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ClinicalTrials.gov public records Last synced Oct 10, 2026, 6:06 PM EDT

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Showing 169–192 of 1,622 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-Traumatic Stress Disorder (PTSD) Clear all
Withdrawn Phase 1 Interventional

Dexamethasone as an Immediate Intervention

NCT02753166
View directory record Official record
Conditions
Trauma
Interventions
Dexamethasone
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Oct 10, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The PREVENT Resilience Study

NCT07568145
View directory record Official record
Conditions
Psychological Trauma
Interventions
Transcranial Magnetic Stimulation (TMS), TMS Sham
Device · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Early Phase 1 Interventional

Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury

NCT04280965
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Quetiapine Fumarate, Standard of care meducations
Drug · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

Expressing Personal Recollections in English or Spanish to Alleviate Traumatic Emotions (Exprésate)

NCT05090839
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Weekly Emotional Disclosure (WED), Weekly Emotional Disclosure (WED) Spanish
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
21 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Phase 4 Interventional Results available

Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)

NCT01517711
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Tramadol, Placebo
Drug
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

NCT02657317
View directory record Official record
Conditions
Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions
FORT-A, VA Treatment as Usual
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 72 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals

NCT05520190
View directory record Official record
Conditions
Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety, Insomnia, Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Stress, Sleep and Cardiovascular Risk

NCT03487991
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia
Interventions
Personalized sleep intervention
Behavioral
Lead sponsor
Howard University
Other
Eligibility
18 Years to 35 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Oct 10, 2026, 6:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families

NCT06548126
View directory record Official record
Conditions
Child Safety, Coercion, Child Wellbeing, Adjustment, Parenting, Post Traumatic Stress Disorder, Mental Health, Child Maltreatment, Trauma, Emotional Regulation
Interventions
Online Parenting Program, No online parenting program
Behavioral · Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 10, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional

Biomarkers in the Retina for Prognosticating Mental Health Treatments

NCT06363968
View directory record Official record
Conditions
PTSD, Posttraumatic Stress Disorder
Interventions
RETeval
Device
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
21 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 10, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans

NCT05995678
View directory record Official record
Conditions
TBI, Suicide Prevention, Veterans, PTSD, Transdiagnostic, Anger
Interventions
STEP-Home-SP, Transition Assistance Program, VA Solid Start
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 10, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional

Using Exercise to Enhance Fear Extinction Learning

NCT07548125
View directory record Official record
Conditions
PTSD, Exercise Intensity, Fear Extinction, Fear Conditioning
Interventions
Exercise
Behavioral
Lead sponsor
Josh Cisler
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac Events

NCT06048068
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Educational Informational Platform
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

Neurofeedback Impact on Veterans With mTBI

NCT04195685
View directory record Official record
Conditions
Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache, Chronic Insomnia, Chronic Attention Disorder
Interventions
Neurofeedback (NFB)
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Not yet recruiting Not applicable Interventional

First Responder Safety Training (FiRST)

NCT07478250
View directory record Official record
Conditions
Resilience and Mental Health of First Responders
Interventions
Worker Resilience Training Program, Fire and Medical Safety (FAMS)
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Stony Brook, New York • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional

Cognitive Processing Therapy Versus Its Individual Components in the Treatment of Post-Traumatic Stress Disorder and Depression in Women Who Have Been Sexually Abused

NCT00245232
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Therapy, Cognitive Processing Therapy, Written Exposure
Behavioral
Lead sponsor
University of Missouri, St. Louis
Other
Eligibility
18 Years and older · Female only
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Attention Bias Modification Treatment for Warzone-Related Posttraumatic Stress Disorder (PTSD)

NCT01564667
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Attention Bias Modification Training Protocol
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RRT for PTSD Symptoms in Survivors of Sexual Violence

NCT04073004
View directory record Official record
Conditions
PTSD, Rape Sexual Assault
Interventions
Rapid Resolution Therapy
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Neurosensory Account of Anxiety and Stress (Study 1)

NCT05895006
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Intrinsic and Novelty-related Sensory Cortical (SC) Disinhibition
Interventions
Alternating Current Stimulation (tACS), Sham for Transcranial Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional

taVNS to Reduce PTSD Symptoms in WTC Responders

NCT05212714
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
taVNS
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)

NCT00984698
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Insomnia Disorder
Interventions
Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Oct 10, 2026, 6:06 PM EDT
Terminated Phase 2 Interventional

Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD

NCT02733614
View directory record Official record
Conditions
PTSD
Interventions
SRX246, Placebo
Drug
Lead sponsor
Azevan Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 10, 2026, 6:06 PM EDT
Completed Phase 2 Interventional

Acceptability and Feasibility of Apollo in Veterans With a History of PTSD

NCT05019651
View directory record Official record
Conditions
PTSD
Interventions
Apollo Wearable System
Device
Lead sponsor
Lisa Brenner
Federal
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Oct 10, 2026, 6:06 PM EDT
Not listed Phase 1Phase 2 Interventional

Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2

NCT04846010
View directory record Official record
Conditions
Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder), Post-Infectious Arthritis, Post-Infectious Polyneuritis, Post-Infectious Parkinsonism, Post-Infectious Hypothyroidism, Post Infectious Osteoarthritis, Anxiety Disorders, Depression, Depression, Anxiety, Depression, Bipolar, Insomnia, GERD, Gastro Esophageal Reflux, Hepatitis, Glomerulonephritis
Interventions
PurWet, FurFat, PurApo, PurPhl, PurClo, PurInf, Smoliv
Combination Product
Lead sponsor
All Natural Medicine Clinic, LLC
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Oct 10, 2026, 6:06 PM EDT