- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Interventions
- IPACK, PLACEBO
- Drug
- Lead sponsor
- Loyola University
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Maywood, Illinois
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Showing 1–24
of 75
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- ACL Injury
- Interventions
- Bupivacaine
- Drug
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Plainview, New York
- Conditions
- Anterior Cruciate Ligament Tear, Pain, Postoperative, Opioid Use
- Interventions
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Drug
- Lead sponsor
- Carilion Clinic
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- Plyometric Exercise
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 15 Years to 30 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- ACL Repair
- Interventions
- Cryoneurolysis
- Procedure
- Lead sponsor
- Virtua Health, Inc.
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- Burlington, New Jersey • Cherry Hill, New Jersey
- Conditions
- ACL Tear
- Interventions
- Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
- Device · Other
- Lead sponsor
- Candice Dunkin, MS, LAT, ATC
- Other
- Eligibility
- 16 Years to 22 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- ACL Injury
- Interventions
- Autologous bone grafting, Absence of autologous bone grafting
- Procedure
- Lead sponsor
- Hartford Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 3
- States / cities
- Hartford, Connecticut
- Conditions
- Injury of Anterior Cruciate Ligament
- Interventions
- bupivacaine, continuous perineural infusion catheter
- Drug · Device
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Pain, Postoperative, Opioid Use
- Interventions
- Perioperative Pain Management Education and Counseling
- Behavioral
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 121 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
- Interventions
- Montelukast, Placebo
- Drug
- Lead sponsor
- Austin V Stone
- Other
- Eligibility
- 25 Years to 50 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Anterior Cruciate Ligament Injury, ACL Injury, ACL - Anterior Cruciate Ligament Rupture
- Interventions
- Femoral Nerve Block, Adductor Nerve Block, No Block
- Procedure · Other
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Arthroscopic Surgical Procedures, Anterior Cruciate Ligament Reconstruction
- Interventions
- Activated Incrediwear Products, Sham Incrediwear Products
- Other
- Lead sponsor
- Oklahoma Joint Reconstruction Institute
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- ACL Reconstruction
- Interventions
- Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen
- Drug · Combination Product
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 14 Years to 65 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- ACL, Anterior Cruciate Ligament, ACL Injury
- Interventions
- Placebo Split-Belt Training, Split-Belt Training
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL Injury, Quadriceps Muscle Atrophy
- Interventions
- Blood flow restriction therapy - with Delfi Personalized Tourniquet System, Sham blood flow restriction therapy - with Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Steadman Philippon Research Institute
- Other
- Eligibility
- 14 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Vail, Colorado
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, ACL Injury, Healthy
- Interventions
- Anterior cruciate ligament reconstruction
- Procedure
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- IPACK block
- Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Operant Conditioning, Control
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL, Opioid Use, Cryotherapy Effect, Vibration; Exposure, Pain, Postoperative
- Interventions
- VibraCool mechanical stimulation and neuromodulatory therapeutic device, Cryocompression (Game Ready, Bregs) device, Standard ice packs
- Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- Not listed
- Enrollment
- 130 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope
- Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 14 Years to 65 Years
- Enrollment
- 270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2005
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee, ACL
- Interventions
- Standard Physical Therapy, Ermi Knee Extensionater
- Behavioral · Device
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 14 Years to 65 Years
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Functional Resistance Training with Brace, Control, Functional Resistance Training with Elastic Band
- Other
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 40 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL Injury
- Interventions
- Blood Flow Restriction (BFR) therapy, Standard REHAB
- Other
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 15 Years to 45 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Pain and Anterior Cruciate Ligament Reconstruction
- Interventions
- Dry needling and STM
- Other
- Lead sponsor
- Keller Army Community Hospital
- Federal
- Eligibility
- 18 Years to 40 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- West Point, New York