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ClinicalTrials.gov public records Last synced Oct 1, 2026, 9:06 PM EDT

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Showing 25–48 of 65 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Stroke Hemiparesis Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Critical Periods After Stroke Study (CPASS)

NCT02235974
View directory record Official record
Conditions
Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction, Cerebrovascular Disorders
Interventions
Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training, Control
Behavioral
Lead sponsor
MedStar National Rehabilitation Network
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Phase 1Phase 2 Interventional Results available

The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke

NCT03080454
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke, Muscle Spasticity, Upper Extremity Paralysis
Interventions
sham Doublestim, anodal Doublestim
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Spinal Plasticity to Enhance Motor Retraining After Stroke

NCT03645122
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident, Hemiparesis
Interventions
Paired corticospinal-motoneuronal stimulation (PCMS), Sham stimulation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 1, 2026, 9:06 PM EDT
Terminated Not applicable Interventional

Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Severe Post-stroke Hemiparesis

NCT04574973
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
transcranial direct current stimulation, intensive upper extremity motor training
Device · Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 1, 2026, 9:06 PM EDT
Suspended Not applicable Interventional

Improving Arm Function Using Wearable Exoskeletons

NCT05951491
View directory record Official record
Conditions
Hemiparesis; Poststroke/CVA
Interventions
Wearable Shoulder Exoskeleton, Wearable Hand Exoskeleton
Device
Lead sponsor
University of Idaho
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis

NCT05535257
View directory record Official record
Conditions
Upper Extremity Weakness, Stroke
Interventions
Sequential Compression Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Saint Johns, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis

NCT00125658
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Control, Experimental
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 23, 2017 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training

NCT02132520
View directory record Official record
Conditions
Hemiparesis, Stroke
Interventions
rTMS, BCI Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 1, 2026, 9:06 PM EDT
Terminated Not applicable Interventional

Neural Mechanisms of Motor Recovery With Technology Assisted Training

NCT05560867
View directory record Official record
Conditions
Hemiparesis, Stroke Sequelae
Interventions
robot-assisted training
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Phase 2 Interventional Results available

Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke

NCT03592745
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Transcutaneous Vagus Nerve Stimulation (tVNS), Sham Transcutaneous Vagus Nerve Stimulation (tVNS)
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soleus Loading Response During Walking

NCT05436366
View directory record Official record
Conditions
Healthy, Spastic Hemiparesis, Stroke
Interventions
Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
Device
Lead sponsor
Victor H. Duenas
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Wearable Exoskeleton for Functional Arm Training

NCT02726204
View directory record Official record
Conditions
Stroke, Post-Stroke Hemiparesis
Interventions
Gravity Elimination Alone, Path Assistance Alone, Path Assistance and Gravity Elimination
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2018 · Synced Oct 1, 2026, 9:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Transcutaneous Electrical Nerve Stimulation on Post-stroke Patients

NCT06541015
View directory record Official record
Conditions
Hemiplegia and/or Hemiparesis Following Stroke, Anterior Circulation Stroke of Uncertain Pathology
Interventions
InTENSity 10 TENS Stimulator
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 1, 2026, 9:06 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

NCT07153536
View directory record Official record
Conditions
Stroke, Spinal Cord Injuries and Disorders, Hemiparesis After Stroke
Interventions
Spinal Cord Stimulator (Medtronic Inceptiv™ System), Physical Therapy
Device · Other
Lead sponsor
Marco Capogrosso
Other
Eligibility
22 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 1, 2026, 9:06 PM EDT
Recruiting No phase listed Observational

Deconstructing Post Stroke Hemiparesis

NCT05993221
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
Providence VA Medical Center
Federal
Eligibility
18 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors

NCT01029912
View directory record Official record
Conditions
Stroke, Hemiparesis, Lower Extremity Paresis
Interventions
Electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 1, 2026, 9:06 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke

NCT05339893
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
In Motion Rehabilitation Robot
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Phase 3 Interventional Results available

Dysport® Adult Lower Limb Spasticity Follow-on Study

NCT01251367
View directory record Official record
Conditions
Post-stroke Spasticity, Spasticity Post-Traumatic Brain Injury
Interventions
Botulinum toxin type A
Biological
Lead sponsor
Ipsen
Industry
Eligibility
18 Years to 80 Years
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
15
States / cities
Scottsdale, Arizona • Downey, California • Oxnard, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 1, 2026, 9:06 PM EDT
Terminated Not applicable Interventional Results available

Brain Stimulation and Rehabilitation for Adults With Chronic, Severe Arm Motor Impairment After Stroke

NCT03538795
View directory record Official record
Conditions
Stroke, Hemiplegia, Hemiparesis
Interventions
iTBS&eCIMT
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Phase 3 Interventional Results available

Study of Botulinum Toxin and Recovery of Hand Function After Stroke

NCT01422161
View directory record Official record
Conditions
Stroke With Hemiparesis
Interventions
Botulinum Toxin commonly known as BOTOX®, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 1, 2026, 9:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Strategies for Recovery of Dexterity Post Stroke

NCT01977027
View directory record Official record
Conditions
Stroke With Hemiparesis
Interventions
Alternate Hand Training or Affected Hand Training
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional Results available

Altering Activation Patterns Post-stroke

NCT02418949
View directory record Official record
Conditions
Stroke, Muscle Spasticity, Hemiparesis
Interventions
Cyproheptadine, Placebo for Cyproheptadine, Active Movement Practice (AMP), Passive Cyclical Stretching
Drug · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 1, 2026, 9:06 PM EDT
Not yet recruiting Not applicable Interventional

Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors

NCT07000019
View directory record Official record
Conditions
Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
Interventions
CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
Behavioral
Lead sponsor
New York Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 1, 2026, 9:06 PM EDT
Completed Not applicable Interventional

Retraining the Walking Pattern After Stroke

NCT03813342
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Gait training with visual feedback of joint kinematics
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
20 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 1, 2026, 9:06 PM EDT