Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:01 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Post-Operative Pain, Chronic
Interventions: Adductor Canal Block, Intra-articular Injection; Drug
Lead sponsor: Loyola University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Pediatric Post-tonsillectomy Pain
Interventions: Dexamethasone, Placebo; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 4 Years to 17 Years
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Postoperative Delirium, Postoperative Pain, Opioid Use, Hospital Length of Stay
Interventions: Gabapentin; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 65 Years and older
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2014
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Post-operative Pain Management
Interventions: Exparel, Bupivacaine; Drug
Lead sponsor: Matthew Kroh; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Postoperative Pain
Interventions: Maxigesic® IV; Drug
Lead sponsor: AFT Pharmaceuticals, Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 232 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Pasadena, Maryland • Chapel Hill, North Carolina

Conditions: Abdominal Hysterectomy (& Wertheim)
Interventions: Lidocaine, Placebo, Ketamine, Ketamine + Lidocaine; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Mayfield Heights, Ohio

Conditions: Post Operative Pain, Acute, Periodontitis
Interventions: Dexamethasone IV injection, Dexamethasone Capsule, Placebo IV administration, Placebo capsule; Drug · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions: Spinal cord stimulator; Device
Lead sponsor: Lee Fisher, PhD; Other
Eligibility: 22 Years to 70 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Postoperative Pain
Interventions: Bupivacaine, Saline Solution; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Fresno, California

Conditions: Pain, Postoperative
Interventions: Active Comparator: narcotic regimen with TAP block, Active Comparator: narcotic regimen with no TAP block, non-narcotic regimen with TAP block, non-narcotic regimen with no TAP block; Drug
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older
Enrollment: 244 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Mammoplasty, Postoperative Pain
Interventions: Instillation - EXPAREL, Infiltration - EXPAREL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Brighton, Massachusetts

Conditions: Opioid Use, Unspecified
Interventions: Methadone, Fentanyl; Drug
Lead sponsor: Andrew Waberski; Other
Eligibility: 2 Years to 7 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Spinal Surgery
Interventions: Methadone; Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Postoperative Pain
Interventions: Lidocaine, Ketamine, Saline; Drug · Other
Lead sponsor: Beth Israel Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Tonsillitis, Tonsillectomy
Interventions: Gabapentin; Drug
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 3 Years to 18 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Post Operative Pain
Interventions: Liposomal bupivacaine, 0.5% bupivacaine with 1:100,000 epinephrine; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 14 Years and older
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Chronic Pain
Interventions: Not listed
Lead sponsor: Telethon Kids Institute; Other
Eligibility: Up to 16 Years
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 7
States / cities: San Francisco, California • Aurora, Colorado • Chicago, Illinois + 4 more

Conditions: Pain, Postoperative, Amputation
Interventions: Liposomal bupivacaine, Bupivacaine Hydrochloride 0.5 % Injectable Solution; Drug
Lead sponsor: Aurora Quaye; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Portland, Maine

Conditions: Postsurgical Pain Due to Third Molar Extraction
Interventions: V117957, Ibuprofen, Placebo; Drug
Lead sponsor: Purdue Pharma LP; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Opioid-use Disorder, Pain, Postoperative
Interventions: NSS-2 Bridge, Inactive NSS-2 Bridge, Active control; Device · Other
Lead sponsor: Grace Lim, MD, MS; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Nephrectomy
Interventions: Transverses Abdominis Plane (TAP) block, Quadratus Lumborum (QL) block, Surgeon Infiltration using Exparel; Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Pain, Postoperative
Interventions: Standard dosing of methadone, Aliquots of methadone titrated to apnea; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 75 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Brain Injury, Brain Tumors, Craniotomy Surgery, Pain, Postoperative, Postoperative Care
Interventions: Remifentanil, Methadone; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Pain, Postoperative
Interventions: Transdermal Lidocaine Patch, Transdermal Hydrocolloid Placebo Patch; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 59 Years · Female only
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Search by objective public record fields.

Intra-articular Analgesia Versus Adductor Canal Block for Arthroscopic Knee Surgery

Dexamethasone and Post-tonsillectomy Pain in Children

Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain

Efficacy of Exparel (TM) on Post-operative Pain After Laparoscopic Gastric Bypass Using Circular EEA Stapler

Maxigesic® IV Phase 3 Exposure Study

Lidocaine and Ketamine in Abdominal Surgery

The Effect of Dexamethasone on Short Term Patient Response: IV vs Oral Administration

Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees, 90-Day

Peripheral Nerve Blocks for Major Lower Extremity Amputations

Pain Management Study

Study of EXPAREL in Patients Undergoing Breast Augmentation

Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery

Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for Pain Medications After Surgery

Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

Double-Blinded Randomized Controlled Study Investigating the Efficacy of Exparel (Liposomal Bupivacaine) for Postoperative Pain Relief in Mandibular Third Molar Extractions

A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations

An Analgesic Study to of V117957 for the Treatment of Postsurgical Pain Due to Third Molar Extraction

BRIDGE Percutaneous Nerve Stimulation for Cesarean Delivery Pain Control

Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy

Dosing of Methadone for Spine Surgery

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery

The OBstetric Lidocaine Patch (OBLido) Trial