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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Post-Operative Pain Management Clear all
Terminated Phase 4 Interventional Results available

A Study of Loco-Regional Liposomal Bupivacaine Injection

NCT05992896
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Bupivacaine liposome, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Eau Claire, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Local Infiltration Analgesia for Hip Arthroscopy

NCT01454518
View directory record Official record
Conditions
Pain
Interventions
Infiltration of local anesthetic, Normal Saline Injection
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 10, 2013 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Early Phase 1 Interventional

Continuous Femoral Nerve Block With a Tibial Plateau Fracture

NCT02168959
View directory record Official record
Conditions
Tibial Plateau Fracture
Interventions
bupivacaine
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 13, 2016 · Synced Sep 10, 2026, 5:00 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management

NCT05360433
View directory record Official record
Conditions
Post Operative Pain
Interventions
Oxycodone oral capsule
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
19 Years to 40 Years · Female only
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 10, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery

NCT07185425
View directory record Official record
Conditions
Pain, Analgesia, Pregnancy
Interventions
NeuroCuple, Sham
Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional Results available

ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management

NCT00638508
View directory record Official record
Conditions
Postoperative Pain
Interventions
Ketorolac, Ketorolac and Ropivacaine
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Sep 10, 2026, 5:00 PM EDT
Terminated Not applicable Interventional Results available

Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control

NCT01916590
View directory record Official record
Conditions
Post-operative Pain
Interventions
Bupivicaine, placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 31, 2016 · Synced Sep 10, 2026, 5:00 PM EDT
Recruiting No phase listed Observational

Personalized Postoperative Pain Management Following Thoracic Surgery in Adults

NCT05525923
View directory record Official record
Conditions
Thoracic Surgery, Pneumonectomy, Lobectomy, Segmentectomy
Interventions
Not listed
Lead sponsor
OpalGenix, Inc
Industry
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
4
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Not applicable Interventional Results available

Preoperative Gabapentin for Post-tonsillectomy Pain in Children

NCT01707420
View directory record Official record
Conditions
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Interventions
Gabapentin, liquid placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 16 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 3 Interventional Results available

Management of Post-Tonsillectomy Pain in Pediatric Patients

NCT04551196
View directory record Official record
Conditions
Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis
Interventions
Alternating Acetaminophen and Ibuprofen, Combined Acetaminophen and Ibuprofen
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Sep 10, 2026, 5:00 PM EDT
Not yet recruiting Phase 3 Interventional

Phase 3 Bunionectomy Study

NCT07490496
View directory record Official record
Conditions
Postoperative Pain, Bunion
Interventions
CPL-01, saline placebo
Drug
Lead sponsor
Cali Pharmaceuticals LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional Results available

Methadone Versus Morphine for Orthopedic Surgery Patients

NCT00892606
View directory record Official record
Conditions
Fracture, Pain, Postoperative
Interventions
Methadone, Morphine
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

NCT02651324
View directory record Official record
Conditions
Idiopathic Scoliosis, Post-operative Pain
Interventions
Ketamine, Placebo
Drug · Other
Lead sponsor
Albany Medical College
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional

LMX-4 for Postoperative Pain Management in Infants and Children Undergoing Penoplasty Surgery

NCT00847093
View directory record Official record
Conditions
Post-Operative Pain
Interventions
LMX4, LMX4 Placebo
Drug
Lead sponsor
Ferndale Laboratories, Inc.
Industry
Eligibility
3 Months to 3 Years · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2011 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 3 Interventional Results available

Intraoperative Lidocaine Infusion for Postoperative Pain Management in Obese Patients

NCT01944098
View directory record Official record
Conditions
Bariatric Surgical Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional

Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study

NCT06725485
View directory record Official record
Conditions
Postoperative Pain Management
Interventions
Low-Dose Lidocaine
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional Results available

Preoperative Pain Control in Gastric Bypass Surgery Patients

NCT01801189
View directory record Official record
Conditions
Post-operative Pain
Interventions
Pregabalin, Placebo (for Pregabalin)
Drug
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years to 70 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2022 · Synced Sep 10, 2026, 5:00 PM EDT
Recruiting Phase 4 Interventional

Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy

NCT07037888
View directory record Official record
Conditions
Femoracetabular Impingement, Hip Arthroscopy
Interventions
Ketorolac, Control (Standard treatment), Omeprazole
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Music Therapy in the Treatment of Perioperative Anxiety and Pain

NCT05263635
View directory record Official record
Conditions
Pain, Post Operative, Anxiety, Opioid Use
Interventions
Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Sep 10, 2026, 5:00 PM EDT
Terminated No phase listed Interventional Results available

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

NCT05017701
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Bridge device, Sham device
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 10, 2026, 5:00 PM EDT
Not listed Not applicable Interventional

Caffeine Study for Pain Control Following Total Joint Replacement

NCT04280263
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Caffeine, Placebo oral tablet
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Egg Harbor, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 10, 2026, 5:00 PM EDT
Enrolling by invitation Phase 2Phase 3 Interventional

Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion

NCT06350981
View directory record Official record
Conditions
Back Pain, Surgery-Complications, Narcotic Use, Physical Stress, Post Operative Pain
Interventions
Exparel, Bupivacain
Drug
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Not applicable Interventional Results available

Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay

NCT00743730
View directory record Official record
Conditions
Post Operative Pain
Interventions
Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
4 Years to 18 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 10, 2026, 5:00 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Preemptive Analgesia With Celecoxib for Acute Dental Pain Management

NCT04790812
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Celecoxib, Acetaminophen, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 45 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Sep 10, 2026, 5:00 PM EDT