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ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:51 AM EDT

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Showing 1–24 of 64 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post Operative Pulmonary Complications Clear all
Terminated Phase 3 Interventional

Inhaled Nitric Oxide in Prevention/Treatment of Ischemia-Reperfusion Lung Injury Related to Lung Transplantation

NCT00060450
View directory record Official record
Conditions
Ischemia-Reperfusion Injury
Interventions
nitric oxide for inhalation, Placebo
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional

Live Music Therapy to Reduce Anxiety, Pain and Improve Sleep in Post-Operative Lung Transplant Patients: a Pilot Study

NCT04975607
View directory record Official record
Conditions
Lung Transplant; Complications
Interventions
Music Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Phase 4 Interventional Results available

Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery

NCT02635542
View directory record Official record
Conditions
Neuromuscular Blockade, Postoperative Complications
Interventions
Succinylcholine, Cisatracurium
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Jul 22, 2026, 12:51 AM EDT
Completed No phase listed Observational Results available

Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19

NCT04397939
View directory record Official record
Conditions
COVID-19, Myocardial Reperfusion Injury, Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Not listed
Enrollment
4,695 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Phase 2 Interventional Results available

Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation

NCT00224406
View directory record Official record
Conditions
Ischemia-Reperfusion Injury, Lung Transplantation
Interventions
Repertaxin, Placebo
Drug · Other
Lead sponsor
Dompé Farmaceutici S.p.A
Industry
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
5
States / cities
Los Angeles, California • Denver, Colorado • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Jul 22, 2026, 12:51 AM EDT
Enrolling by invitation Not applicable Interventional

Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study

NCT07277244
View directory record Official record
Conditions
Robotic Surgery, Post Operative Pulmonary Complications
Interventions
Low Intensity Mechanical Ventilation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 22, 2026, 12:51 AM EDT
Withdrawn No phase listed Observational

Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA

NCT03135691
View directory record Official record
Conditions
Ventilator-Induced Lung Injury
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional Results available

Feasibility of Measuring Volume of Inspiration Via Noninvasive Motion Sensors

NCT06609616
View directory record Official record
Conditions
Postoperative Pulmonary Complications (PPCs)
Interventions
Motion Sensor, Incentive Spirometer
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection

NCT05144828
View directory record Official record
Conditions
Pain, Postoperative, Lung Diseases
Interventions
Intercostal Nerve Cryoablation, Patient-controlled analgesia (PCA)
Device · Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 22, 2026, 12:51 AM EDT
Recruiting No phase listed Observational

Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation

NCT00457847
View directory record Official record
Conditions
Primary Graft Dysfunction, Lung Transplantation
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
15 Years to 65 Years
Enrollment
1,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Phase 4 Interventional Results available

Multicenter Infection Surveillance Study Following Open Heart Surgery

NCT00673712
View directory record Official record
Conditions
Surgery, Pneumonia, Surgical Site Infection
Interventions
Continuous Sternal Block, Opioid based analgesia
Device · Drug
Lead sponsor
Halyard Health
Industry
Eligibility
18 Years and older
Enrollment
647 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
8
States / cities
Birmingham, Alabama • Newark, Delaware • Lexington, Kentucky + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Phase 2 Interventional Results available

Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients

NCT03221764
View directory record Official record
Conditions
Atrial Fibrillation, Lung Transplant; Complications
Interventions
Amiodarone with CoSeal, CO2 driver
Drug · Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 28, 2020 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional Results available

Evaluation of The MetaNeb® System to Reduce Postoperative Pulmonary Complications

NCT02627742
View directory record Official record
Conditions
Atelectasis, Pulmonary Complications
Interventions
MetaNeb® System
Device
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Years and older
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Burlington, Massachusetts • Charlotte, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional

Intraoperative Protective Ventilation and Postoperative Pulmonary Complications

NCT02671721
View directory record Official record
Conditions
Complication of Ventilation Therapy, Postoperative Respiratory Complications
Interventions
Maximal Compliance, Transpulmonary Pressure
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Jul 22, 2026, 12:51 AM EDT
Terminated Phase 2 Interventional Results available

Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction

NCT01715883
View directory record Official record
Conditions
Primary Graft Dysfunction
Interventions
Sodium Nitrite
Drug
Lead sponsor
Gladwin, Mark, MD
Individual
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 31, 2018 · Synced Jul 22, 2026, 12:51 AM EDT
Not listed Not applicable Interventional

Cryoablation of Intercostal Nerves for Post-Operative Pain Management in Opioid-Tolerant Patients

NCT05276258
View directory record Official record
Conditions
Pain, Pain, Postoperative
Interventions
cryoSPHERE Ablation, Bupivacaine
Device · Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional Results available

The Influence of Endotracheal Tube Design on Fluid Leakage Into the Lungs During Surgery

NCT01539135
View directory record Official record
Conditions
Respiratory Aspiration
Interventions
Methylene Blue
Drug
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 12, 2015 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional

PROVHILO:Protective Ventilation During General Anesthesia for Open Abdominal Surgery

NCT01441791
View directory record Official record
Conditions
Postoperative Respiratory Complications
Interventions
Lung protective strategy ventilation
Procedure
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Boston, Massachusetts • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Jul 22, 2026, 12:51 AM EDT
Recruiting No phase listed Observational

Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation

NCT00552357
View directory record Official record
Conditions
Primary Graft Dysfunction, Lung Transplantation
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
13 Years to 68 Years
Enrollment
1,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional

Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer

NCT00363428
View directory record Official record
Conditions
Lung Cancer, Perioperative/Postoperative Complications, Pulmonary Complications, Tobacco Use Disorder
Interventions
exercise intervention, smoking cessation intervention, counseling intervention, educational intervention, conventional surgery, pulmonary complications management/prevention
Behavioral · Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 120 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional Results available

An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study

NCT04108130
View directory record Official record
Conditions
Postoperative Pulmonary Complications
Interventions
Preoperative Education, Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization, Individualization of Neuromuscular Blockade, Postoperative Incentive Spirometry, Postoperative Ambulation
Other · Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
794 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
16
States / cities
San Francisco, California • Stanford, California • Aurora, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jul 22, 2026, 12:51 AM EDT
Not listed Phase 1Phase 2 Interventional

Postoperative Pain Control With Lipossomic Extended Release Bupivacaine

NCT03560362
View directory record Official record
Conditions
Pain, Postoperative, Lung Cancer
Interventions
Bupivacaine liposome, Bupivacaine / Epinephrine
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Jul 22, 2026, 12:51 AM EDT
Completed Not applicable Interventional

Comparison of Pulmonary Function and Efficacy of Different Nerve Block Catheters for Shoulder Surgery

NCT02117778
View directory record Official record
Conditions
Post-Operative Pain
Interventions
Continuous Nerve Block
Procedure
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Jul 22, 2026, 12:51 AM EDT
Withdrawn Not applicable Interventional

Preoperative Self-managed Respiratory Therapy for Reduction of Postoperative Pulmonary Complications

NCT03356496
View directory record Official record
Conditions
Postoperative Respiratory Complication
Interventions
AirLife 4000 cc incentive spirometry device
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced Jul 22, 2026, 12:51 AM EDT