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ClinicalTrials.gov public records Last synced Oct 3, 2026, 2:32 PM EDT

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Showing 49–72 of 1,620 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post Traumatic Stress Disorder (PTSD) Clear all
Not listed Phase 1 Interventional Accepts healthy volunteers

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

NCT05894902
View directory record Official record
Conditions
Major Depression, Post Traumatic Stress Disorder
Interventions
SM-001
Drug
Lead sponsor
Advanced Integrative Medical Science Institute
Other
Eligibility
25 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional Results available

Trauma Informed Guilt Reduction Therapy

NCT02512445
View directory record Official record
Conditions
Guilt, Shame, Post-traumatic Stress Disorders
Interventions
Trauma Informed Guilt Reduction Therapy, Supportive Care Therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
3
States / cities
San Diego, California • Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 9, 2025 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Dismantling Exposure, Relaxation, and Rescripting Therapy

NCT02236377
View directory record Official record
Conditions
Frequent Trauma-related Nightmares
Interventions
Exposure, Relaxation, and Rescripting Therapy
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 3, 2026, 2:32 PM EDT
Recruiting Not applicable Interventional

Enhancing Memory in Cognitive Processing Therapy for PTSD

NCT06000475
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive Processing Therapy, Cognitive Processing Therapy (CPT) + Memory Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study

NCT00880152
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression
Interventions
Mindfulness-based stress reduction
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 24, 2010 · Synced Oct 3, 2026, 2:32 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Can Exercise Improve Therapeutic Learning Among Women With Posttraumatic Stress Disorder

NCT04417309
View directory record Official record
Conditions
PTSD
Interventions
Experimental, Active Control
Behavioral
Lead sponsor
Thomas Adams
Other
Eligibility
21 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Phase 4 Interventional Results available

Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)

NCT02199652
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Suicidal Ideation, Nightmares
Interventions
Prazosin, Placebo
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2018 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional Results available

Mobile Self-Tracking of Mental Health

NCT05023252
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder, Schizoaffective Disorder, Post-traumatic Stress Disorder
Interventions
mobile application
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD

NCT02290847
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Cognitive Processing Therapy (cognitive only version; CPT-C)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 3, 2026, 2:32 PM EDT
Terminated Phase 2 Interventional

Cognitive REmediation After Trauma Exposure Trial = CREATE Trial

NCT01416948
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Methylphenidate Hydrochloride 20 mg, Placebo Capsule, Galantamine 12 mg
Drug
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
7
States / cities
San Diego, California • Boston, Massachusetts • Manchester, New Hampshire + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Phase 1 Interventional Results available

Improving Functional Outcomes of Veterans With PTSD and Tobacco Dependence

NCT02576899
View directory record Official record
Conditions
Tobacco, Posttraumatic Stress Disorder
Interventions
Acceptance and Commitment Therapy for PTSD and Tobacco Use, Freedom From Smoking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2020 · Synced Oct 3, 2026, 2:32 PM EDT
Not yet recruiting No phase listed Observational

Exploring Clinical Study Experiences of People With Post Traumatic Stress Disorder

NCT06146049
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Power Life Sciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Oct 3, 2026, 2:32 PM EDT
Completed No phase listed Observational

The Trauma Recovery and Resiliency Research Project

NCT00131534
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Individual therapy, Group therapy
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 65 Years
Enrollment
969 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 2012
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 3, 2026, 2:32 PM EDT
Recruiting Phase 3 Interventional

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

NCT07226232
View directory record Official record
Conditions
Major Depression
Interventions
Psilocybin
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
5
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Phase 2 Interventional Results available

Phase II Study of BNC210 in PTSD

NCT02933606
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
BNC210, Placebo
Drug
Lead sponsor
Bionomics Limited
Industry
Eligibility
18 Years to 70 Years
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
20
States / cities
Oceanside, California • Rancho Mirage, California • Redlands, California + 17 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 3, 2026, 2:32 PM EDT
Not yet recruiting Not applicable Interventional

A Transdiagnostic Sleep Health Intervention for Veterans With PTSD

NCT06549049
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
Interventions
TranS-C for PTSD, Sleep Psychoeducation Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders

NCT02322047
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder (PTSD)
Interventions
Prazosin, Naltrexone, Placebo (Prazosin), Placebo (Naltrexone)
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 29, 2020 · Synced Oct 3, 2026, 2:32 PM EDT
Completed No phase listed Observational

The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels

NCT01385709
View directory record Official record
Conditions
Bipolar Affective Disorders, Cyclothymic Disorder, Schizoaffective Disorder, Major Depressive Disorder, Dysthymic Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder, Premenstrual Dysphoric Disorder, Social Anxiety Disorder
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

NCT00118534
View directory record Official record
Conditions
Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions
Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
943 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
11
States / cities
Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Pilot Study of PRX-03140 to Assess Safety for Use in Adult Subjects With Post Traumatic Stress Disorder

NCT01492699
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
PRX-03140
Drug
Lead sponsor
Alachua Government Services, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Oct 3, 2026, 2:32 PM EDT
Recruiting Phase 2 Interventional

Mindfulness-based Psilocybin Therapy for PTSD

NCT07104916
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Depression - Major Depressive Disorder
Interventions
Psilocybin + MBCT therapy, Active Comparator: Psilocybin with Support Only
Combination Product
Lead sponsor
Anthony P King
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional

Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance Dependence

NCT02461732
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Dependence
Interventions
Treatment for Integrated Posttraumatic Stress and Substance Use (TIPSS), Cognitive-Behavioral Therapy for Substance Dependence
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 3, 2026, 2:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses

NCT03132220
View directory record Official record
Conditions
Burn-Out Syndrome, Work-Related Stress Disorder
Interventions
Mindfulness-Based Cognitive Therapy, Book Club Active Control Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Oct 3, 2026, 2:32 PM EDT
Completed No phase listed Observational

The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study

NCT01040988
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 20 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 3, 2026, 2:32 PM EDT