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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pigmented Lesions Clear all
Completed Not applicable Interventional

In Vivo Confocal Microscopy for Pigmented Lesion Diagnosis

NCT00785369
View directory record Official record
Conditions
Skin Cancer, Melanoma, Lentigo Maligna
Interventions
Reflectance confocal microscopy
Device
Lead sponsor
Lucid, Inc.
Industry
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
6
States / cities
Loma Linda, California • Plantation, Florida • Hauppauge, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Efficacy and Safety of PiQo4 System for the Treatment of Pigmented Lesions

NCT03565146
View directory record Official record
Conditions
Pigmentation
Interventions
PiQo4 Laser System
Device
Lead sponsor
Focus Medical, LLC
Industry
Eligibility
21 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Jun 10, 2026, 1:36 PM EDT
Completed No phase listed Observational

DermTech's Non-Invasive Pigmented Lesion Assay to Detect and Track Lesions for Suspected Melanoma and to Determine Outcomes for up to 2 Years

NCT04563949
View directory record Official record
Conditions
Melanoma Detection
Interventions
Repeat Testing
Other
Lead sponsor
DermTech
Other
Eligibility
21 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Jun 10, 2026, 1:36 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

NCT05463796
View directory record Official record
Conditions
Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors, Adult Cancer Survivors, IARC Carcinogens, Smoking History, Lung Cancer, Ductal/Lobular Carcinoma, Barrett Esophagus, Pancreatic Precursor Lesions, Colonic Dysplasia/Adenomata, Non-Alcoholic Fatty Liver Disease, Non Alcoholic Steatohepatitis, Cirrhosis, High Grade Prostatic Epithelial Neoplasia, High-grade Bladder Urothelial Dysplasia/Carcinoma in Situ, Adenomatous Hyperplasia, High-risk Oral Precancerous Diseases, Melanocytic Lesion, Adult, Hematologic Malignancy, Lung; Node, Serous Tubal Intraepithelial Carcinoma, Endometrial Intraepithelial Neoplasia, Cervical and Endocervical Carcinoma in Situ, Vulvar Intraepithelial Neoplasia, Nephrogenic Rests, Benign Bone Lesions With Risk of Malignant Degeneration, Giant Cell Tumor, Osteochondroma, Spitz Nevus
Interventions
Samples
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2032
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nonablative Fractional Diode Laser for Treatment of Pigmented Lesions

NCT04202419
View directory record Official record
Conditions
Pigmented Skin Lesion
Interventions
FRAX 1940 nm laser
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Jun 10, 2026, 1:36 PM EDT
Terminated Phase 3 Interventional Results available

A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study

NCT04269395
View directory record Official record
Conditions
Keratosis, Actinic
Interventions
MAL Cream, Vehicle cream
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
52
States / cities
Fort Smith, Arkansas • Encinitas, California • Fountain Valley, California + 43 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jun 10, 2026, 1:36 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

AV-23-001 AVAVA MIRIA Pilot Study

NCT06557434
View directory record Official record
Conditions
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic, Pigmented Lesions, Skin Laxity, Scars
Interventions
MIRIA
Device
Lead sponsor
AVAVA, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Dix Hills, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Broadband Light Treatment for Pigmented Skin Lesions

NCT05750914
View directory record Official record
Conditions
Pigmentation
Interventions
Broadband Light
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Victor, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Jun 10, 2026, 1:36 PM EDT
Completed No phase listed Observational

Sample Collection Study in Patients With Suspected Melanoma Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits

NCT04550000
View directory record Official record
Conditions
Melanoma (Skin), Pigmented Skin, Nevus
Interventions
Not listed
Lead sponsor
DermTech
Other
Eligibility
21 Years and older
Enrollment
652 participants
Timeline
2019 – 2022
U.S. locations
2
States / cities
Chevy Chase, Maryland • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Post Market Study To Collect Efficacy Data For The Treatment Of Wrinkles With A Radiofrequency Device

NCT05096247
View directory record Official record
Conditions
Wrinkle, Benign Pigmented Lesions, Benign Vascular Lesions
Interventions
TempSure, Icon
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Westford, Massachusetts • Portsmouth, New Hampshire • Huntersville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Post Market Study Using The Elite IQ Device

NCT04807205
View directory record Official record
Conditions
Hair Removal, Pseudo Folliculitis Barbae, Benign Vascular Lesion, Pigmented Lesions
Interventions
RF Non-Invasive Treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluation of Pigmented Skin Lesions With MelaFind(R) System

NCT00434057
View directory record Official record
Conditions
Melanoma
Interventions
MelaFind(R)
Device
Lead sponsor
MELA Sciences, Inc.
Industry
Eligibility
Not listed
Enrollment
1,383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Plantation, Florida • Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Jun 10, 2026, 1:36 PM EDT
Completed No phase listed Observational

Spectral Diagnosis of Cutaneous Malignancy

NCT00476905
View directory record Official record
Conditions
Skin Cancer
Interventions
Spectral Diagnosis Probe
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Jun 10, 2026, 1:36 PM EDT
Terminated No phase listed Observational

In Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions

NCT01993654
View directory record Official record
Conditions
Nevus, Racial Melanosis, Primary Acquired Melanosis, Conjunctival Malignant Melanoma
Interventions
HRT III with Non-Contact Cornea Rostock Module
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2016 · Synced Jun 10, 2026, 1:36 PM EDT
Completed No phase listed Observational

Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo

NCT00574392
View directory record Official record
Conditions
Basal Cell Carcinoma, Melanoma, Non-Malignant Skin Disorders, Squamous Cell Carcinoma
Interventions
Multiwavelength and coherence confocal reflectance microscopy (Vivascope 1500m multiwavelength)
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2015 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dermal Cryotherapy for Treatment of Pigmented Lesions

NCT02848742
View directory record Official record
Conditions
Pigmented Skin Lesion
Interventions
Dermal Cooling System
Device
Lead sponsor
R2 Dermatology
Industry
Eligibility
18 Years and older
Enrollment
377 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

fPAM for the in Vivo Depth Measurement of Pigmented Lesions and Melanoma Depth

NCT02613325
View directory record Official record
Conditions
Pigmented Skin Lesion, Melanoma
Interventions
Functional photoacoustic microscopy, Standard of care surgical excision, Single cell photoacoustic microscopy
Device · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lutronic LaseMD for Treatment of Benign Pigmented Lesions

NCT03409952
View directory record Official record
Conditions
Benign Pigmented Lesions
Interventions
LaseMD and DUAL 1927nm Laser, LaseMD
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Hunt Valley, Maryland • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perceptual Expertise Training for Triage of Moles

NCT03246633
View directory record Official record
Conditions
Lesion; Pigment, Diagnostic Self Evaluation
Interventions
Perceptual Training
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Dermal Cooling System for the Enhanced Treatment of Benign Pigmented Lesions and Common Skin Conditions

NCT04493021
View directory record Official record
Conditions
Pigmentation
Interventions
Dermal Cooling System
Device
Lead sponsor
R2 Dermatology
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Evaluation of the 755nm Alexandrite for the Treatment of Epidermal and Dermal Pigmented Lesions

NCT01754233
View directory record Official record
Conditions
Dermal and Epidermal Pigmented Lesions
Interventions
755nm Alexandrite Laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 25, 2020 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

PicoWay™ 730 Resolve Fusion for Benign Pigmented Lesions and Wrinkles

NCT03774849
View directory record Official record
Conditions
Benign Pigmented Lesions, Facial Wrinkles
Interventions
PicoWay™ 532nm fractional handpiece, PicoWay™ 730nm wavelength, PicoWay™ 1064nm fractional handpiece
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wayland, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Jun 10, 2026, 1:36 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Post-Approval Study of MelaFind

NCT01700114
View directory record Official record
Conditions
Melanoma
Interventions
MelaFind
Device
Lead sponsor
MELA Sciences, Inc.
Industry
Eligibility
Not listed
Enrollment
487 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
6
States / cities
Englewood, Colorado • Tallahassee, Florida • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2016 · Synced Jun 10, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Broadband Light Treatment Protocol for Pigmented Skin Lesions - A Comparative Study

NCT05662592
View directory record Official record
Conditions
Pigmentation
Interventions
Broadband Light
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Jun 10, 2026, 1:36 PM EDT