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Showing 1–24 of 95 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post Cesarean Pain Clear all
Terminated Phase 4 Interventional Results available

Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section

NCT02353754
View directory record Official record
Conditions
Pain
Interventions
Intrathecal morphine injection, EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
5
States / cities
Port Saint Lucie, Florida • Minneapolis, Minnesota • New Brunswick, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Sep 23, 2026, 1:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean

NCT04271072
View directory record Official record
Conditions
Perinatal Depression, Chronic Pain
Interventions
No intervention
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 4 Interventional Results available

Intrathecal Morphine for Cesarean Delivery

NCT05069012
View directory record Official record
Conditions
Postoperative Pain
Interventions
Morphine Sulfate
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 23, 2026, 1:43 AM EDT
Terminated Phase 4 Interventional Results available

Two Dose Epidural Morphine for Post-cesarean Analgesia

NCT01844206
View directory record Official record
Conditions
Pain, Morphine Adverse Reaction
Interventions
Epidural Morphine, Epidural Saline
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2015 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NSS-Bridge Device for Post-Cesarean Delivery Pain

NCT03830307
View directory record Official record
Conditions
Acute Pain, Cesarean Delivery
Interventions
NSS-2-Bridge
Device
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Sep 23, 2026, 1:43 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section

NCT01362998
View directory record Official record
Conditions
Pain
Interventions
Preservative free morphine, Fentanyl
Drug
Lead sponsor
Goodman, Evan, M.D.
Individual
Eligibility
18 Years to 50 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery

NCT03959969
View directory record Official record
Conditions
Opioid Use, Unspecified
Interventions
Educational video, Standard of care, Ibuprofen, Oxycodone
Other · Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Not applicable Interventional Results available

High Pain Intervention in Cesarean Sections

NCT01298778
View directory record Official record
Conditions
Other Chronic Postoperative Pain
Interventions
Duramorph 150, Acetaminophen, Duramorph 300
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 23, 2026, 1:43 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

NCT04368364
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Hydromorphone and C-section

NCT01598545
View directory record Official record
Conditions
Postoperative Pain
Interventions
Hydromorphone
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Sep 23, 2026, 1:43 AM EDT
Not listed Phase 3 Interventional

The Use of Abdominal Binders in Patients Undergoing Cesarean Sections

NCT02129894
View directory record Official record
Conditions
Cesarean Section Post Operative Management
Interventions
abdominal Binder
Device
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 1, 2014 · Synced Sep 23, 2026, 1:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia

NCT00418015
View directory record Official record
Conditions
Labor Pain, Post-cesarean Delivery
Interventions
Blood Draw
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
293 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 23, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional

Post-operative Cesarean Trial of Pain Control

NCT05131178
View directory record Official record
Conditions
Post-operative Pain, Cesarean Section
Interventions
ON-Q Pump® with continuous infusion of bupivacaine, ON-Q Pump® with continuous infusion of saline
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Increased Ketorolac Administration After Cesarean Section and Its Effect on Opioid Use: a Randomized Control Trial

NCT03678675
View directory record Official record
Conditions
Post-operative Pain, Post-partum Pain, Cesarean Section Complications
Interventions
Ketorolac
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2022 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)

NCT02105558
View directory record Official record
Conditions
Labor Pain, Complications; Cesarean Section, Pregnancy
Interventions
Epidural anesthesia, Combined spinal and epidural anesthesia
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Sep 23, 2026, 1:43 AM EDT
Withdrawn Phase 4 Interventional

Liposomal Bupivacaine After Cesarean Delivery

NCT03907813
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use
Interventions
Exparel, Saline infiltration
Drug · Other
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain

NCT02959996
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal bupivacaine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post-operative Patient Positioning Device for Improvement of Post-Operative Pain

NCT04797637
View directory record Official record
Conditions
Pain, Postoperative
Interventions
ABBy® Adjustable Panniculus Retractor for Wound Care
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Not applicable Interventional Results available

Prospective Study on Cesarean Wound Outcomes

NCT01697748
View directory record Official record
Conditions
Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
Interventions
Silver-impregnated dressing, Telfa pad dressing
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Sep 23, 2026, 1:43 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Wound Infiltration as Part of an Opioid Free Pain Management Pathway Following Cesarean Delivery

NCT03545516
View directory record Official record
Conditions
Pain, Postoperative, Anesthesia, Local, Opioid Use
Interventions
Bupivacaine, Dexmedetomidine, Placebo
Drug
Lead sponsor
Richmond University Medical Center
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Sep 23, 2026, 1:43 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management

NCT05360433
View directory record Official record
Conditions
Post Operative Pain
Interventions
Oxycodone oral capsule
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
19 Years to 40 Years · Female only
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Intrathecal Hydromorphone for Cesarean Section

NCT02067520
View directory record Official record
Conditions
Pain
Interventions
intrathecal hydromorphone (IT hydromorphone)
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Sep 23, 2026, 1:43 AM EDT
Completed Phase 4 Interventional Results available

Effect of Mu-opioid Receptor Genetics on 3 Doses of Spinal Morphine for Postoperative Analgesia After Cesarean Section

NCT01465191
View directory record Official record
Conditions
Postoperative Pain
Interventions
Morphine
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Washington D.C., District of Columbia • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Sep 23, 2026, 1:43 AM EDT
Not listed Not applicable Interventional

TAP Catheters Versus Intrathecal Morphine for Cesarean Section

NCT01593280
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Cesarean Section, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP catheter, intrathecal morphine
Device · Drug
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2012 · Synced Sep 23, 2026, 1:43 AM EDT