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ClinicalTrials.gov public records Last synced Oct 30, 2026, 8:16 AM EDT

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Showing 817–840 of 2,231 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Traumatic Clear all
Completed No phase listed Observational Accepts healthy volunteers

Deployment Related Mild Traumatic Brain Injury (mTBI)

NCT01847040
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
The Defense and Veterans Brain Injury Center
Federal
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Fort Carson, Colorado • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Oct 30, 2026, 8:16 AM EDT
Recruiting Phase 1 Interventional

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

NCT05915013
View directory record Official record
Conditions
Depressive Disorder, Major, Post Traumatic Stress Disorder
Interventions
Ketamine, Perampanel, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain

NCT05254379
View directory record Official record
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD), Depression
Interventions
tDCS
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional

CONcussion Treatment After Combat Trauma (CONTACT)

NCT01387490
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Individualized Scheduled Telephone Support (ISTS), Usual Care (UC)
Behavioral · Other
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years and older
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Durham, North Carolina • Fort Bragg, North Carolina • Fort Lewis, Washington + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2016 · Synced Oct 30, 2026, 8:16 AM EDT
Terminated Not applicable Interventional Results available

Orthosis of Acute Traumatic Rib Fractures Via RibFx Belt for Pain Alleviation and Improved Pulmonary Function

NCT03846024
View directory record Official record
Conditions
Rib Fracture, Rib Fracture Multiple, Trauma, Trauma Chest, Trauma Injury, Trauma, Multiple
Interventions
RibFx Orthosis Belt
Device
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Oct 30, 2026, 8:16 AM EDT
Not yet recruiting Not applicable Interventional

First Responder Safety Training (FiRST)

NCT07478250
View directory record Official record
Conditions
Resilience and Mental Health of First Responders
Interventions
Worker Resilience Training Program, Fire and Medical Safety (FAMS)
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Stony Brook, New York • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Withdrawn Early Phase 1 Interventional

Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD)

NCT04966546
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Memantine Hydrochloride, Placebo
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Phase 4 Interventional Results available

Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments

NCT01490697
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Mifepristone, d-Cycloserine, Placebo-matching Mifepristone, Placebo-matching d-Cycloserine (DCS)
Drug
Lead sponsor
Roger K. Pitman, MD
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2017 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional Results available

Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder

NCT00539279
View directory record Official record
Conditions
Combat Disorders, Post-traumatic Stress Disorder
Interventions
Prolonged Exposure Therapy (PE), Relaxation Training (RT)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older · Male only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Phase 4 Interventional Results available

Dopamine Enhancement of Fear Extinction Learning in PTSD (1R21MH108753)

NCT02560389
View directory record Official record
Conditions
Stress Disorder, Post Traumatic
Interventions
Placebo, Levodopa
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
25 Years to 50 Years · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 30, 2026, 8:16 AM EDT
Terminated No phase listed Observational

Hyperbaric Oxygen Therapy in Chronic Traumatic Brain Injury or Post-Traumatic Stress Disorder

NCT01105962
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
International Hyperbaric Medical Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
10
States / cities
San Francisco, California • Boulder, Colorado • Delray Beach, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Oct 30, 2026, 8:16 AM EDT
Recruiting Not applicable Interventional

A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD

NCT06990191
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Partnered Prolonged Exposure (PPE), Prolonged Exposure (PE)
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • San Diego, California • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Withdrawn Phase 4 Interventional

Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD)

NCT00706173
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Hydrocortisone, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 30, 2026, 8:16 AM EDT
Active, not recruiting Not applicable Interventional

An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers

NCT06054412
View directory record Official record
Conditions
Well-Being, Psychological, Dissociation, Maternal Care Patterns, Maternal Behavior, Maternal Distress, Mood Disturbance, Emotional Regulation, Post Traumatic Stress Disorder
Interventions
Neuroptimal (Zengar, Inc.) Neurofeedback
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Phase 3 Interventional

Multicenter Evaluation of Memory Remediation After TBI With Donepezil

NCT02255799
View directory record Official record
Conditions
Traumatic Brain Injury, Memory Deficits
Interventions
Donepezil, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
4
States / cities
Indianapolis, Indiana • Charlestown, Massachusetts • Elkins Park, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 30, 2026, 8:16 AM EDT
Recruiting Not applicable Interventional

University of Colorado - Restoring Efficient Sleep After TBI

NCT05683145
View directory record Official record
Conditions
Insomnia, Traumatic Brain Injury
Interventions
Computerized Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Terminated Not applicable Interventional Results available

Ascension® Post- Approval Study; PyroCarbon Metacarpophalangeal Total Joint Prosthesis

NCT02408471
View directory record Official record
Conditions
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Post-traumatic Arthritis
Interventions
Ascension® MCP Finger Implant
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
9
States / cities
Tucson, Arizona • Bloomington, Indiana • Carmel, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 30, 2026, 8:16 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Neuroeconomics of Social Behavior Following Trauma Exposure

NCT03383536
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Therapeutic Learning Among Women With PTSD

NCT04113798
View directory record Official record
Conditions
PTSD
Interventions
Day 1 Assessments, Day 2 Fear Learning, Day 3 Fear Extinction, Moderate Intensity Exercise, Low Intensity Exercise, Day 4 Recall of Fear Extinction
Other · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 19, 2020 · Synced Oct 30, 2026, 8:16 AM EDT
Completed No phase listed Observational

Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

NCT03947099
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety Disorders
Interventions
Ketamine Hydrochloride
Drug
Lead sponsor
Klarisana Physician Services PLLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional Results available

Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women

NCT04605198
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depressive Symptoms, Hydrocortisone, Substance Use
Interventions
Modified Mindfulness-based Stress Reduction, Health Promotion Wellness Classes
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Escondido, California • Pomona, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional Results available

Trauma Survivors Outcomes and Support Study IV

NCT01625416
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions
Stepped Care Management
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Oct 30, 2026, 8:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Grappling With Trauma: Brazilian Jiu-Jitsu for First Responders

NCT07783516
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Trauma and Stress Related Disorders, Occupational Stress, Emotional Regulation Difficulties, Anger Problems, Relational Problems, Irritability
Interventions
Brazilian Jiu-Jitsu Program
Behavioral
Lead sponsor
Sam Houston State University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Conroe, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 30, 2026, 8:16 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality & D-cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)

NCT00632632
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
D-Cycloserine, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2015 · Synced Oct 30, 2026, 8:16 AM EDT