- Conditions
- Post Concussion Syndrome
- Interventions
- Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy
- Device · Other
- Lead sponsor
- Neuroscience Group
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Appleton, Wisconsin
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Showing 25–48
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- Conditions
- Concussion (Diagnosis), Concussion Post Syndrome, Concussion, Mild
- Interventions
- Brain Cooling
- Device
- Lead sponsor
- Penn State University
- Other
- Eligibility
- 18 Years to 27 Years · Female only
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- University Park, Pennsylvania
- Conditions
- Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury, Headache, Dizziness, Cognitive Symptom, Dysautonomia, Anxiety, Irritability; Syndrome, Depression, Post-traumatic Stress Disorder
- Interventions
- Active cTBS, Inactive/Sham cTBS, Imaginal exposure
- Device · Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Westwood, Los Angeles, California
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury
- Interventions
- electronic Clinical Decision Support tool for risk stratification of pediatric patients with mTBI
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 5 Years to 18 Years
- Enrollment
- 3,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Mild Traumatic Brain Injury, Concussion, Post-concussive Syndrome
- Interventions
- Mandated Rest, Intervention
- Behavioral
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 11 Years to 22 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Cerebral Concussion, Brain Injuries
- Interventions
- Not listed
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 437 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Post-Concussion Symptoms, Distorted; Balance
- Interventions
- Osteopathic Manipulative Treatment, Counseling
- Procedure · Other
- Lead sponsor
- New York Institute of Technology
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2023
- U.S. locations
- 1
- States / cities
- Old Westbury, New York
- Conditions
- Traumatic Brain Injury, PTSD, Depression
- Interventions
- Not listed
- Lead sponsor
- National Institute of Nursing Research (NINR)
- NIH
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Vascular System Injuries, Concussion, Brain, Post-Concussion Syndrome
- Interventions
- Sildenafil Citrate, Placebo oral capsule
- Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years to 35 Years · Male only
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Persistent Post-concussive Symptoms, Post Traumatic Headache
- Interventions
- SPINEPASS Physical Therapy, Standard Physical Therapy
- Other
- Lead sponsor
- The University of Queensland
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Traumatic Brain Injury, Post-traumatic Stress Disorder
- Interventions
- Not listed
- Lead sponsor
- International Hyperbaric Medical Foundation
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 133 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 10
- States / cities
- San Francisco, California • Boulder, Colorado • Delray Beach, Florida + 7 more
- Conditions
- Persistent Post Concussion Syndrome, Mild Traumatic Brain Injury
- Interventions
- Active tDCS, Sham tDCS
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Post-Concussion Syndrome
- Interventions
- Usual Care, C-STEP (Cognitive Behavioral Therapy)
- Behavioral
- Lead sponsor
- Sean Rose
- Other
- Eligibility
- 10 Years to 18 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Mild Traumatic Brain Injury
- Interventions
- Manualized cognitive rehabilitation for mild traumatic brain injury (mTBI)
- Procedure
- Lead sponsor
- South Texas Veterans Health Care System
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- San Antonio, Texas
- Conditions
- Post-Concussion Syndrome
- Interventions
- 50 Adipose Derived Stem Cell Infusion, 150 Adipose Derived Stem Cell Infusion, 300 Adipose Derived Stem Cell Infusion, Placebo Infusion
- Drug
- Lead sponsor
- American CryoStem Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- La Mesa, California
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Interventions
- wavelength-1 bright light, wavelength-2 bright light
- Device
- Lead sponsor
- University of Arizona
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Concussion, Brain, Concussion Post Syndrome
- Interventions
- Mindfulness Exercises and Meditations
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Mild Traumatic Brain Injury, Post Concussion Syndrome
- Interventions
- Functional near-infrared spectroscopy (fNIRS), V1 stimulation electrodes, Magnetic Resonance Imaging (MRI), MAGNUS scanner
- Device
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Post-concussive Symptoms, Traumatic Brain Injury
- Interventions
- hyperbaric oxygen, sham hyperbaric air
- Drug · Other
- Lead sponsor
- U.S. Army Medical Research and Development Command
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 5
- States / cities
- Camp Pendleton, California • Fort Carson, Colorado • Fort Gordon, Georgia + 2 more
- Conditions
- Mild Traumatic Brain Injury, Concussion, Mild, Concussion, Severe, Concussion, Intermediate
- Interventions
- RPM-assisted specialist access
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 13 Years to 18 Years
- Enrollment
- 210 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Post Concussive Syndrome
- Interventions
- Not listed
- Lead sponsor
- State University of New York - Upstate Medical University
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Syracuse, New York
- Conditions
- Concussion Post Syndrome
- Interventions
- Blood Flow Restriction Training with Exercise
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 14 Years to 30 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Traumatic Brain Injury
- Interventions
- rTMS, HD-tDCS, Attention Process Training
- Device · Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years to 59 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 5
- States / cities
- Minneapolis, Minnesota • Albuquerque, New Mexico
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis, Huntington Disease, Lewy Body Dementia, Frontotemporal Dementia, Amyotrophic Lateral Sclerosis (ALS), APOE-4 Positive, Traumatic Brain Injury, Concussion, Post-Traumatic Stress Disorder, Down Syndrome, Neuro-Degenerative Disease, Normal Cognition
- Interventions
- Retinal and Choroidal Imaging
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2026
- U.S. locations
- 1
- States / cities
- Durham, North Carolina