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ClinicalTrials.gov public records Last synced Oct 12, 2026, 7:52 AM EDT

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Showing 217–240 of 535 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post Traumatic Stress Symptoms Clear all
Recruiting Not applicable Interventional

Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress

NCT07483333
View directory record Official record
Conditions
Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning, Chronic Medical Conditions, Chronic Medical Condition, Chronic Medical Illness, Posttraumatic Stress Disorder PTSD, Posttraumatic Stress Disorders, Posttraumatic Stress Symptoms, Posttraumatic Stress
Interventions
Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual, Structured Psychotherapy for Adolescents Responding to Chronic Stress - Individual
Behavioral
Lead sponsor
Anthony Vesco
Other
Eligibility
8 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional

The Mobile PTSD Coach App in Acute Injury Survivors

NCT03247179
View directory record Official record
Conditions
Chronic Pain, Acute Pain Due to Trauma, Posttraumatic Stress Disorder
Interventions
PTSD Coach mobile application
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional Results available

Integrated Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)

NCT00127413
View directory record Official record
Conditions
Pain, Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy - Pain, Cognitive Behavioral Therapy-Integrated, Cognitive Processing Therapy - PTSD, Treat as Usual
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2015 · Synced Oct 12, 2026, 7:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era

NCT00958061
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Depression, Diabetes, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Female only
Enrollment
4,219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Charleston, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 12, 2026, 7:52 AM EDT
Recruiting Not applicable Interventional

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

NCT06538246
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder, Stress, Worries; Pain or Disability, Breath Shortness
Interventions
Blueprint, Education program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional

MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence

NCT05106361
View directory record Official record
Conditions
Intimate Partner Violence, Depression, Post Traumatic Stress Disorder
Interventions
MOSAIC Plus, MOSAIC
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Not listed Not applicable Interventional

Addressing Traumatic Stress Symptoms in Children

NCT03334942
View directory record Official record
Conditions
Violence, Non-accidental, Posttraumatic Stress Disorder, Parent-Child Relations, Assault, Youth
Interventions
Child and Family Traumatic Stress Intervention
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional

Feasibility and Efficacy of A Yoga Intervention for Comorbid Chronic Pain and PTSD

NCT06123065
View directory record Official record
Conditions
PTSD, Chronic Pain
Interventions
Yoga
Behavioral
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Phase 3 Interventional

Alternative Support for Rural and Isolated Women in an HMO

NCT00186212
View directory record Official record
Conditions
Stress Disorders, Post-traumatic, Depression, Breast Cancer
Interventions
workbook/journal on coping with breast cancer, standard educational materials on breast cancer
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2011 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Phase 3 Interventional

ICU Family Communication Study

NCT00720200
View directory record Official record
Conditions
Depression, Depressive Symptoms, Anxiety, Stress Disorders, Post-Traumatic, ICU Hospitalization, Care and Treatment in ICU
Interventions
Facilitator-Based intervention, Usual Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
Renton, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Oct 12, 2026, 7:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Military Service and Family Members for Post Concussive and Posttraumatic Stress Symptoms

NCT03191357
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
n/a observational
Other
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
424 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 12, 2026, 7:52 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

NCT07288593
View directory record Official record
Conditions
Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions
NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment)
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 62 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Not listed Not applicable Interventional

Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)

NCT04121884
View directory record Official record
Conditions
Depressive Symptoms, Stress Disorder, Acute, Prolonged Grief Disorder, Alcohol Abuse, Stress Disorders, Post-Traumatic
Interventions
Accelerated Resolution Therapy
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans

NCT01510834
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
Interventions
Multibehavioral, Computerized Tailored Intervention STR2IVE
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
3
States / cities
Honolulu, Hawaii • Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 12, 2026, 7:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

NCT01194661
View directory record Official record
Conditions
Traumatic Brain Injury, Stroke, Headache, PTSD
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 40 Years
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 12, 2026, 7:52 AM EDT
Not yet recruiting Not applicable Interventional

Enhancing Mental and Physical Health of Women Veterans 3.0

NCT07356479
View directory record Official record
Conditions
Cardiovascular Diseases, Overweight, Obesity, Hypertension, Cholesterol, Diabetes Mellitus, Prediabetic State, Menopause, Cognitive Behavioral Therapy, Primary Health Care, Stress Disorders, Post-Traumatic, Prevention, Implementation Science, Quality Improvement
Interventions
EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Recruiting Phase 2 Interventional

HBOT Effects on First Responders' Cognition and Well-Being

NCT07852728
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Completed No phase listed Observational Results available

Regional Anesthesia Military Battlefield Pain Outcomes Study

NCT00431847
View directory record Official record
Conditions
Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder, Substance Abuse
Interventions
Regional Anesthesia, Standard Pain Management Protocol
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
3
States / cities
Bethesda, Maryland • Philadelphia, Pennsylvania • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional Results available

Yoga and Mantram for Chronic Pain and PTSD

NCT03816007
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Chronic Low Back Pain, Chronic Neck Pain
Interventions
Yoga and Mantram Repetition, Veteran Calm
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional

Impact of Cognitive Behavioral Therapy on PTSD-CVD Link

NCT06429293
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive processing therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Active, not recruiting Phase 2 Interventional

Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms

NCT07316088
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
OTX-601 Digital Therapeutic, OTX-003 Comparator app
Device
Lead sponsor
Oui Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans

NCT00691626
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Sleep Disorders, Nightmares
Interventions
CBT for Insomnia plus Imagery Rehearsal, CBT for Insomnia plus psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 12, 2026, 7:52 AM EDT
Terminated Not applicable Interventional

Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy

NCT04763330
View directory record Official record
Conditions
Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
Interventions
Enhanced Usual Care (EUC), Problem Solving Therapy (PST) plus EUC
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Palo Alto, California • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 12, 2026, 7:52 AM EDT
Completed Not applicable Interventional

Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder

NCT02990793
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive Symptoms
Interventions
Active MeRT Treatment, Sham MeRT Treatment
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
18 Years to 65 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Costa Mesa, California • Long Beach, California • San Diego, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 12, 2026, 7:52 AM EDT