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ClinicalTrials.gov public records Last synced Oct 25, 2026, 12:52 AM EDT

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Showing 529–552 of 2,226 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Traumatic Clear all
Completed Not applicable Interventional

Cognitive Remediation in Posttraumatic Stress Disorder (PTSD)

NCT00850447
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Remediation Therapy, Videogame
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2012 · Synced Oct 25, 2026, 12:52 AM EDT
Recruiting Phase 2 Interventional

Dose Optimization of MDMA-Assisted Therapy for PTSD

NCT06418178
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Midomafetamine, Psychotherapy
Drug · Behavioral
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional

Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder: A Pilot Study

NCT00880152
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression
Interventions
Mindfulness-based stress reduction
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 24, 2010 · Synced Oct 25, 2026, 12:52 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Nerve Stimulation for PTSD and Sleep

NCT03170440
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcutaneous nerve stimulation location 1
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 55 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Phase 2Phase 3 Interventional Results available

CPT and Smoking Cessation

NCT01901848
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Smoking
Interventions
Cognitive Processing Therapy (CPT), Bupropion, nicotine replacement therapy (NRT), Integrated Care for Smoking Cessation (ICSC), smokefreeVET
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 25, 2026, 12:52 AM EDT
Recruiting Not applicable Interventional

Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD

NCT07069517
View directory record Official record
Conditions
Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET), Sleep Hygiene
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Kileen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 25, 2026, 12:52 AM EDT
Recruiting Phase 2 Interventional

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

NCT06902974
View directory record Official record
Conditions
Post Traumatic Stress Disorder, PTSD
Interventions
Psilocybin 25 mg
Drug
Lead sponsor
Sunstone Medical
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors

NCT06571513
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Written Exposure Therapy, Unemotional Writing
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional Results available

Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States

NCT04163341
View directory record Official record
Conditions
HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder, Substance Use Disorders
Interventions
Adapted Common Elements Treatment Approach
Behavioral
Lead sponsor
Michael J Mugavero, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional Results available

Reducing Alcohol Use & Post-traumatic Stress Disorder (PTSD) With Cognitive Restructuring & Experiential Acceptance

NCT00760994
View directory record Official record
Conditions
Alcoholism, Stress Disorders, Post-Traumatic
Interventions
Experiential acceptance, Cognitive restructuring, No-intervention control: Nutrition information
Behavioral · Other
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional

Optimal Dose of Early Intervention to Prevent PTSD

NCT01959620
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
1-Session Exposure Therapy, 3-Session Exposure Therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 25, 2026, 12:52 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NightWare and Cardiovascular Health in Veterans With PTSD

NCT06419959
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction, Veteran
Interventions
NightWare
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 88 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans

NCT00625105
View directory record Official record
Conditions
PTSD
Interventions
Biofeedback
Behavioral
Lead sponsor
William Jennings Bryan Dorn VA Medical Center
Federal
Eligibility
20 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2014 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Phase 1Phase 2 Interventional

Group MDMA-therapy for Veterans With PTSD

NCT05961527
View directory record Official record
Conditions
PTSD
Interventions
MDMA, Group Therapy
Drug · Behavioral
Lead sponsor
Portland VA Research Foundation, Inc
Other
Eligibility
18 Years to 64 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 25, 2026, 12:52 AM EDT
Withdrawn Phase 4 Interventional

Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD)

NCT00706173
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Hydrocortisone, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 25, 2026, 12:52 AM EDT
Recruiting Not applicable Interventional

Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

NCT05751473
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
14
States / cities
San Diego, California • Carrollton, Georgia • Ann Arbor, Michigan + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional

Innovative Service Delivery for Secondary Prevention of PTSD

NCT01177488
View directory record Official record
Conditions
PTSD
Interventions
Behavioral Activation Therapeutic Exposure (BATE)
Behavioral
Lead sponsor
Charleston Research Institute
Other
Eligibility
21 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2015 · Synced Oct 25, 2026, 12:52 AM EDT
Not yet recruiting Phase 1 Interventional

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

NCT07004764
View directory record Official record
Conditions
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Calcaneus Fractures, Talus Fracture, Wound Infection Deep, Wound Infection Post-Traumatic, Wound Dehiscence, Surgical
Interventions
Nitroglycerin Ointment 2%
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional

tAN for PTSD and OUD in Buprenorphine Therapy

NCT06130501
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Opioid Use Disorder
Interventions
Sparrow Ascent tAN, Sparrow Ascent Active Sham
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cape Girardeau, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Theta-Burst Neuromodulation for PTSD

NCT02769312
View directory record Official record
Conditions
Chronic Post-Traumatic Stress Disorder
Interventions
Theta burst stimulation, Sham stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using mHealth to Improve Emotional Recovery After Pediatric Injury

NCT04579198
View directory record Official record
Conditions
Trauma Injury, Child, Only, Posttraumatic Stress Disorder, Parents
Interventions
Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 25, 2026, 12:52 AM EDT
Completed Not applicable Interventional Results available

A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)

NCT00984698
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Insomnia Disorder
Interventions
Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Oct 25, 2026, 12:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Experiential Avoidance in Combat Veterans With and Without Posttraumatic Stress Disorder

NCT01652430
View directory record Official record
Conditions
PTSD, Suicidal Ideation
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 65 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Oct 25, 2026, 12:52 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted Psychotherapy

NCT05274230
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Apollo Wearable
Device
Lead sponsor
Apollo Neuroscience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Oct 25, 2026, 12:52 AM EDT