Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:02 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Back Pain, Surgery-Complications, Narcotic Use, Physical Stress, Post Operative Pain
Interventions: Exparel, Bupivacain; Drug
Lead sponsor: Foundation for Orthopaedic Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Post-operative Pain, Acute
Interventions: Adding Magnesium as an adjuvant to the adductor canal Block (ACB) for same-day discharge total knee arthroplasty; Drug
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Pontiac, Michigan

Conditions: Post Operative Pain Control, Narcotic Use, Pelvic Organ Prolapse, Urinary Incontinence , Stress, Surgery
Interventions: Sprix; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Pain, Postoperative, Opioid Use Disorder
Interventions: Patient Engagement Tools, Educational Guide; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pain, Post-operative
Interventions: N1539, Intravenous Placebo; Drug
Lead sponsor: Baudax Bio; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Pasadena, Maryland

Conditions: Pain
Interventions: Fentanyl, Placebo; Drug
Lead sponsor: INSYS Therapeutics Inc; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Phoenix, Arizona • Anaheim, California

Conditions: Analgesia
Interventions: F14 (sustained release celecoxib); Drug
Lead sponsor: Arthritis Innovation Corporation; Industry
Eligibility: 45 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 2
States / cities: Denver, Colorado • San Antonio, Texas

Conditions: Breast Cancer, Breast Cancer Female
Interventions: PVB Protocol, PECS-1, Serratus; Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,507 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Phantom Limb Pain
Interventions: Perineural infusion [continuous peripheral nerve block(s)]; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 4
States / cities: Palo Alto, California • San Diego, California • Bethesda, Maryland + 1 more

Conditions: Post-Operative Pain, Pelvic Organ Prolapse
Interventions: Continuous bupivacaine analgesia infusion (ON-Q PainBuster Post-Op Pain Relief System); Device
Lead sponsor: St. Luke's Hospital, Kansas City, Missouri; Other
Eligibility: 18 Years and older · Female only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Shoulder Pain, Postoperative Pain
Interventions: Bupivacaine liposome, Bupivacaine Hydrochloride; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pain, Postoperative, Bunion
Interventions: COV155, placebo; Drug
Lead sponsor: Mallinckrodt; Industry
Eligibility: 18 Years and older
Enrollment: 406 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 5
States / cities: Anaheim, California • Pasadena, California • Pasadena, Maryland + 2 more

Conditions: Spinal Fusion
Interventions: Dexamethasone injection, Saline injection; Drug · Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 10 Years to 18 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Opioid Use, Pain, Postoperative
Interventions: Methadone, Fentanyl, Hydromorphone, Morphine, Sufentanil; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 907 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Hip Disease, Postoperative Pain
Interventions: Erector spinae block, Local block; Procedure
Lead sponsor: Carilion Clinic; Other
Eligibility: 13 Years to 50 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Uterine Cramps, Postoperative Pain Management, Hysteroscopy
Interventions: Magnesium sulfate, Ketamine, Placebo; Drug
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing, Postsurgical Recovery
Interventions: Perioperative photobiomodulation light therapy; Other
Lead sponsor: Elixir MD Inc; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Irvine, California

Conditions: Back Pain, Spinal Stenosis, Spondylosis, Spondylolisthesis, Back Injury
Interventions: Acceptance and Commitment Therapy; Behavioral
Lead sponsor: Samantha Meints; Other
Eligibility: 22 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Chestnut Hill, Massachusetts

Conditions: Spinal Fusion, Chronic Lower Back Pain
Interventions: Laser Diode Brace, Sham Laser Diode Brace; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Postoperative Pain, Anxiety Postoperative, Opioid Use
Interventions: Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG, Essence Olfactory Necklace, Bedside Olfaction Device; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Degenerative Arthritis and Postoperative Pain
Interventions: Placebo, Gapabentin; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 70 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Pain, Postoperative, Chronic Pain, Pain Catastrophizing, Pain, Acute
Interventions: Online mindfulness-based cognitive therapy, Online standardized education; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
Interventions: Interscalene Catheter, Exparel Single Shot Interscalene Block; Procedure
Lead sponsor: Melinda Seering; Other
Eligibility: 18 Years to 90 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Thyroidectomy, Parathyroidectomy, Opioid Use, Pain, Postoperative
Interventions: Quality improvement bundle; Other
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Houston, Texas

Search by objective public record fields.

Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion

Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial

Sprix for Postoperative Pain Control Following Gynecologic Surgery

Patient Engagement in Perioperative Pain Management Project

Placebo-Controlled Evaluation of N1539 Following Bunionectomy Surgery

Fentanyl Sublingual Spray for the Treatment of Moderate to Severe Post-Operative Pain

Safety of F14 Following Total Knee Replacement

Study of Nerve Block Pain Management in Patients Undergoing a Double Mastectomy With Immediate Reconstruction

Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Post-Operative Pain Control Using Direct Continuous Bupivacaine Infusion After Pelvic Organ Prolapse Repair

Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Arthroscopic Shoulder Surgery

Safety and Efficacy Study of COV155 for Post-operative Bunionectomy Pain

Spinal Fusions Steroid Study

Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

Evaluating the Efficacy of Erector Spinae Block in Routine Hip Arthroscopy

Magnesium and Cramping

Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use

Perioperative ACT for Preventing CPSP

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery

Effect of Gabapentin on Orthopedic Pain

Online Mindfulness-based Intervention to Prevent Chronic Pain

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

Opioid Use After Thyroid and Parathyroid Surgeries