34) and PTHrP (1-36)
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
24 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Race, Natriuretic Peptides and Physiological Perturbations

NCT03070184
View directory record Official record
Conditions
Healthy, Pre Hypertension
Interventions
Exercise capacity VO2 max determination, Standardized meals, Exercise challenge, Metoprolol Succinate ER
Other · Dietary Supplement · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response

NCT06983730
View directory record Official record
Conditions
Heat Strain, Healthy Volunteer Study, Kidney Dysfunction
Interventions
Vitamin B3
Dietary Supplement
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 24, 2026, 2:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

NCT05217589
View directory record Official record
Conditions
Other Gastrointestinal Disorders, Cramp, Abdominal
Interventions
Funny/Amusing Video Clips, Horror/Scary Video Clips, Thrilling/Suspenseful Video Clips
Other
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Jul 24, 2026, 2:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale

NCT06152549
View directory record Official record
Conditions
Stress, Psychological, Stress, Emotional
Interventions
Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge, Standardized Maths and Verbal Questions such as the ones used in SATs, Chronology of Perceived Discrimination Scale (CPDS), International Personality Item Pool (IPIP-NEO)
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jul 24, 2026, 2:50 AM EDT
Completed Not applicable Interventional

Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli

NCT03206437
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Post Traumatic Stress Disorder, Agoraphobia, Simple Phobia
Interventions
Mindfulness-Based Stress Reduction, Waitlist
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Jul 24, 2026, 2:50 AM EDT