Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Gynecologic Cancer, Post-operative Pain
Interventions: Bupivicaine, Placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older · Female only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Pain, Postoperative
Interventions: Liposomal bupivacaine, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Kidney Transplantation
Interventions: TAP block, liposomal bupivacaine plus free bupivacaine, normal saline; Procedure · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb Pain
Interventions: Distractor and Lower limb VR; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Fractures, Closed, Pain, Postoperative, Pain Catastrophizing, Pain, Acute, Analgesia, Opioid Use, Acceptance and Commitment Therapy, Orthopedics, Analgesics, Opioid, Text Messaging
Interventions: Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot; Behavioral
Lead sponsor: Christopher Anthony; Other
Eligibility: 18 Years to 100 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Endometriosis, Pelvic Pain
Interventions: Oral Contraceptive, Depot-Leuprolide/Norethindrone; Drug
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 52 Years · Female only
Enrollment: 194 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2004
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder, Surgery
Interventions: Ketorolac, Dexmedetomidine, Morphine, Fentanyl; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Years to 18 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Memphis, Tennessee

Conditions: Pain
Interventions: Exparel, Marcaine (Control); Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Chattanooga, Tennessee

Conditions: Pain Management
Interventions: MK-6916, Hydrocodone/acetaminophen (HB/APAP), MK-6916 Placebo, Rescue Medication; Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 380 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 9
States / cities: Miami, Florida • Tampa, Florida • Atlanta, Georgia + 6 more

Conditions: Hypospadias
Interventions: Acetaminophen, Ibuprofen, Acetaminophen, Ibuprofen, Oxycodone; Drug
Lead sponsor: University of Oklahoma; Other
Eligibility: 6 Months to 23 Months · Male only
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Pain, Postoperative
Interventions: Bridge device, Sham device; Device
Lead sponsor: Masimo Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Orthopedic Disorder
Interventions: Ropivacaine Hcl 0.5% Inj Vil 20Ml; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 2 Years to 18 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Postoperative Pain
Interventions: HTX-011, Luer Lock applicator, Vial access device, aprepitant; Drug · Device
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Age-related Macular Degeneration, Diabetic Macular Edema, Injection Site, Injection Site Infection, Pain, Postoperative
Interventions: Proparacaine, Conjunctival culture; Drug · Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Surgery
Interventions: Low Level Laser Therapy; Device
Lead sponsor: University of Toledo Health Science Campus; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Postoperative Pain, Hysterectomy
Interventions: IV Acetaminophen, IV Placebo 100 mL solution; Drug
Lead sponsor: Mallinckrodt; Industry
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 27
States / cities: Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 21 more

Conditions: Postoperative Pain
Interventions: Subpleural pain catheter with infusion of 0.125% bupivacaine, Standard acute pain management; Drug
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Falls Church, Virginia

Conditions: Arthritis - Post Surgical, Other Activity-limiting Pain
Interventions: Cognitive-Behavioral Pain Self-management Program; Behavioral
Lead sponsor: Visiting Nurse Service of New York; Other
Eligibility: 55 Years and older
Enrollment: 658 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Oral Surgery
Interventions: Vicodin, Dexamethasone; Drug
Lead sponsor: Boston University; Other
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Postoperative
Interventions: Naproxen sodium 440 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 220 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 440 mg (BAYH6689), DPH 50 mg; Drug
Lead sponsor: Bayer; Industry
Eligibility: 12 Years to 45 Years
Enrollment: 712 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: Austin, Texas • Salt Lake City, Utah

Conditions: Postoperative Pain, Opioid Use, Prolapse; Female, Incontinence
Interventions: Standard opioid prescribing, Restrictive opioid prescribing; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: ACL Surgery, Pain Management
Interventions: Meloxicam 15 mg, Medrol 4 MG Oral Tablet Includes Medrol Dosepak, Gabapentin 300 mg, Hydrocodone 5Mg/Acetaminophen 325Mg Tab, Ketorolac 10 Mg Oral Tablet; Drug
Lead sponsor: St. Louis University; Other
Eligibility: 13 Years to 50 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pain, Postoperative
Interventions: continuous erector spinae block (ESB), continuous paravertebral block (PVB), Ropivacaine; Procedure · Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 1 Month to 12 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Post Operative Pain
Interventions: Lidocaine Hydrochloride, Placebo; Drug · Other
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Roanoke, Virginia

Search by objective public record fields.

Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery

Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain

Does an Abdominal Wall Nerve Block During Surgery Help Reduce Pain From Kidney Transplantation?

Virtual Reality Treatment for Phantom Limb Pain

Pain and Narcotic Usage After Orthopaedic Surgery

Medical Treatment of Endometriosis-Associated Pelvic Pain

Opioid-Free Anesthetic for Tonsillectomy

Early Post-Operative Pain Control Following Wrist Operations

A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007)

Assessment of Postop Hypospadias Pain

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

Comparative Evaluation of Lumbar Plexus and Suprainguinal Fascia Iliaca Compartment Blocks

Phase 2 Bunionectomy HTX-011 Administration Study

Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections

Assessment of Low Level Laser Therapy for Late Postoperative Pain After Lumbar Fusion Surgery

Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery

Continuous Subpleural Infusion of Bupivacaine

Treating Pain to Reduce Disability Among Older Home Health Patients

Pilot Study: Effect of Dexamethasone vs Vicodin in Reducing Post-operative Pain

Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain

STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial

Efficacy of Methylprednisolone for Pain Control After ACL Repair

Continuous Erector Spinae Block Versus Continuous Paravertebral Block

Systemic Lidocaine Infusion for Pain Control in Ventral Hernia