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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pollution; Exposure Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Health Effects of Repeated Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Volunteers

NCT05323240
View directory record Official record
Conditions
Air Pollution
Interventions
PM exposure, Filtered air exposure
Other
Lead sponsor
U.S. EPA Human Studies Facility
Federal
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 26, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

NCT05874479
View directory record Official record
Conditions
Blood Pressure
Interventions
Active PAC, Sham PAC
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Not listed Phase 2 Interventional

Healthy Outcomes of Pregnancy Education

NCT00381823
View directory record Official record
Conditions
Environmental Tobacco Smoke Exposure, Depression, Partner Abuse, Tobacco Smoking
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2006 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers

NCT02469428
View directory record Official record
Conditions
Exposure to Environmental Pollution, Non-occupational
Interventions
Clean air, Ozone
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 26, 2026, 5:50 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Innate Immunity in Ozone-induced Airway Inflammation in COPD

NCT04669743
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Airway Disease, COPD Exacerbation, Pollution; Exposure, Pollution Related Respiratory Disorder
Interventions
Ozone exposure
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
45 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
3
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Air Pollution and Physical Activity Study

NCT06386055
View directory record Official record
Conditions
Physical Inactivity, Pollution; Exposure
Interventions
Active exercise
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
35 Years to 55 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of Diesel Exhaust and Ozone Exposure

NCT01492517
View directory record Official record
Conditions
Exposure to Pollution, Inhalation of Ozone
Interventions
Ozone exposure, Diesel exhaust, Ozone18, Clean Air
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Solar Lighting to Reduce Indoor Air Pollution in Rural Uganda

NCT03351504
View directory record Official record
Conditions
Pollution; Exposure, Hypertension, Pollution Related Respiratory Disorder
Interventions
Solar lighting system
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional

Cleaner Air for Lower Cardiometabolic Risk

NCT05994937
View directory record Official record
Conditions
PreDiabetes
Interventions
PAC with HEPA filter intact, PAC with HEPA filter removed
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Human Biological Responses to Low Level Ozone

NCT02857283
View directory record Official record
Conditions
Environmental Exposure, Nasal Inflammation
Interventions
Ozone, Filtered Air, Health and Exposure Tracker (HET)
Other · Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Sequential Exposure to Nitrogen Dioxide and Ozone in Healthy Adult Human Volunteers.

NCT02133586
View directory record Official record
Conditions
Respiratory Depression
Interventions
Ozone, Nitrogen dioxide
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years to 40 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional

Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study

NCT06384625
View directory record Official record
Conditions
Coronary Heart Disease, Cardiovascular Diseases, Environmental Exposure
Interventions
AIRWISE
Other
Lead sponsor
University of Montana
Other
Eligibility
55 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 26, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Melanin and Dermal Uptake of Thirdhand Cigarette Smoke

NCT06020248
View directory record Official record
Conditions
Healthy
Interventions
Wear clothing that has been exposed to cigarette smoke for 3 hours.
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rural Appalachia Pilot Water Treatment Trial

NCT06120985
View directory record Official record
Conditions
Water-Related Diseases, Enteric Pathogens, Exposure to Chemical Pollution
Interventions
Countertop pitcher water filter
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
6 Months and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Johnson City, Tennessee • Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Completed No phase listed Observational Results available

Change in Knowledge After Receiving Personal Air Pollution Results

NCT05160948
View directory record Official record
Conditions
Environmental Exposure
Interventions
Informational Report
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
15 Years to 99 Years
Enrollment
105 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Diesel Exhaust Particulate Exposures on Endothelial Function in Humans

NCT00434005
View directory record Official record
Conditions
Healthy
Interventions
N-acetylcysteine, ascorbate, Placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 49 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Sep 26, 2026, 5:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Transportation Choices on Commuter Health

NCT05758714
View directory record Official record
Conditions
Pollution; Exposure
Interventions
Not listed
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 99 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Milwaukee Day Cares Indoor Air Quality Assessment and Educational Response Study

NCT03675009
View directory record Official record
Conditions
Pollution; Exposure
Interventions
Educational Programming
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Air Pollution: Strategies for Personalized Intervention to Reduce Exposure

NCT03744871
View directory record Official record
Conditions
Air Pollution
Interventions
N95 Respirator
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 3, 2023 · Synced Sep 26, 2026, 5:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Omega-3 Fatty Acids in Ambient Air Pollution Exposure in Healthy Adults

NCT02921048
View directory record Official record
Conditions
Health Effects of Ambient Air Pollution
Interventions
omega-3 fatty acids
Dietary Supplement
Lead sponsor
U.S. EPA Human Studies Facility
Federal
Eligibility
25 Years to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Effect of Daily CARDIO® Capsules Supplementation on Improved Sleep in Healthy, Urban-Dwelling Adults

NCT06768970
View directory record Official record
Conditions
Sleep, Pollution; Exposure, Cough
Interventions
CARDIO® salmon oil
Dietary Supplement
Lead sponsor
Hofseth Biocare ASA
Industry
Eligibility
18 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 26, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Juice Types on the Responses to Air Pollution

NCT02027415
View directory record Official record
Conditions
Air Pollution
Interventions
Beet juice, Orange juice
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 26, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Macrophage Activation in Lung Injury Following Ozone Exposure

NCT05794087
View directory record Official record
Conditions
Air Pollution
Interventions
Clean Air, Ozone
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 26, 2026, 5:50 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke

NCT04013256
View directory record Official record
Conditions
Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
Interventions
Cigarette Smoke, Clean Air and Clean Clothing/Sham exposure
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2023 · Synced Sep 26, 2026, 5:50 PM EDT