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ClinicalTrials.gov public records Last synced Oct 8, 2026, 5:34 AM EDT

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Showing 241–264 of 273 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Positive-Pressure Respiration Clear all
Not listed Not applicable Interventional

The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study

NCT01121445
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
NeilMed nose and sinus irrigation
Device
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated May 12, 2010 · Synced Oct 8, 2026, 5:34 AM EDT
Terminated Not applicable Interventional Results available

Assessment Of The Effects Of Short and Long Term Use Of CPAP

NCT00592631
View directory record Official record
Conditions
Asthma
Interventions
CPAP-Continuous Positive Airway Pressure, SHAM
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea

NCT00089752
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Hypertension
Interventions
Continuous Positive Airway Pressure (CPAP) Treatment, Sham CPAP device - CPAP device with pressure delivered <1 cm H20
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
4
States / cities
Denver, Colorado • Atlanta, Georgia • Long Island City, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 8, 2026, 5:34 AM EDT
Not listed Not applicable Interventional

Peer-Driven Intervention for Sleep Apnea

NCT02056002
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Usual Care, Peer-Buddy System
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 85 Years
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Oct 8, 2026, 5:34 AM EDT
Terminated Not applicable Interventional Results available

Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants

NCT03558737
View directory record Official record
Conditions
Infant,Premature, Respiratory Failure, Respiratory Insufficiency, Respiratory Distress Syndrome in Premature Infant
Interventions
Nasal high-frequency jet ventilation (nHFJV), Nasal intermittent positive pressure ventilation (NIPPV)
Other
Lead sponsor
University of Utah
Other
Eligibility
Up to 72 Hours
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Phase 2 Interventional Results available

Dimethyl Fumarate for Obstructive Sleep Apnea

NCT02438137
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA, Sleep Apnea
Interventions
Dimethyl fumarate, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 8, 2026, 5:34 AM EDT
Not yet recruiting Not applicable Interventional

KPAP Adherence Crossover Study

NCT06413134
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
KPAP, APAP
Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Atrial Fibrillation Recurrence in Sleep Apnea

NCT00263757
View directory record Official record
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Adaptive Servo-Ventilation, Usual Care
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 8, 2026, 5:34 AM EDT
Terminated Not applicable Interventional Results available

Comparison Study of the ICON™ Auto Series With and Without SensAwake™ and ThermoSmart™ and Conventional Continuous Positive Airway Pressure in Obstructive Sleep Apnea Patients

NCT01517763
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Conventional CPAP Therapy, Fixed pressure ICON™ without ThermoSmart™, Auto ICON™ with SensAwake™ and ThermoSmart™
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Oct 8, 2026, 5:34 AM EDT
Terminated Not applicable Interventional Results available

The Efficacy of a New Mathematical Formula to Predict Continuous Positive Air Pressure With an Oronasal Mask Interface.

NCT02816255
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Full Face Mask with same CPAP Pressure, Full Face Mask with new Pressure
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

NCT00116558
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Early NIPPV, Standard NIPPV
Device
Lead sponsor
Edward Kasaraskis
Other
Eligibility
18 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
12
States / cities
Denver, Colorado • Miami, Florida • Lexington, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder

NCT01569022
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, MAD
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Oct 8, 2026, 5:34 AM EDT
Recruiting Not applicable Interventional

HFNC vs NIPPV Following Extubation

NCT05869825
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation
Procedure
Lead sponsor
Emory University
Other
Eligibility
Up to 1 Year
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)

NCT01381068
View directory record Official record
Conditions
Delivery Room Resuscitation
Interventions
End tidal CO2 monitor
Device
Lead sponsor
Neil Finer
Other
Eligibility
Up to 15 Minutes
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Self-Management of Continuous Positive Airway Pressure Settings

NCT03536572
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Sleep Apnea Self-Management Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 8, 2026, 5:34 AM EDT
Withdrawn Not applicable Interventional

Effects of PAP Treatment of OSA in Patients With Heart Failure

NCT01136122
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP Treatment
Device
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neo RQI: The Effect of Neonatal Resuscitation Quality Improvement Cart Booster Training Skills Retention

NCT05147922
View directory record Official record
Conditions
Ventilatory Failure
Interventions
Booster Training with the Neonatal Resuscitation Quality Improvement Cart
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 8, 2026, 5:34 AM EDT
Terminated Phase 1Phase 2 Interventional

PEEP and V/Q Mismatch in Premature Infants

NCT03109613
View directory record Official record
Conditions
Respiratory Insufficiency Syndrome of Newborn, Infant, Premature, Diseases
Interventions
Positive end-expiratory pressure (PEEP)
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Days to 28 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Newark, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Phase 3 Interventional Results available

Apnea Positive Pressure Long-Term Efficacy Study

NCT00051363
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Sleep
Interventions
Active CPAP, Sham CPAP
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
5
States / cities
Tucson, Arizona • Palo Alto, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 8, 2026, 5:34 AM EDT
Withdrawn Not applicable Interventional

Effects of PAP on Afib Recurrence Risk After Catheter Ablation in OSA Patients

NCT03242720
View directory record Official record
Conditions
Obstructive Sleep Apnea, Atrial Fibrillation
Interventions
Cardiac Ablation for Atrial Fibrillation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Not applicable Interventional Results available

Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment

NCT00252629
View directory record Official record
Conditions
Apnea, Sleep, Chronic Fatigue Syndrome
Interventions
Nasal CPAP treatment during sleep
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
32 Years to 52 Years · Male only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2014 · Synced Oct 8, 2026, 5:34 AM EDT
Completed Phase 2 Interventional Results available

Effects of Treating Obstructive Sleep Apnea in Epilepsy

NCT00047463
View directory record Official record
Conditions
Epilepsy, Sleep Apnea, Obstructive Sleep Apnea
Interventions
continuous positive airway pressure (CPAP), Placebo-CPAP
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
4
States / cities
Ann Arbor, Michigan • Chapel Hill, North Carolina • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2016 · Synced Oct 8, 2026, 5:34 AM EDT
Withdrawn Phase 4 Interventional

Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients

NCT04205136
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Oct 8, 2026, 5:34 AM EDT
Completed No phase listed Observational

Ventilation and Esophageal Pressure Changes

NCT05859672
View directory record Official record
Conditions
Mechanical Ventilation
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 8, 2026, 5:34 AM EDT