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Showing 25–39 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post-Intensive Care Syndrome Clear all
Completed Not applicable Interventional Results available

Psychological Symptoms and Families of COVID-19 Patients

NCT04501445
View directory record Official record
Conditions
Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
Interventions
Written Summary of Rounds
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 23, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Intensive Care Unit (ICU) Diary Project

NCT04305353
View directory record Official record
Conditions
PTSD, Post ICU Syndrome
Interventions
Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
Other
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Sep 23, 2026, 5:02 PM EDT
Not listed No phase listed Observational

Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors

NCT05999903
View directory record Official record
Conditions
Delirium, Critical Illness, Drive
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
40 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 23, 2026, 5:02 PM EDT
Active, not recruiting No phase listed Observational

Addressing Post-Intensive Care Syndrome Among Survivors of COVID (APICS-COVID)

NCT03738774
View directory record Official record
Conditions
Post Intensive Care Syndrome
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
5
States / cities
Baltimore, Maryland • Boston, Massachusetts • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 23, 2026, 5:02 PM EDT
Recruiting Not applicable Interventional

Telehealth-enhanced Patient-oriented Recovery Trajectory After Intensive Care

NCT06014931
View directory record Official record
Conditions
Post-intensive Care Syndrome
Interventions
Telemedicine ICU Recovery Clinic Visit
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
45 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 23, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Pilot Testing PICTURE-THIS

NCT06086301
View directory record Official record
Conditions
Post-intensive Care Syndrome, Transitional Care, Critical Care, Health Services
Interventions
PICTURE-THIS, Enhanced Usual Care, Run-In Phase
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 23, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Improving Outcomes in PICS With Home-Based Program of Rehabilitation and Health Coaching

NCT06184308
View directory record Official record
Conditions
Post-Intensive Care Syndrome
Interventions
Home-based Physical Rehabilitation, Health Coaching
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 23, 2026, 5:02 PM EDT
Completed No phase listed Observational

Muscle Dysfunction in Critical Illness

NCT03717831
View directory record Official record
Conditions
Critical Illness, Intensive Care (ICU) Myopathy, PICS, Muscle Weakness
Interventions
Observational study of standard of care
Other
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
66 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Sep 23, 2026, 5:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

NCT05357170
View directory record Official record
Conditions
Sepsis, Trauma Injury
Interventions
Human feces collection
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 110 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 23, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19

NCT04412330
View directory record Official record
Conditions
Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
Interventions
ICU Recovery + Physical Therapy
Other
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Sep 23, 2026, 5:02 PM EDT
Not listed Not applicable Interventional

Peer Support for Post Intensive Care Syndrome Self-Management

NCT03788096
View directory record Official record
Conditions
Critical Illness, Sepsis, Shock, Septic, Shock, Respiratory Failure, Respiratory Distress Syndrome, Adult, Shock, Hypovolemic, Chronic Disease
Interventions
Peer Support with Motivational Interviewing, Usual Care Group
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Sep 23, 2026, 5:02 PM EDT
Active, not recruiting Not applicable Interventional

Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes

NCT02509520
View directory record Official record
Conditions
Muscle Weakness, Critical Illness, Sarcopenia
Interventions
MPR and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Dietary Supplement
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
45 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 23, 2026, 5:02 PM EDT
Completed No phase listed Observational

Observational Study of Expected ARF Recovery

NCT03797313
View directory record Official record
Conditions
Acute Respiratory Failure, Post Intensive Care Syndrome
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Baltimore, Maryland • Boston, Massachusetts • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Sep 23, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sensation Awareness Focused Training for Spouses

NCT03129204
View directory record Official record
Conditions
Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder, Sleep Deprivation
Interventions
SAF-T
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Sep 23, 2026, 5:02 PM EDT
Recruiting Not applicable Interventional

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

NCT04989790
View directory record Official record
Conditions
Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 18 Years
Enrollment
1,440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
11
States / cities
Madera, California • Orlando, Florida • Louisville, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 23, 2026, 5:02 PM EDT