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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pigmented Skin Lesion Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Lutronic PicoPlus Exploratory Clinical Trial

NCT03415685
View directory record Official record
Conditions
Tattoo; Pigmentation, Melasma, Benign Pigmented Lesion
Interventions
PicoPlus laser system
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
18 Years to 60 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Newport Beach, California • Elmhurst, New York • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Picosecond Laser for Ttreatment of Benign Pigmented Lesions

NCT02146820
View directory record Official record
Conditions
Benign Pigmented Lesions
Interventions
GentleMax system
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2015 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional

Evaluation of the 755nm Alexandrite Laser for Skin Toning and Epidermal Pigmented Lesions in Asian Skin Types

NCT01754246
View directory record Official record
Conditions
Epidermal Pigmented Lesions, Skin Toning
Interventions
755nm Alexandrite Laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Dermal Cooling System for the Enhanced Treatment of Benign Pigmented Lesions and Common Skin Conditions

NCT04493021
View directory record Official record
Conditions
Pigmentation
Interventions
Dermal Cooling System
Device
Lead sponsor
R2 Dermatology
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Skin Imaging With Technologies in Development

NCT00764920
View directory record Official record
Conditions
Pigmented Skin Lesion of Uncertain Nature
Interventions
non-invasive imaging modalities for assessment of skin
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
7 Years and older
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nonablative Fractional Diode Laser for Treatment of Skin Resurfacing and Pigmented Lesions

NCT04203745
View directory record Official record
Conditions
Skin Texture, Pigmented Lesions
Interventions
Nonablative Fractional Diode Laser
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

AV-23-001 AVAVA MIRIA Pilot Study

NCT06557434
View directory record Official record
Conditions
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic, Pigmented Lesions, Skin Laxity, Scars
Interventions
MIRIA
Device
Lead sponsor
AVAVA, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Dix Hills, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Evaluation of Smart vs HERO Broadband Light Treatment for Pigmented Skin Lesions

NCT04936919
View directory record Official record
Conditions
Pigmented Lesions
Interventions
BroadBand Light
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Gatos, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Recruiting No phase listed Observational

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

NCT07675967
View directory record Official record
Conditions
Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus, Solid Cancers, Breast Cancer, Gastric (Stomach) Cancer, Colorectal (Colon or Rectal) Cancer, Sarcoma, Ovarian Adenocarcinoma, Uterine Adenocarcinoma, Endometrial Adenocarcinoma, Esophageal Adenocarcinoma, Head and Neck Cancer, Therapy-Related Acute Myeloid Leukemia, Therapy-Related MDS, Clonal Hematopoiesis of Indeterminate Potential (CHIP), Clonal Cytopenia of Undetermined Significance
Interventions
Samples
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 7, 2026, 4:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Pilot Study to Evaluate Optical Spectroscopy of Pigmented Skin Lesions

NCT00633516
View directory record Official record
Conditions
Skin Cancer
Interventions
Optical Spectroscopy
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
2
States / cities
Irvine, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development and Validation of a Quality of Life Instrument for Actinic Keratosis

NCT01444989
View directory record Official record
Conditions
Actinic Keratosis
Interventions
AKRQ questionnaire, Skindex-16, DLQI, Skin Health Calculator
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 7, 2026, 4:37 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Post-Approval Study of MelaFind

NCT01700114
View directory record Official record
Conditions
Melanoma
Interventions
MelaFind
Device
Lead sponsor
MELA Sciences, Inc.
Industry
Eligibility
Not listed
Enrollment
487 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
6
States / cities
Englewood, Colorado • Tallahassee, Florida • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2016 · Synced Sep 7, 2026, 4:37 AM EDT
Completed No phase listed Observational

Spectral Diagnosis of Cutaneous Malignancy

NCT00476905
View directory record Official record
Conditions
Skin Cancer
Interventions
Spectral Diagnosis Probe
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Evaluation of a Novel Multi-Wavelength Laser for Benign Pigmented Lesion Removal

NCT02635880
View directory record Official record
Conditions
Pigmented Skin Lesion of Suspected Benign Nature
Interventions
Investigational Enlighten Device
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of Broad Band Light In Motion Treatment

NCT03970317
View directory record Official record
Conditions
Pigmentation
Interventions
Broad Band Light
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Gatos, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 7, 2026, 4:37 AM EDT
Terminated Phase 3 Interventional Results available

A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study

NCT04269395
View directory record Official record
Conditions
Keratosis, Actinic
Interventions
MAL Cream, Vehicle cream
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
52
States / cities
Fort Smith, Arkansas • Encinitas, California • Fountain Valley, California + 43 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perceptual Expertise Training for Triage of Moles

NCT03246633
View directory record Official record
Conditions
Lesion; Pigment, Diagnostic Self Evaluation
Interventions
Perceptual Training
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Imaging Human Skin With High-Speed Spectrally Encoded Confocal Microscopy

NCT04566302
View directory record Official record
Conditions
Pigmented Lesions, Pigmented Skin Lesion, Pigmented Moles, Skin Lesion
Interventions
SECM Skin Imaging
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

fPAM for the in Vivo Depth Measurement of Pigmented Lesions and Melanoma Depth

NCT02613325
View directory record Official record
Conditions
Pigmented Skin Lesion, Melanoma
Interventions
Functional photoacoustic microscopy, Standard of care surgical excision, Single cell photoacoustic microscopy
Device · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro Plus

NCT04993066
View directory record Official record
Conditions
Pseudofolliculitis Barbae, Unwanted Hair, Pigmented Lesions, Vascular Lesion, Onychomycosis, Wrinkle, Acne
Interventions
GentleMax Pro Plus
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nonablative Fractional Diode Laser for Treatment of Pigmented Lesions

NCT04202419
View directory record Official record
Conditions
Pigmented Skin Lesion
Interventions
FRAX 1940 nm laser
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Broadband Light Treatment Protocol for Pigmented Skin Lesions - A Comparative Study

NCT05662592
View directory record Official record
Conditions
Pigmentation
Interventions
Broadband Light
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 7, 2026, 4:37 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluation of Pigmented Skin Lesions With MelaFind(R) System

NCT00434057
View directory record Official record
Conditions
Melanoma
Interventions
MelaFind(R)
Device
Lead sponsor
MELA Sciences, Inc.
Industry
Eligibility
Not listed
Enrollment
1,383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Plantation, Florida • Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Sep 7, 2026, 4:37 AM EDT
Completed No phase listed Observational

Sample Collection Study in Patients With Suspected Melanoma Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits

NCT04550000
View directory record Official record
Conditions
Melanoma (Skin), Pigmented Skin, Nevus
Interventions
Not listed
Lead sponsor
DermTech
Other
Eligibility
21 Years and older
Enrollment
652 participants
Timeline
2019 – 2022
U.S. locations
2
States / cities
Chevy Chase, Maryland • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Sep 7, 2026, 4:37 AM EDT