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Conditions: Hypertensive Disorder
Interventions: Blood pressure cuff; Device
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years to 54 Years · Female only
Enrollment: 421 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Hypertension, Pregnancy-Induced
Interventions: Acetaminophen, Ibuprofen; Drug
Lead sponsor: MemorialCare Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Preeclampsia Severe, Preeclampsia Postpartum
Interventions: Ibuprofen 600 mg, Ketorolac, Acetaminophen, Oxycodone; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: Female only
Enrollment: 287 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Interventions: Heart Health Doula Intervention Program, Usual Care; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 454 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions: Metformin, Esomeprazole; Drug
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension
Interventions: Video, Text Reminder, Blood pressure threshold; Other
Lead sponsor: Ochsner Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 296 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression, Patient Empowerment, Patient Education, Postpartum Care
Interventions: Video Education; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Pregnancy, Preeclampsia
Interventions: abbreviation of magnesium sulfate therapy (12 hours versus the traditional 24 hours after delivery); Drug
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pre-Eclampsia, Pregnancy Induced Hypertension
Interventions: Not listed
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 1,100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: San Diego, California

Conditions: Preeclampsia, Preeclampsia Postpartum, Preeclampsia Severe or Mild
Interventions: Butterfly iQ3 ultrasound system for determination of postpartum volume status, Oral furosemide, Intravenous furosemide; Diagnostic Test · Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Orange, California

Conditions: Preeclampsia
Interventions: Compound 21, Angiotensin II; Drug
Lead sponsor: Anna Stanhewicz, PhD; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Preeclampsia, Gestational Hypertension, Hypertension, Obesity, Overweight and Obesity, Pregnancy Complications, Pregnancy Toxemia, Postpartum Preeclampsia
Interventions: Home Blood Pressure Monitoring, Heart Health 4 New Moms, Usual care; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertension
Interventions: Pulsewave oscillometric wrist cuff blood pressure monitor; Device
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2016
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication, Postpartum Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Morbidity, Morbidity;Perinatal
Interventions: BP Watch; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Preeclampsia, Gestational Hypertension, Superimposed Preeclampsia, Chronic Hypertension in Obstetric Context
Interventions: Ibuprofen 600 mg, Standard Postpartum Care without NSAIDs; Drug · Other
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Preeclampsia, Preeclampsia Severe, Preeclampsia Mild, Preeclampsia Postpartum
Interventions: Illustration based application, Text based application; Other
Lead sponsor: MemorialCare Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Hypertension in Pregnancy, Postpartum Preeclampsia, Postpartum Complication
Interventions: RI-SPHERES, Standard self-measured blood pressure program; Behavioral
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 1,536 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 5
States / cities: Newport, Rhode Island • Providence, Rhode Island • Wakefield, Rhode Island + 2 more

Conditions: Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia, Cardiovascular Complication
Interventions: Placebo, Dapagliflozin 10mg Tab; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Preeclampsia
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 13 Years to 45 Years · Female only
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Post Partum Pre-eclampsia
Interventions: no intervention; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: New York, New York • Durham, North Carolina

Conditions: Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension, Eclampsia; Complicating Pregnancy
Interventions: MFeast ENHANCED, MFeast Usual Care; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hypertension, Postpartum Preeclampsia
Interventions: Nifedipine and Enalapril, Nifedipine and Labetalol; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
Interventions: Web-based educational and motivational modules, Information and Screening Group; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 151 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pre-Eclampsia, Gestational Hypertension, Sleep
Interventions: SNOO, Safe sleep education in the postpartum period; Device · Other
Lead sponsor: Alisse Hauspurg; Other
Eligibility: 18 Years and older · Female only
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

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Use of a Cloud-connected Remote Blood Pressure Monitoring Program During the Postpartum Period for Hypertensive Women

Hypertension In Postpartum Preeclampsia Study

Preeclampsia And Nonsteroidal Drugs for Analgesia: a Randomized Non Inferiority Trial

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

Metformin and Esomeprazole in Preterm Pre-eclampsia

Remote Postpartum Blood Pressure Monitoring and Cardiovascular Education

Postpartum Video Education

Abbreviated MgSO4 Therapy in Post-partum Preeclampsia

Multi-Omics for Maternal Health After Preeclampsia

Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound

Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia

Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia

Validation of Pulsewave Blood Pressure Monitor in Hypertensive and Normotensive Pregnant and Postpartum Women

Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines

Postpartum NSAIDS and Maternal Hypertension

Preeclampsia Educational Program Study (PrEPS)

Rhode Island - Statewide Postpartum Hypertension Remote Surveillance

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)

Characterization and Epigenetics of Post-Partum Preeclampsia

Nutrition Optimization and Community Upliftment for Postpartum Recovery: Hypertension

Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia

Neonatal Sleep Intervention to Improve Postpartum Hypertension