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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post Intensive Care Syndrome Clear all
Completed Not applicable Interventional

Early Discharge and Outpatient Care After Chemotherapy in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

NCT00844441
View directory record Official record
Conditions
Leukemia, Myelodysplastic Syndromes
Interventions
medical chart review, questionnaire administration, quality-of-life assessment
Other · Procedure
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 18, 2011 · Synced Jun 27, 2026, 12:11 PM EDT
Active, not recruiting No phase listed Observational

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

NCT04967365
View directory record Official record
Conditions
Critical Illness, Post Intensive Care Unit Syndrome
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
1 Month to 16 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
30
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 27, 2026, 12:11 PM EDT
Recruiting Not applicable Interventional

Telehealth-enhanced Patient-oriented Recovery Trajectory After Intensive Care

NCT06014931
View directory record Official record
Conditions
Post-intensive Care Syndrome
Interventions
Telemedicine ICU Recovery Clinic Visit
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
45 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional Results available

CoV-PICS: A Virtual Post-ICU Clinic

NCT04490278
View directory record Official record
Conditions
Post ICU Syndrome
Interventions
Medical Record Review - Inpatient Treatment, Online Questionnaires
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Jun 27, 2026, 12:11 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stress Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU

NCT04476914
View directory record Official record
Conditions
Respiratory Failure, SARS-CoV 2, Corona Virus Infection, Post Intensive Care Unit Syndrome, Family Members, Post Traumatic Stress Disorder, Anxiety, Depression
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
9
States / cities
Aurora, Colorado • New Orleans, Louisiana • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Jun 27, 2026, 12:11 PM EDT
Completed No phase listed Observational

Muscle Dysfunction in Critical Illness

NCT03717831
View directory record Official record
Conditions
Critical Illness, Intensive Care (ICU) Myopathy, PICS, Muscle Weakness
Interventions
Observational study of standard of care
Other
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
66 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional

Reducing Isolation and Feeling of Loneliness During Critical Illness

NCT05537311
View directory record Official record
Conditions
Critical Illness, Social Isolation, Anxiety, Depression, Post Intensive Care Unit Syndrome
Interventions
Social Engagement
Behavioral
Lead sponsor
Kirby Mayer
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional Results available

Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors

NCT03053245
View directory record Official record
Conditions
Acute Respiratory Failure, Post-Intensive Care Syndrome
Interventions
Mobile Critical Care Program, Attention Control
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
3
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 23, 2024 · Synced Jun 27, 2026, 12:11 PM EDT
Recruiting Not applicable Interventional

Improving Outcomes in PICS With Home-Based Program of Rehabilitation and Health Coaching

NCT06184308
View directory record Official record
Conditions
Post-Intensive Care Syndrome
Interventions
Home-based Physical Rehabilitation, Health Coaching
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jun 27, 2026, 12:11 PM EDT
Recruiting Not applicable Interventional

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

NCT07390786
View directory record Official record
Conditions
Critical Illness Recovery, Behavioral Health Concerns, Anxiety, Depression - Major Depressive Disorder, PTSD, Critical Care, Intensive Care, PICS-F
Interventions
Behavioral Treatment
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jun 27, 2026, 12:11 PM EDT
Not listed Not applicable Interventional

Peer Support for Post Intensive Care Syndrome Self-Management

NCT03788096
View directory record Official record
Conditions
Critical Illness, Sepsis, Shock, Septic, Shock, Respiratory Failure, Respiratory Distress Syndrome, Adult, Shock, Hypovolemic, Chronic Disease
Interventions
Peer Support with Motivational Interviewing, Usual Care Group
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Jun 27, 2026, 12:11 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

NCT05357170
View directory record Official record
Conditions
Sepsis, Trauma Injury
Interventions
Human feces collection
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 110 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional

Positive Suggestions Via MP3 Messages

NCT04437095
View directory record Official record
Conditions
Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression, PTSD
Interventions
Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jun 27, 2026, 12:11 PM EDT
Recruiting Not applicable Interventional

Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)

NCT07496255
View directory record Official record
Conditions
Intensive Care Unit Delirium, Intensive Care Acquired Cognitive Impairment, Post Intensive Care Unit Syndrome, Virtual Reality Cognitive Training
Interventions
VR-based cognitive training program, VR-based attention control
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jun 27, 2026, 12:11 PM EDT
Recruiting Not applicable Interventional

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

NCT04989790
View directory record Official record
Conditions
Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 18 Years
Enrollment
1,440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
11
States / cities
Madera, California • Orlando, Florida • Louisville, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jun 27, 2026, 12:11 PM EDT
Completed No phase listed Observational

An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States

NCT06272942
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome (ARDS), Post Intensive Care Syndrome (PICS)
Interventions
An ICU admission and a temporally related ARDS diagnosis
Other
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
640,058 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Whippany, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jun 27, 2026, 12:11 PM EDT
Suspended Not applicable Interventional

Post-Intensive Care Transitional Care, Rehabilitation, and Family-Support

NCT06501365
View directory record Official record
Conditions
Intensive Care Unit Syndrome, Disabilities Multiple, Critical Illness, Caregiver Burden
Interventions
Post Intensive Care Transitions Rehabilitation and Family Support (PIC-TRFS), Enhanced Usual Care Control
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional

Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19

NCT04412330
View directory record Official record
Conditions
Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
Interventions
ICU Recovery + Physical Therapy
Other
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Jun 27, 2026, 12:11 PM EDT
Completed No phase listed Observational

Collaborative Assessment of ICU Recovery Needs

NCT03513289
View directory record Official record
Conditions
Post-Intensive Care Syndrome
Interventions
Patient, Carer, and Clinician Interviews
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Jun 27, 2026, 12:11 PM EDT
Terminated Not applicable Interventional

Telemonitoring Device in Managing Outpatient Care of Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia After Intensive Chemotherapy

NCT02226497
View directory record Official record
Conditions
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Interventions
Health Telemonitoring, Quality-of-Life Assessment, Questionnaire Administration, Supportive Care
Device · Other · Procedure
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional Results available

Psychological Symptoms and Families of COVID-19 Patients

NCT04501445
View directory record Official record
Conditions
Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
Interventions
Written Summary of Rounds
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Jun 27, 2026, 12:11 PM EDT
Completed No phase listed Observational

Observational Study of Expected ARF Recovery

NCT03797313
View directory record Official record
Conditions
Acute Respiratory Failure, Post Intensive Care Syndrome
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Baltimore, Maryland • Boston, Massachusetts • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Jun 27, 2026, 12:11 PM EDT
Completed Not applicable Interventional

Intensive Care Unit (ICU) Diary Project

NCT04305353
View directory record Official record
Conditions
PTSD, Post ICU Syndrome
Interventions
Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
Other
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Jun 27, 2026, 12:11 PM EDT
Active, not recruiting Not applicable Interventional Results available

Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome

NCT06238609
View directory record Official record
Conditions
Muscle Atrophy, Muscle Weakness, Blood Flow
Interventions
Intervention Group, Control Group
Device
Lead sponsor
Bijan Najafi, PhD
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 29, 2024 · Synced Jun 27, 2026, 12:11 PM EDT