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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:57 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 716 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Complication Clear all

Conditions: Post-laminectomy Pain Syndrome
Interventions: Gralise®, Placebo; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 80 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Perineal Injury, Pain Vulva, Perineum; Injury
Interventions: Perineal ice packs, medicated witch-hazel pads, and topical benzocaine spray; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Acute Pain
Interventions: CR845, Placebo; Drug
Lead sponsor: Cara Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: POSTOPERATIVE DELIRIUM, POSTOPERATIVE COGNITIVE DECLINE
Interventions: Daridorexant 50 mg, Placebo; Drug · Other
Lead sponsor: University of Rochester; Other
Eligibility: 60 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
Interventions: ropivacaine 0.2%; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Failed Back Surgery Syndrome, Postlaminectomy Syndrome, Postdiscectomy Epidural Fibrosis
Interventions: Lumbar nerve root decompression, Preoperative low-dose external beam radiation; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 80 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2002
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Pain, Pain, Postoperative, Pain, Acute, Surgery
Interventions: Technology Based Intervention Group 1, Technology Based Intervention Group 2; Device
Lead sponsor: Vanessa Olbrecht; Other
Eligibility: 12 Years to 18 Years
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Total Knee Replacement Surgery, Post-operative Pain
Interventions: Suzetrigine, Placebo; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 85 Years
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Erector Spinae Plane Block, Pain Control, Post-Operative Pain, Chronic
Interventions: Intravenous Administration of Lidocaine Post Cardiac Surgery, Administration of Lidocaine Post Cardiac Surgery via ESP Catheter; Drug
Lead sponsor: Archit Sharma; Other
Eligibility: 18 Years to 80 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Surgical Site Infection
Interventions: Wound dressing removal.; Other
Lead sponsor: Albany Medical College; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 602 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: Albany, New York • Niskayuna, New York

Conditions: Urinary Tract Infections
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Postoperative Pain, Delirium, Confusion, Sleep
Interventions: Melatonin, Placebo; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Prostate Cancer, Kidney Cancer, Constipation
Interventions: Polyethylene Glycol 3350; Drug
Lead sponsor: Chad R. Tracy; Other
Eligibility: 30 Years to 100 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Cervical Cancer, Vulvar Cancer
Interventions: Questionnaires; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 111 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
Interventions: D-PLEX, Standard of Care (SoC); Drug · Other
Lead sponsor: PolyPid Ltd.; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 975 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 5
States / cities: Augusta, Georgia • New Orleans, Louisiana • St Louis, Missouri + 2 more

Conditions: Pain, Postoperative, Narcotic Use
Interventions: Melatonin 10 MG, Lactose pill; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 35 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Post-operative Pain
Interventions: Placebo, IV acetaminophen; Drug
Lead sponsor: Aultman Health Foundation; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Canton, Ohio

Conditions: Postoperative Pain
Interventions: Ropivacaine, Lidocaine; Drug
Lead sponsor: Jacques E. Chelly; Other
Eligibility: 18 Years to 80 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Post Surgical Pain, Surgery
Interventions: Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 10 Years to 18 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid Consumption
Interventions: Naproxen, Acetaminophen, oxycodone, Gabapentin; Drug
Lead sponsor: AdventHealth; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Bariatric Surgery Candidate, Postoperative Pain, Postoperative Complications
Interventions: Virtual Reality Immersive Relaxation; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast, Mastectomy, Segmental
Interventions: Not listed
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Colon Cancer, Pancreatic Cancer, Perioperative/Postoperative Complications, Primary Peritoneal Cavity Cancer, Rectal Cancer
Interventions: wound care management; Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Post-operative Complications, Operative Surfaces
Interventions: Not listed
Lead sponsor: Brett Lewellyn; Other
Eligibility: 18 Years to 88 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Orlando, Florida

Search by objective public record fields.

GRASSP: Gralise® for Spine Surgery Pain

Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Daridorexant to Prevent Delirium After Heart Surgery

Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks

Low-Dose Radiation to Prevent Complications of Back Surgery

Biofeedback Based Virtual Reality Intervention to Manage Postoperative Pain

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery

The Effect of Timing of Removal of Wound Dressing on Surgical Site Infection Rate After Cesarean Delivery

Early or Late Foley Removal After Thoracotomy

Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery

Preop Laxatives in Robotic Urologic Surgery

Survey on Lymphedema After Sentinel Lymph Node Biopsy in People With Cervical or Vulvar Cancer

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery

Efficacy of IV Acetaminophen for Pain Management

A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery

Mindfulness Surgical Pain Outcomes

Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity

Postoperative VR for Recovery After Bariatric Surgery

Post-Breast Procedure Pain Syndrome Study

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

Patient Positioning for Hand, Wrist, and Elbow Surgery: Stretcher Versus Operating Room Table