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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:40 PM EDT

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Showing 145–168 of 247 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Partum Depression Clear all
Completed No phase listed Observational

A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy

NCT07047820
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Zuranolone
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years and older · Female only
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Woonsocket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Phase 2 Interventional Results available

Inhaled Oxytocin and HPA Axis Reactivity

NCT03593473
View directory record Official record
Conditions
Depression, Postpartum, Anxiety Disorders, Stress, Psychological
Interventions
Intranasal Oxytocin, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 8, 2025 · Synced Oct 21, 2026, 1:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biological Triggers of Depression in Pregnancy

NCT02566980
View directory record Official record
Conditions
Depression and Suicide, Mood Disorders, Other Perinatal Conditions
Interventions
Not listed
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older · Female only
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 21, 2026, 1:40 PM EDT
Not yet recruiting Not applicable Interventional

Postpartum Care in the NICU Multi-Site

NCT07873190
View directory record Official record
Conditions
Postpartum, Postpartum Depression (PPD), Hypertension Disorders in Pregnancy, Postpartum Anxiety, Postpartum Care, Care Coordination, Care Gaps
Interventions
Postpartum Doula Support in the NICU
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
756 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
14
States / cities
Newark, Delaware • Voorhees Township, New Jersey • Bryn Mawr, Pennsylvania + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression

NCT01379781
View directory record Official record
Conditions
Postpartum Depression
Interventions
Behavioral Intervention for PPD
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PREPP: Preventing Postpartum Depression

NCT03283254
View directory record Official record
Conditions
Postpartum Depression (PPD)
Interventions
Practical Resources for Effective Postpartum Parenting (PREPP), Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 21, 2026, 1:40 PM EDT
Recruiting No phase listed Observational

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

NCT06788977
View directory record Official record
Conditions
Pregnancy, Migraine, Headache, Postpartum, Depression, Anxiety
Interventions
external Trigeminal Nerve Stimulation
Device
Lead sponsor
Cefaly Technology
Industry
Eligibility
18 Years to 44 Years · Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Darien, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Not listed Not applicable Interventional

Translating Research Into Practice for Postpartum Depression

NCT00548743
View directory record Official record
Conditions
Postpartum Depression
Interventions
Screening and follow up, Usual care
Behavioral
Lead sponsor
Olmsted Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2007 · Synced Oct 21, 2026, 1:40 PM EDT
Active, not recruiting Not applicable Interventional

Enhancing Mental and Physical Health of Women Veterans

NCT05050266
View directory record Official record
Conditions
Cardiovascular Diseases, Overweight, Obesity, Smoking, Hypertension, Cholesterol, Diabetes Mellitus, Prediabetic State, Pregnancy, Depression, Postpartum, Prevention, Implementation Science, Quality Improvement, Virtual Care
Interventions
EBQI, REP
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Recruiting No phase listed Observational

A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone

NCT07398469
View directory record Official record
Conditions
Postpartum Depression
Interventions
Zuranolone
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Circumstances, Parenting Techniques, and Infant Development

NCT02121496
View directory record Official record
Conditions
Postpartum Depression, Infant Development, Rhythm; Sleep
Interventions
Resources for Postpartum Parenting
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 21, 2026, 1:40 PM EDT
Recruiting Not applicable Interventional

Accelerated iTBS for Post Partum Depression

NCT03417960
View directory record Official record
Conditions
Post Partum Depression
Interventions
iTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Withdrawn Phase 2Phase 3 Interventional

The Perinatal Synergistic Multi-component Intervention to alLeviate dEpressive Symptoms. A Case Series

NCT06048263
View directory record Official record
Conditions
Postpartum Depression
Interventions
interpersonal psychotherapy (IPT), Ketamine
Behavioral · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional

Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)

NCT00951717
View directory record Official record
Conditions
Depression, Postpartum, Depression
Interventions
Behavioral education intervention
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
590 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2011 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional

A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting Program

NCT06042166
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Parenting Stress, Parent Child Relationships
Interventions
Connecting and Reflecting Experience (CARE) Program
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Mental Health in the Hospital Setting

NCT03777046
View directory record Official record
Conditions
Post Partum Depression
Interventions
Standard of Care (SOC), SOC with Psychology Therapy (CBT)
Behavioral
Lead sponsor
Michelle Lopez
Other
Eligibility
18 Years and older · Female only
Enrollment
545 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional

Postpartum Visit Timing and the Effect on Visit Attendance

NCT05399784
View directory record Official record
Conditions
Postpartum Disorder, Postpartum Depression, Postpartum Weight Retention, Breastfeeding, Satisfaction, Patient, Trust
Interventions
Early postpartum visit, Standard postpartum visit
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
13 Years to 50 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Phase 1 Interventional

Cognitive Behavioral Therapy Delivered Over the Internet for Women With Postpartum Depression

NCT00942721
View directory record Official record
Conditions
Postpartum Depression
Interventions
Web-based CBT for PPD
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Iowa City, Iowa • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 21, 2026, 1:40 PM EDT
Recruiting Not applicable Interventional

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

NCT07223736
View directory record Official record
Conditions
Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions
Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fresh RX: NHS 2020

NCT04845230
View directory record Official record
Conditions
Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization, Nutrition Deficiency Due to Insufficient Food, Housing Problems, Fetal Complications, Food Deprivation
Interventions
FreshRx Nourishing Healthy Starts
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 21, 2026, 1:40 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

NCT06737055
View directory record Official record
Conditions
Sleep, Postpartum Depression, Pregnancy Related, Insomnia, Sleep Deprivation, Sleep Hygiene, Sleep Disturbance
Interventions
Education about behavioral strategies to improve sleep
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional

Nurtured in Nature

NCT04146025
View directory record Official record
Conditions
Postpartum Depression, Pregnancy Related, Environmental Exposure
Interventions
Nature Coach Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Oct 21, 2026, 1:40 PM EDT
Completed Not applicable Interventional Results available

A Wearable Morning Light Treatment for Postpartum Depression

NCT04845347
View directory record Official record
Conditions
Post Partum Depression
Interventions
Bright Light Therapy, Dim Light Therapy
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 1:40 PM EDT
Recruiting Not applicable Interventional

Parents and Babies Pilot

NCT07607613
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression (PPD)
Interventions
Parents and Babies Virtual Group Intervention, Parents and Babies Hybrid Group Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 21, 2026, 1:40 PM EDT