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ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:55 PM EDT

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Showing 481–504 of 2,226 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Traumatic Clear all
Suspended Phase 2 Interventional Accepts healthy volunteers

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

NCT05422612
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Intervention A Fluoxetine Hydrochloride (HCl), Intervention A Placebo, Intervention B Vilazodone Hydrochloride (HCl), Intervention B Placebo, Intervention C Daridorexant, Intervention C Placebo, Intervention D SLS-002, Intervention D Placebo
Drug
Lead sponsor
Global Coalition for Adaptive Research
Other
Eligibility
18 Years to 65 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
9
States / cities
Miami, Florida • Atlanta, Georgia • Tripler AMC, Hawaii + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Early Phase 1 Interventional

Yoga Based Psychotherapy Group Feasibility and Efficacy Study

NCT01524172
View directory record Official record
Conditions
Emotional Lability, PTSD
Interventions
Yoga Based Psychotherapy Group, Standard Mental Health Treatment
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
8 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Oct 24, 2026, 2:55 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD: Neurokinetics, Inc, iPAS

NCT03465995
View directory record Official record
Conditions
Traumatic Brain Injury, Post Traumatic Stress Disorder
Interventions
NKI i-PAS Diagnostic Protocol
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FOCUS:Families OverComing Under Stress

NCT02992405
View directory record Official record
Conditions
Cancer, Depression, PostTraumatic Stress Disorder, Anxiety
Interventions
FOCUS Resilience Enhancement Program, Waitlist (No Study Treatment)
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
5 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)

NCT05144477
View directory record Official record
Conditions
Cardiac Arrest, Post Traumatic Stress Syndrome
Interventions
FAID Fear Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2023 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress

NCT04329702
View directory record Official record
Conditions
Cardiorespiratory Failure
Interventions
Coping skills training mobile app with call from CST therapist, Coping skills training mobile app only
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 24, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional

Promoting Improved Functioning Among People Experiencing Stressful Situations

NCT06482567
View directory record Official record
Conditions
Acute Stress Reaction
Interventions
iCOVER, Physical Presence with Reassurance
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Belmont, Massachusetts • Worcester, Massachusetts • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Functional Outcomes of Cannabis Use (FOCUS) in Veterans With Posttraumatic Stress Disorder

NCT04565028
View directory record Official record
Conditions
PTSD, Cannabis-Related Disorder
Interventions
Contingency Management (CM)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 24, 2026, 2:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

ICU Experience in Family Members

NCT02940028
View directory record Official record
Conditions
Post-Traumatic Growth, Psychological
Interventions
Expressive writing, Control writing
Behavioral
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 24, 2026, 2:55 PM EDT
Withdrawn Phase 4 Interventional

Effects of Paliperidone in Posttraumatic Stress Disorder (PTSD)

NCT00766064
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Paliperidone
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 23, 2016 · Synced Oct 24, 2026, 2:55 PM EDT
Not listed Not applicable Interventional

NightWare Open Enrollment Study

NCT03828656
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders, Combat Disorders, Nightmares Associated With Chronic Post-Traumatic Stress Disorder, Nightmare, Nightmares, REM-Sleep Type
Interventions
NightWare Therapeutic System
Device
Lead sponsor
NightWare
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Cognitive Processing Therapy Versus Prolonged Exposure for Treating Women With Post-Traumatic Stress Disorder Brought on by Sexual Assault

NCT00239772
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy, Prolonged Exposure Therapy
Behavioral
Lead sponsor
University of Missouri, St. Louis
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1994
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 5, 2014 · Synced Oct 24, 2026, 2:55 PM EDT
Terminated Not applicable Interventional Results available

Imaginal Exposure & D-Cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)

NCT00875342
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
DCS, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

DDBT Adapted Problem Solving Treatment for Primary Care

NCT03514394
View directory record Official record
Conditions
Depression, PTSD
Interventions
Usual Care, Modified Behavioral Activation (Task Sharing)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Hardin, Montana
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Studying the Modification of Attention Bias Remotely After Trauma

NCT04888169
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
SMART Mobile App - Attention Bias Modification, SMART Mobile App - Attention Control Training, SMART Mobile App - Placebo Training, SMART Mobile App - Control
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
1,314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Remotely Supervised tDCS for Persistent Post-traumatic Headache

NCT04012853
View directory record Official record
Conditions
Persistent Post Traumatic Headache, Mild Traumatic Brain Injury
Interventions
transcranial direct current stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Mindfulness for Alcohol Use and PTSD Among Veterans

NCT04769986
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder
Interventions
Mobile Mindfulness-Relapse Prevention (mMBRP), Exercise/healthy eating mobile app
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Menlo Park, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Phase 2 Interventional Results available

Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder

NCT00383786
View directory record Official record
Conditions
PTSD
Interventions
NK1 Antagoist (GR205171), Psychophysiology (Trauma Script), Psychophysiology (Verbal Threat), Psychophysiology (Fear Conditioning), Psychophysiology (Affective Modulation), Psychophysiology (Heart rate variability), Lumbar Puncture, 24-hour plasma sampling, MRI
Drug · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Bethesda, Maryland • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 24, 2026, 2:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Network Study: Soldiers Connecting for Work and Health

NCT04463225
View directory record Official record
Conditions
Alcohol Use Disorder, Depression
Interventions
Internet-Delivered Brief Intervention
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 62 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Outcomes After Spinal Cord Injury (OASIS)

NCT03624218
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Spinal Cord Injuries
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD

NCT01990079
View directory record Official record
Conditions
PTSD, Smoking
Interventions
Bupropion, nicotine replacement therapy, Smoking cessation counseling, mobile contingency management, Stay Quit Coach
Drug · Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 24, 2026, 2:55 PM EDT
Not yet recruiting Not applicable Interventional

Self-Compassion, Health, and Empowerment

NCT07733531
View directory record Official record
Conditions
Intimate Partner Violence (IPV), Depression and/or Anxiety Symptoms, PTSD - Post Traumatic Stress Disorder
Interventions
The Self-Compassion, Health, and Empowerment (SHE) Intervention, Health and Nutrition Program
Behavioral
Lead sponsor
Yang Li
Other
Eligibility
18 Years and older · Female only
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 24, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional

Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

NCT07176273
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment, Digital Interventions, Cognitive Processing Therapy (CPT), Prolonged Exposure (PE)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Augusta, Georgia • Ann Arbor, Michigan • Battle Creek, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 24, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Effectiveness of Sana Treatment in Post-Traumatic Stress Disorder (PTSD)

NCT05319405
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Sana Device
Device
Lead sponsor
Sana Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 24, 2026, 2:55 PM EDT