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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post Operative Trauma Clear all
Completed Phase 2 Interventional Results available

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

NCT02554253
View directory record Official record
Conditions
Cognitive Disorders, Delirium, Acute Kidney Injury
Interventions
Ketamine, Propofol
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
75 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Jul 21, 2026, 3:41 PM EDT
Recruiting Phase 2 Interventional

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

NCT04750616
View directory record Official record
Conditions
Ischemia Reperfusion Injury, Myocardial Injury, Acute Kidney Injury
Interventions
Niacinamide, Placebo
Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Phase 4 Interventional Results available

Nasal Decolonization for Orthopedic Trauma Patients

NCT04146116
View directory record Official record
Conditions
Surgical Site Infection
Interventions
intranasal povidone-iodine
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eliminate Risk of Cardiac Surgical Site Events

NCT01425697
View directory record Official record
Conditions
Surgical Site Infections
Interventions
2% Chlorhexidine Gluconate cloths, Standard of Care preoperative preparation.
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
739 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
4
States / cities
Lexington, Kentucky • Ridgewood, New Jersey • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Phase 2 Interventional Results available

Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI

NCT00586820
View directory record Official record
Conditions
Myocardial Reperfusion Injury
Interventions
BQ-123, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Jul 21, 2026, 3:41 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Safety and Efficacy of Perioperative Remodulin® in Orthotopic Liver Transplant Recipients

NCT01884038
View directory record Official record
Conditions
Liver Transplant
Interventions
treprostinil sodium, Placebo
Drug
Lead sponsor
United Therapeutics
Industry
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Jul 21, 2026, 3:41 PM EDT
Not listed Not applicable Interventional

Nerve Block for Pain Control After Fracture Surgery

NCT05391464
View directory record Official record
Conditions
Ankle Fractures, Distal Radius Fracture
Interventions
Peripheral Nerve Block
Procedure
Lead sponsor
MaineGeneral Health
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Augusta, Maine
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Phase 4 Interventional Results available

Exparel for Postoperative Pain Management in Shoulder Surgery

NCT02472314
View directory record Official record
Conditions
Fracture of Shoulder and Upper Arm
Interventions
1.3% Liposomal Bupivacaine, 0.125% Bupivacaine
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Jul 21, 2026, 3:41 PM EDT
Withdrawn Phase 2 Interventional

Transdermal Continuous Oxygen Therapy for Infection Prophylaxis in High- Risk Patients Undergoing Colon Surgery

NCT02617706
View directory record Official record
Conditions
Anorectal Surgeries
Interventions
Epiflo
Device
Lead sponsor
Neogenix, LLC dba Ogenix
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2017 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reduction in IV Associated Contamination

NCT01426217
View directory record Official record
Conditions
Post-operative Infections
Interventions
Passive Bundle PSI (Problem Solving Innovations) Medical HubScrub, PSI Medical DocIt
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
594 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance

NCT03880058
View directory record Official record
Conditions
Scars
Interventions
SLI-F06, Formulation buffer
Drug
Lead sponsor
Scarless Laboratories, Inc.
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Chicago, Illinois • St Louis, Missouri • Bala-Cynwyd, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Not applicable Interventional

Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions

NCT03208478
View directory record Official record
Conditions
Pain, Postoperative, Anterior Cruciate Ligament Injury
Interventions
Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix)
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Jul 21, 2026, 3:41 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Accessible Remote Rehabilitation System for Real-Time Biomechanical Monitoring

NCT07492797
View directory record Official record
Conditions
Hand Injury Rehabilitation, Postoperative Rehabilitation
Interventions
AI-Based Camera Tele-Rehabilitation Monitoring System, Standard Telehealth Rehabilitation
Device · Behavioral
Lead sponsor
Mississippi State University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Jackson, Mississippi • Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Jul 21, 2026, 3:41 PM EDT
Completed No phase listed Observational

Does the Presence of Preoperative Proteinuria Predict Postoperative Acute Kidney Injury in Obese Patients Undergoing Elective Laparoscopic Surgery?

NCT02798042
View directory record Official record
Conditions
Acute Kidney Injury, Obesity, Proteinuria
Interventions
Urine Sample
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
1,434 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Phase 3 Interventional Results available

D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection

NCT04233424
View directory record Official record
Conditions
Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
Interventions
D-PLEX, Standard of Care (SoC)
Drug
Lead sponsor
PolyPid Ltd.
Industry
Eligibility
18 Years to 99 Years
Enrollment
977 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Sheffield, Alabama • Los Angeles, California • Redding, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jul 21, 2026, 3:41 PM EDT
Withdrawn Not applicable Interventional

Spine and Tumor Screening and Supplementation

NCT03660540
View directory record Official record
Conditions
Spinal Injuries, Sarcoma, Nutritional Deficiency
Interventions
Juven
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Jul 21, 2026, 3:41 PM EDT
Active, not recruiting Not applicable Interventional

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

NCT07498166
View directory record Official record
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)

NCT02296645
View directory record Official record
Conditions
Surgical Site Infection
Interventions
ZuraPrep, ChloraPrep
Drug
Lead sponsor
Zurex Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Sterling, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery

NCT04957342
View directory record Official record
Conditions
Pain, Postoperative, Gingival Diseases
Interventions
amnion-chorion membrane, Sutures
Device · Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Jul 21, 2026, 3:41 PM EDT
Completed No phase listed Observational Results available

Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19

NCT04397939
View directory record Official record
Conditions
COVID-19, Myocardial Reperfusion Injury, Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Not listed
Enrollment
4,695 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Post-Operative Quality of Life Evaluation for Different Anesthesia Techniques for Arthroscopic Shoulder Surgery

NCT01355757
View directory record Official record
Conditions
Rotator Cuff Injury
Interventions
Baxter INFUSOR System, Single Injection of Local Anesthetic
Device · Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2014 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Not applicable Interventional Results available

A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications

NCT03134209
View directory record Official record
Conditions
Joint Disease, Arthropathy
Interventions
Zipper surgical skin closure, Monocryl + Dermabond, Polyester mesh + Dermabond
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Jul 21, 2026, 3:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs

NCT01383239
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Immediate Postoperative Therapy, Delayed Physical Therapy
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 100 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
9
States / cities
San Francisco, California • Boulder, Colorado • Iowa City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Jul 21, 2026, 3:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery

NCT05210556
View directory record Official record
Conditions
Surgical Site Infection, Surgical Complication, Gynecologic Cancer
Interventions
Diagnosed with Surgical Site Infection
Other
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jul 21, 2026, 3:41 PM EDT