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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Pain, Postoperative
Interventions: Fentanyl, Naltrexone; Drug
Lead sponsor: Incline Therapeutics, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Pain, Postoperative, Brachial Plexus Block
Interventions: Bupivacaine HCl, Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain, Postoperative
Interventions: Pain Scale, Exparel Injectable Product, Bupivacaine Injection; Other · Drug
Lead sponsor: Ochsner Health System; Other
Eligibility: 18 Years to 75 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation, Stenosis, Spondylolisthesis, Spondylolysis, Deformity of Spine
Interventions: Exparel, Bupivacaine; Drug
Lead sponsor: Virtua Health, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Mount Holly, New Jersey

Conditions: Pain
Interventions: Placebo acupuncture, Battlefield Acupuncture; Other
Lead sponsor: Mike O'Callaghan Military Hospital; Federal
Eligibility: 18 Years and older
Enrollment: 279 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: Travis Air Force Base, California • Nellis Air Force Base, Nevada

Conditions: Pain, Post Operative, Quality of Life
Interventions: Ibuprofen 600 mg, Placebo, Acetaminophen; Drug
Lead sponsor: Marquette University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Pain, Postoperative
Interventions: Caffeine Citrate, Dextrose Water; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Breast Cancer, Breast Cancer Female, Cancer of Breast
Interventions: Bupivacaine, Gabapentin, Celecoxib, Acetaminophen, Midazolam, Fentanyl; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Postoperative Pain, Opioid Use, Acetaminophen
Interventions: Rectal acetaminophen, Intravenous acetaminophen; Drug
Lead sponsor: Aultman Health Foundation; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Canton, Ohio

Conditions: Pectus Excavatum, Pain, Postoperative
Interventions: Multimodal Erector spinae catheter protocol; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 8 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Pain Management, Postoperative Pain
Interventions: Psilocybin (Usona Institute), Postoperative analgesia; Drug
Lead sponsor: Trent Emerick; Other
Eligibility: 25 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Phantom Pain
Interventions: Pregabalin, Ketamine, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Dallas, Texas

Conditions: Joint Replacement Surgery
Interventions: Dummy Movements, Psychosensory Therapy; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Postoperative Pain Management
Interventions: EXPAREL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Phantom Limb
Interventions: Cognitive Behavioral Therapy and Mirror Retraining, Supportive therapy, Mirror retraining; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 3
States / cities: Long Beach, California • San Diego, California • San Francisco, California

Conditions: Pain
Interventions: TAP catheter with Ropivicaine, Fentanyl IV PCA and placebo TAP catheter; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Post-operative Pain
Interventions: lyrica; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cerebral Palsy
Interventions: oral analgesic, intravenous analgesic per pump; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 3 Years to 17 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Pain, Postoperative, Total Knee Arthroplasty (TKA)
Interventions: Continuous Femoral Nerve Block, Nerve Block, Continuous Adductor Canal, Continuous Sciatic Nerve Block, Bupivacaine; Procedure · Drug
Lead sponsor: Kevin King, DO; Other
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Dave Bernholt; Other
Eligibility: 14 Years to 25 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 6
States / cities: Skokie, Illinois • St Louis, Missouri • Durham, North Carolina + 3 more

Conditions: Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse, Pudendal Neuralgia, Surgery
Interventions: Pudendal block; Procedure
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pelvic Organ Prolapse
Interventions: Insufflation during surgery; Procedure
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 90 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Pain, Postoperative
Interventions: fentanyl; Drug
Lead sponsor: The Medicines Company; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 10
States / cities: Palo Alto, California • Miami, Florida • Atlanta, Georgia + 7 more

Conditions: Meniscus Tear
Interventions: Reparel Sleeve, Placebo Sleeve; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 89 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Woodbury, New York

Search by objective public record fields.

Pharmacokinetic Characterization of the Active, Separated System With PK Controller (Fentanyl Iontophoretic Transdermal System, 40 Mcg Fentanyl Per Activation).

Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty

Modified TAP (Transverse Abdominis Plane) Block in Colorectal Surgery

A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief

Rapid Extremity Pain Relief by Battlefield Acupuncture After Orthopedic Surgery

Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft

Caffeine and Neurologic Recovery Following Surgery and General Anesthesia

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

Improving Post-Operative Pain and Recovery in Gynecologic Surgery

Pectus ESC Outcomes and Comparative Effectiveness Study

Psilocybin After Trauma Surgery for Pain

Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain

The Effect of a Psychosensory Therapy

Study in Adult Subjects Undergoing Posterolateral Thoracotomy

Cognitive Behavior Therapy (CBT) and Mirror Training for Phantom Limb Pain

The Effects of Continuous Transversus Abdominis Plane (TAP) Catheters on Postoperative Pain After Renal Transplantation

Postoperative Pain and Morphine Consumption After Mastectomy - Lyrica

Managing Post-operative Pain in Children With Cerebral Palsy Using a Pain Pump

Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty

Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction

Pudendal Nerve Block in Vaginal Surgery

Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial

Safety and Clinical Utility Study of SSEC Fentanyl 40 mcg for Acute Post-op Pain Management in Pediatric Participants

Novel Bioactive Sleeve on Pain and PROMs