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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:12 PM EDT

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Showing 145–168 of 2,225 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Traumatic Clear all
Recruiting Phase 2 Interventional

Focused Ultrasound for PTSD in Veterans

NCT06820138
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Brainsonix Ultrasound Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 22, 2026, 2:12 PM EDT
Active, not recruiting No phase listed Observational

The BEAR Therapeutic Program for Women

NCT04418778
View directory record Official record
Conditions
Trauma, Psychological, Depression, Anxiety, PTSD
Interventions
BEAR
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 22, 2026, 2:12 PM EDT
Active, not recruiting Not applicable Interventional

Brain Stimulation for Concussion

NCT05889117
View directory record Official record
Conditions
Transcranial Magnetic Stimulation, Magnetic Resonance Imaging, Neuropsychological Tests, Traumatic Brain Injury, Post-Concussion Syndrome
Interventions
Intermittent theta-burst treatment (iTBS) using MagPro Transcranial Magnetic Stimulator (manufacturer: Magventure)
Device
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 22, 2026, 2:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Psychedelics and Wellness Study (PAWS)

NCT04040582
View directory record Official record
Conditions
Depression, Anxiety, PTSD
Interventions
Not listed
Lead sponsor
WILD 5 Wellness
Other
Eligibility
18 Years to 100 Years
Enrollment
3,234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Oct 22, 2026, 2:12 PM EDT
Terminated No phase listed Observational

Clinical Evaluation of the TITAN™ Total Shoulder System

NCT03245320
View directory record Official record
Conditions
Arthritis, Arthritis, Degenerative, Rheumatoid Arthritis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Syndrome of Shoulder and Allied Disorders, Fracture, Avascular Necrosis, Joint Instability, Joint Trauma, Dislocation, Shoulder, Pain, Shoulder
Interventions
Integra TITAN™ Total Shoulder Generation 1.0
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Indianapolis, Indiana • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 22, 2026, 2:12 PM EDT
Withdrawn Phase 1 Interventional

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

NCT03752918
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
MDMA, Niacin
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 22, 2026, 2:12 PM EDT
Not listed No phase listed Observational

Effect of Different Intravenous Fluids on Post-operative Chronic Subdural Hematoma Size and Recurrence

NCT03831997
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Dextrose 5% W/ Sodium Chloride 0.225%
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 22, 2026, 2:12 PM EDT
Withdrawn Not applicable Interventional

Post-traumatic Occipital Neuralgia - Surgical Versus Medical Management

NCT03253523
View directory record Official record
Conditions
Post-Traumatic Neuralgia, Occipital Neuralgia
Interventions
Occipital neurolysis
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Intervention for Veterans With Depression, Substance Disorder, and Trauma

NCT00958217
View directory record Official record
Conditions
Depressive Symptoms, Substance-related Disorders, Posttraumatic Stress Disorders
Interventions
Cognitive Processing Therapy-Modified (CPT-M), Integrated Cognitive Behavioral Therapy (ICBT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Outcomes After Spinal Cord Injury (OASIS)

NCT03624218
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Spinal Cord Injuries
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

A Self-Management Program for Completers of Trauma-Focused Therapy for PTSD

NCT03225859
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Self-Management Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 22, 2026, 2:12 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain Injury

NCT01260090
View directory record Official record
Conditions
Minimally Conscious States Due to Traumatic Brain Injury, Persistently Vegetative States Due to Traumatic Brain Injury
Interventions
Vagus nerve stimulation;, No stimulation
Device
Lead sponsor
VA New York Harbor Healthcare System
Federal
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance

NCT03216980
View directory record Official record
Conditions
Mental Health Disorders
Interventions
PTSD/GAD Antioxidant, PTSD/GAD Placebo, Healthy Control Antioxidant, Healthy Control Placebo
Dietary Supplement
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 22, 2026, 2:12 PM EDT
Enrolling by invitation No phase listed Observational

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

NCT06823024
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD, Generalized Anxiety Disorder (GAD)
Interventions
Not listed
Lead sponsor
Psyrin Inc.
Industry
Eligibility
18 Years to 68 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Sunnyvale, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Behavioral Activation for Smoking Cessation in PTSD

NCT01995123
View directory record Official record
Conditions
Tobacco Dependence, PTSD
Interventions
Behavioral Activation Therapy, Health and Smoking Education, Standard Smoking Cessation Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Brain Injury Rehabilitation Improving the Transition Experience

NCT03422276
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Rehabilitation Discharge Plan, Rehabilitation Transition Plan
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,555 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
6
States / cities
Indianapolis, Indiana • New York, New York • Columbus, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy to Improve Work and Wellness in Veterans With Mental Illness

NCT04504903
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Cognitive Behavioral Therapy For Work Success (CBTw), Psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Hines, Illinois • Indianapolis, Indiana • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder

NCT00868517
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
Interventions
True group auricular acupuncture, Sham group auricular acupuncture, Wait-List Control Group
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Self-Advocacy for Independent Life (SAIL) After TBI

NCT03385824
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Self-Advocacy for Independent Life (SAIL)
Behavioral
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Phase 1Phase 2 Interventional

Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy

NCT00121888
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure Therapy, Paroxetine-CR
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 72 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 6, 2014 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)

NCT03874793
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Mindfulness-Based Cognitive Therapy, Muscle Relaxation Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 72 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Ann Arbor, Michigan • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Trauma Management Therapy for OEF and OIF Combat Veterans

NCT02809326
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Combat Disorders
Interventions
17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Oct 22, 2026, 2:12 PM EDT
Not listed Phase 1Phase 2 Interventional

Web-based CBT for Recent Veterans Experiencing Problems With Trauma Symptoms or Alcohol/Drug Use

NCT01710943
View directory record Official record
Conditions
Post-Traumatic Stress Symptoms, Problematic Use of Alcohol or Other Drugs
Interventions
Web-based Cognitive Behavioral Treatment
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Buffalo, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2012 · Synced Oct 22, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Neurohormonal Benefits of Exercise in Fibromyalgia and PTSD

NCT03236467
View directory record Official record
Conditions
FM and PTSD
Interventions
Progressive Exercise Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Oct 22, 2026, 2:12 PM EDT