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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Pain
Interventions: IV ibuprofen, Ketorolac; Drug
Lead sponsor: Cumberland Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 4
States / cities: Fort Lauderdale, Florida • Chicago, Illinois • Tupelo, Mississippi + 1 more

Conditions: Post Operative Pain
Interventions: 0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure, 0.25% bupivicaine will be injected into the port site prior to closure; Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain, Liver Transplant
Interventions: NSS-2 BRIDGE, Sham NSS-2 BRIDGE; Device
Lead sponsor: Jacques E. Chelly; Other
Eligibility: 18 Years and older
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 4
States / cities: Pittsburgh, Pennsylvania

Conditions: Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local
Interventions: 0.2% ropivacaine local anesthetic continuous erector spinae plane block, 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block, Spinal Morphine; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: San Diego, California

Conditions: Opioid Use, Pain, Post Operative
Interventions: nCAP Signal Relief Patch, Standard of Care; Device · Other
Lead sponsor: Jacques E. Chelly; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Pain
Interventions: Bupivacaine, Clonidine, Morphine; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 4 Years to 16 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Chronic Ocular Pain
Interventions: SAF312 Placebo, SAF312; Other · Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 24
States / cities: Mission Hills, California • Newport Beach, California • Palo Alto, California + 19 more

Conditions: Post Operative Pain
Interventions: OPIOID, NON-OPIOID; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 99 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 5
States / cities: Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more

Conditions: Extremity Injury
Interventions: Rigid Splint, Soft Dressing; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity
Interventions: EXPAREL, On-Q Pain Ball; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Pain, Postoperative, Opioid Use
Interventions: Perioperative Pain Management Education and Counseling; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 14 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pain, Postoperative
Interventions: Exparel; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Postoperative Pain
Interventions: Morphine Sulfate; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
Interventions: 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 15 Years to 35 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Rotator Cuff Tears, Postoperative Pain, Opioid Use
Interventions: Exparel Injectable Solution, Bupivacaine Injectable Solution; Drug
Lead sponsor: Cooper Norcross Health; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Camden, New Jersey

Conditions: Colorectal Disorders, Anorectal Disorder, Patient Satisfaction, Pain, Postoperative, Opioid Use, Opioid Abuse, Opioid Dependence
Interventions: ReCOVER Enhanced Recovery Protocol; Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Popliteal Nerve Block, Foot Surgery, Ankle Surgery, Popliteal Bifurcation
Interventions: Catheter Placed At Bifurcation, Catheter Placed 5cm Above Bifurcation; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: San Diego, California

Conditions: Thoracic Surgery, Chronic Pain, Transcranial Magnetic Stimulation, Neuromodulation
Interventions: active TMS, sham TMS; Device
Lead sponsor: Emine Bayman; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
Interventions: Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pain Management
Interventions: BreEStim, EStim; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Hypotension, Pain
Interventions: Ropivacaine, Epinephrine; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Pain, Anxiety
Interventions: Jazz music, No music; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Pain, Postoperative
Interventions: Bupivacaine; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Pain, Postoperative, Pain, Acute, Pain, Chest, Pain, Satisfaction, Patient, Opioid Use, Unspecified, Opioids; Harmful Use
Interventions: 0.25% Bupivacaine; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy

Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery

Comparison of Low-dose Epidural With Intravenous Narcotic Versus Intravenous Narcotic Alone

Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)

Opioid Analgesic Reduction Study (OARS) - Pilot

Upper Extremity Post-op Splints: Do They Improve Post-operative Pain?

Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball

Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction

Post C-Section Pain Control Using EXPAREL

Intrathecal Morphine for Cesarean Delivery

Lidocaine Versus Bupivacaine in Orthognathic Surgery

The Effect of Liposomal Bupivacaine Nerve Block (Exparel) in Rotator Cuff Surgery

A Multimodal Enhanced Recovery Program in Anorectal Surgery

Continuous Popliteal Nerve Blocks: Effect of Perineural Catheter Tip Location Relative to the Sciatic Nerve Bifurcation on Postoperative Analgesia

Transcranial Magnetic Stimulation (TMS) for Thoracic Surgery

Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery

A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)

The Prevention of Hypotension After Epidural Analgesia After Major Surgery

The Effect of Jazz on Postoperative Pain and Stress in Patients Undergoing Elective Hysterectomy

Injection of Local Anesthetic to Trocar Insertion Sites After Laparoscopy

Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement