- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Other Inflammatory Arthritis, Post-Traumatic Arthritis, Juvenile Rheumatoid Arthritis, Avascular Necrosis
- Interventions
- Total Knee Arthroplasty, Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 149 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 3
- States / cities
- Greensboro, North Carolina • Austin, Texas • Lakewood, Washington
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Showing 1–24
of 42
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Knee Osteoarthritis
- Interventions
- Whole body vibration, Local muscle vibration
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Knee Osteoarthristis, ACL Injuries, Post-Traumatic
- Interventions
- extracorporeal shockwave therapy (ESWT), Sham Comparator
- Device
- Lead sponsor
- Spaulding Rehabilitation Hospital
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
- Interventions
- Zimmer Biomet Persona Ti-Nidium Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2034
- U.S. locations
- 7
- States / cities
- Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
- Conditions
- Post-traumatic Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- James Stannard
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Juvenile Rheumatoid Arthritis, Avascular Necrosis of Bone
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 2
- States / cities
- Billings, Montana • Vancouver, Washington
- Conditions
- Knee Osteoarthritis, Post-traumatic Osteoarthritis
- Interventions
- Unicompartmental Biologic Arthroplasty, Extensive Biologic Arthroplasty
- Procedure
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Arthritis
- Interventions
- Not listed
- Lead sponsor
- Orthosensor, Inc.
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 285 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 8
- States / cities
- St. Helena, California • Fort Lauderdale, Florida • Naples, Florida + 5 more
- Conditions
- Total Knee Arthroplasty
- Interventions
- Journey II BCS Total Knee System
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 1,694 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 9
- States / cities
- Aurora, Colorado • Gulf Breeze, Florida • Indianapolis, Indiana + 6 more
- Conditions
- Post-traumatic Osteoarthritis of the Knee
- Interventions
- FX006 32 mg, TCA IR 40 mg
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 20 Years to 50 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total Knee Arthroplasty
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 299 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2033
- U.S. locations
- 12
- States / cities
- Atlanta, Georgia • Boston, Massachusetts • Novi, Michigan + 8 more
- Conditions
- Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
- Interventions
- Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction
- Biological · Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • New York, New York
- Conditions
- Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis, Degenerative Arthritis Peripheral Joint, Failed Osteotomies, Failed Unicompartmental Replacement
- Interventions
- JOURNEY II XR Total Knee System
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 176 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2029
- U.S. locations
- 14
- States / cities
- Loma Linda, California • Fort Lauderdale, Florida • Aurora, Illinois + 9 more
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Juvenile Arthritis
- Interventions
- Total knee arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 210 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 3
- States / cities
- Denver, Colorado • Pittsburgh, Pennsylvania • Virginia Beach, Virginia
- Conditions
- Osteoarthritis, Post-traumatic Arthritis
- Interventions
- ATTUNE TKA with ATTUNE RUI, ATTUNE TKA with ATTUNE SUI
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 2
- States / cities
- La Jolla, California • Wilkes-Barre, Pennsylvania
- Conditions
- Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity, Knee Pain Chronic
- Interventions
- Persona Partial Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2030
- U.S. locations
- 1
- States / cities
- Jackson, Mississippi
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Interventions
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Device · Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Non-inflammatory Degenerative Joint Disease
- Interventions
- Journey UNI Unicompartmental Knee System
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 3
- States / cities
- Scottsdale, Arizona • Park Ridge, Illinois • Nashville, Tennessee
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
- Interventions
- platelet rich plasma (PRP) injection, placebo saline injection
- Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 14 Years to 50 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis), Post-traumatic Arthritis
- Interventions
- Cemented CoCr, Cemented Oxinium, Cementless
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2036
- U.S. locations
- 4
- States / cities
- Newton, Massachusetts • New York, New York • Charleston, South Carolina + 1 more
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon PKR
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2023
- U.S. locations
- 6
- States / cities
- Jacksonville, Florida • Egg Harbor, New Jersey • Buffalo, New York + 3 more
- Conditions
- Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
- Interventions
- Physica Kinematic Retaining Knee System, Physica Cruciate Retaining Knee System, Physica Posterior Stabilized Knee System, Physica Cruciate Retaining Knee System with LMC Liner
- Device
- Lead sponsor
- Limacorporate S.p.a
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 800 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2030
- U.S. locations
- 5
- States / cities
- Rancho Mirage, California • Daytona Beach, Florida • Aurora, Illinois + 2 more
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Avascular Necrosis of Bone, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 399 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 4
- States / cities
- La Jolla, California • Crystal River, Florida • Melbourne, Florida + 1 more
- Conditions
- Post-traumatic Osteoarthritis, Knee Sprain, Knee Injuries
- Interventions
- mCare PTOA Intervention
- Behavioral
- Lead sponsor
- Keller Army Community Hospital
- Federal
- Eligibility
- 18 Years to 54 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- West Point, New York