- Conditions
- Plague, Pneumonic, Plague, Vaccine-Preventable Diseases
- Interventions
- rF1V-1018, rF1V vaccine
- Biological
- Lead sponsor
- Dynavax Technologies Corporation
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 6
- States / cities
- Huntsville, Alabama • San Diego, California • Melbourne, Florida + 3 more
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- Conditions
- Plague, Plague, Bubonic, Plague, Pneumonic, Yersinia Pestis Plague, Yersinia Pestis; Bubo, Yersinia Pestis; Pneumonia, Yersinia Sepsis, Yersinia Pestis Infection, Bubo; Yersinia Pestis, Bubonic; Plague, Skin, Pneumonic Plague
- Interventions
- Lateral Flow Assay for Pathogens of the Plague
- Diagnostic Test
- Lead sponsor
- Brimrose Technology Corporation
- Industry
- Eligibility
- 5 Years to 75 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Prevention of Pneumonic Plague Resulting From Aerosol Exposure to Yersenia Pestis
- Interventions
- rF1V-1018
- Biological
- Lead sponsor
- Dynavax Technologies Corporation
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 148 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 3
- States / cities
- Miami, Florida • El Dorado, Kansas • Las Vegas, Nevada
- Conditions
- Pre-exposure Prophylaxis Against Pneumonic Plague in Healthy Adults
- Interventions
- Monoclonal antibody JST-010, Placebo
- Biological · Drug
- Lead sponsor
- Just-Evotec Biologics
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 104 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Pneumonic Plague, Preventive Therapy
- Interventions
- rF1V vaccine
- Biological
- Lead sponsor
- DynPort Vaccine Company LLC, A GDIT Company
- Industry
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2006
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky