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ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:09 AM EDT

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Showing 121–144 of 223 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Natal Depression Clear all
Completed Not applicable Interventional

Baby2Home (B2H) Mobile Health Application

NCT05595486
View directory record Official record
Conditions
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness, Post Partum Depression
Interventions
Baby2Home Mobile Application
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Terminated Not applicable Interventional Results available

Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset

NCT01842542
View directory record Official record
Conditions
Depression, Postpartum
Interventions
NeuroStar Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Neuronetics
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
8
States / cities
Hartford, Connecticut • Gainesville, Florida • Pensacola, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 21, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional

OBWELL: Innovative Psychotherapeutic Intervention to Treat Postpartum Depression

NCT06991166
View directory record Official record
Conditions
Post Partum Depression
Interventions
Cognitive behavioral therapy (CBT) psychotherapy group/telehealth, Interpersonal therapy (IPT) psychotherapy group/telehealth
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional

Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression

NCT06877104
View directory record Official record
Conditions
Depression, Postpartum, Postpartum Care
Interventions
Healing @ Home Program (H@H 2.0)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LaPPS: Labor Podcast for Patient Satisfaction

NCT04933708
View directory record Official record
Conditions
Labor Onset and Length Abnormalities, Pregnancy Related
Interventions
Labor Podcast
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional

Family Nurture Intervention in the NICU at The Valley Hospital

NCT03267043
View directory record Official record
Conditions
Premature Birth, Obstetric Labor, Premature
Interventions
Family Nurture Intervention (FNI), Standard Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Ridgewood, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional Results available

Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk

NCT06276647
View directory record Official record
Conditions
Maternal Behavior, Postpartum Depression
Interventions
HOME
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Can Oxytocin Level Predict Postpartum Depression?

NCT02020148
View directory record Official record
Conditions
Postpartum Depression
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 21, 2026, 12:09 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Clinical Validation of a Predictive Test for Postpartum Depression

NCT06831968
View directory record Official record
Conditions
Postpartum Depression (PPD), Pregnancy
Interventions
Enlighten
Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Charlottesville, Virginia • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CSE v. Epidural for Postpartum Depression

NCT03022526
View directory record Official record
Conditions
Depression, Postpartum, Labor Pain
Interventions
CSE, Epidural, Bupivacaine / fentaNYL
Procedure · Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Clinician Managed Interpersonal Psychotherapy

NCT00043602
View directory record Official record
Conditions
Depression, Depression, Postpartum
Interventions
Standard interpersonal psychotherapy (IPT), Clinician managed interpersonal psychotherapy (CM-IPT)
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2007
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 26, 2013 · Synced Oct 21, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ROSE in Sunset Park

NCT04940585
View directory record Official record
Conditions
Post Partum Depression
Interventions
ROSE Program
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression

NCT01463202
View directory record Official record
Conditions
Contraception, Postpartum Depression, Lactation
Interventions
Depot medroxyprogesterone acetate
Drug
Lead sponsor
Beatrice Chen
Other
Eligibility
18 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 21, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional

Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms

NCT07485036
View directory record Official record
Conditions
Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
Interventions
Contingency Management & Problem Solving Therapy, Usual Care
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional Results available

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms

NCT04045132
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations
Interventions
Social Media-Based Parenting Program, MoodGym
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months

NCT02221895
View directory record Official record
Conditions
Pregnancy, Breastfeeding, Contraception, Cervical Cancer, Postpartum Depression
Interventions
Postpartum follow up appointment 2-3 weeks after delivery, Postpartum follow up 6-8wk after delivery
Other
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 50 Years · Female only
Enrollment
344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 21, 2026, 12:09 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Whole-Body Hyperthermia for Mood and Anxiety Disorders

NCT06144294
View directory record Official record
Conditions
Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
Interventions
Whole-Body Hyperthermia, fMRI
Other · Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 21, 2026, 12:09 AM EDT
Completed Not applicable Interventional

Group Therapy for Postpartum Depression

NCT00051246
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Mother-Infant Group Psychotherapy, Interpersonal Psychotherapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 24, 2014 · Synced Oct 21, 2026, 12:09 AM EDT
Terminated Not applicable Interventional Results available

[Study Evaluating the Efficacy and Safety of a Digital Therapeutic as an Adjunct to TAU in Postpartum Depression]

NCT05551195
View directory record Official record
Conditions
Postpartum Depression
Interventions
WB001, ED001
Device
Lead sponsor
Woebot Health
Industry
Eligibility
22 Years to 45 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Lafayette, California • Santa Ana, California • DeLand, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Oct 21, 2026, 12:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Pregnant and Postpartum Women With and Without Mood Disorders

NCT03615794
View directory record Official record
Conditions
Bipolar Disorder, Major Depressive Disorder, Postpartum Depression, Postpartum Psychosis
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Oct 21, 2026, 12:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fresh RX: NHS 2020

NCT04845230
View directory record Official record
Conditions
Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization, Nutrition Deficiency Due to Insufficient Food, Housing Problems, Fetal Complications, Food Deprivation
Interventions
FreshRx Nourishing Healthy Starts
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 21, 2026, 12:09 AM EDT
Terminated Phase 4 Interventional Results available

Postpartum Depression: Transdermal Estradiol Versus Sertraline

NCT00744328
View directory record Official record
Conditions
Postpartum Depression
Interventions
Transdermal Estradiol, Sertraline, Placebo
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 21, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional

Postpartum Care in the NICU (PeliCaN) Transitions

NCT06521398
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Premature Birth, Postpartum Depression, Postpartum Anxiety
Interventions
Doula Support
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
16 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 21, 2026, 12:09 AM EDT