Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:32 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 385–408 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Interventions: diclofenac, Norco; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Ocular Inflammation and Pain
Interventions: APP13007, 0.05%, Matching Vehicle Placebo for APP13007, 0.05%; Drug
Lead sponsor: Formosa Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 378 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 34
States / cities: Scottsdale, Arizona • Glendale, California • Hemet, California + 28 more

Conditions: Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee, Knee Ligament Injury, Chondral Injury of Left Knee, Chondral Injury of Right Knee, Loose Body Knee
Interventions: Dronabinol, Placebo; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty(Postoperative Pain)
Interventions: 4 Real sessions of Transcranial Direct Current Stimulation, 2 Real Sessions of Transcranial Direct Current Stimulation, 1 Real Session of Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 19 Years to 90 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anesthesia
Interventions: Acupuncture + Standard of Care; Other
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 12 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain
Interventions: Fentanyl; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions: PT Group, Usual Care; Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pain
Interventions: Parecoxib Sodium/Valdecoxib, Placebo/Valdecoxib, Placebo/Placebo; Drug · Other
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 1,671 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 84
States / cities: Fairhope, Alabama • Mobile, Alabama • Tucson, Arizona + 61 more

Conditions: Ureteral Stent-Related Symptom, Retrograde Intra-renal Surgery
Interventions: 4.8 Fr Ureteral stents, 7 Fr Ureteral stents; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Spine Pain, Spine Surgery
Interventions: Preoperative Resistance Exercise; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2035
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Postsurgical Pain
Interventions: AYX1 Injection 660 mg / 6 mL, AYX1 Injection 1100 mg / 10 mL, Placebo Injection 6 mL, Placebo Injection 10 mL; Drug
Lead sponsor: Adynxx, Inc.; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Sheffield, Alabama • Phoenix, Arizona

Conditions: Mastectomy
Interventions: Jacki Recovery jacket, Standard Care Pain medicine/management; Device · Other
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Knee Pain, Knee Chondroplasty
Interventions: Theramine, Theramine- like placebo; Drug
Lead sponsor: Targeted Medical Pharma; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Gulf Breeze, Florida

Conditions: Obstruction of Pelviureteric Junction
Interventions: Ropivacaine wound catheter, Saline wound catheter; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Months to 14 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Boston, Massachusetts • Cincinnati, Ohio

Conditions: Arthroscopic Shoulder Surgery, Pain, Postoperative
Interventions: Extracellular Matrix Graft Injectable Implant; Device
Lead sponsor: Brian Badman; Other
Eligibility: 18 Years to 55 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Avon, Indiana

Conditions: Opioid Use
Interventions: opioid-containing analgesic, two over-the-counter analgesics; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 1,815 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 5
States / cities: Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more

Conditions: Post-surgical Pain Following Extraction of Molar Teeth
Interventions: Ibuprofen 250 mg / Acetaminophen 500 mg, Ibuprofen 250 mg, Acetaminophen 650 mg, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 568 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Chronic Pain, Widespread, Obesity, Bariatric Surgery Candidate
Interventions: Bariatric Surgery; Procedure
Lead sponsor: New York University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 3
States / cities: New York, New York

Conditions: Chronic Low-back Pain, Postsurgical Pain, Opioid Use, Lumbar Spine Surgery
Interventions: Individual telehealth mindfulness, Group telehealth mindfulness; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 90 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Wrist Injuries, Postoperative Pain Control
Interventions: 20ml bolus of 0.5% ropivicaine, 10 ml of 0.5% ropivicaine, Midazolam, Fentanyl; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Knee Injuries, Pain, Postoperative, Opioid Use
Interventions: Norco 5Mg-325Mg Tablet, Ibuprofen 600 mg, Acetaminophen 325Mg Tab; Drug
Lead sponsor: Sanford Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Surgery, Pain, Postoperative
Interventions: NSAID, Opioid, Acetaminophen; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 6
States / cities: Ann Arbor, Michigan • Detroit, Michigan • St Louis, Missouri + 3 more

Conditions: Acute Pain, Chronic Post Operative Pain, Opioid Use
Interventions: regional anesthesia, no regional anesthesia, acute pain consultation, no acute pain consultation; Procedure · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Persistent Post-surgical Pain
Interventions: Yoga, Chronic Pain Health Education; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty

Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery

Dronabinol After Arthroscopic Surgery

Dose Dependent Effects of tDCS on Post-Operative Pain

Acupuncture ACL (Anterior Cruciate Ligament)

Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

A Study Comparing the Efficacy and Safety of Valdecoxib Plus Parecoxib Versus Valdecoxib Plus Placebo for the Treatment of Pain After Coronary Artery Bypass Surgery

Impact of Ureteral Stent and Sheaths Size on Post-Operative Pain

Influence of Pre-operative Back Muscle Exercise on Post-operative Outcomes After Spine Surgery

Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery

Reduction of Post Mastectomy Pain With the Jacki® Recovery Jacket

A Randomized Double-Blind Placebo Controlled Trial to Determine the Status of Post Knee Chondroplasty Patients Administered Theramine Versus Placebo in Addition to Post Surgery Analgesics

The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine

Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery

Opioid Analgesic Reduction Study

A Safety And Efficacy Study of Ibuprofen 250 mg / Acetaminophen 500 mg In The Treatment Of Post-Surgical Dental Pain

Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults

Postoperative Telehealth Mindfulness Intervention After Spine Surgery

Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery

Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

Yoga for Persistent Post-Surgical Pain (PPSP)