Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 433–456 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Acute Pain
Interventions: Suzetrigine; Drug
Lead sponsor: Vertex Pharmaceuticals Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 17
States / cities: Scottsdale, Arizona • Little Rock, Arkansas • Sarasota, Florida + 13 more

Conditions: Outpatient Surgery, Pain, Postoperative
Interventions: Norco, Ibuprofen; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 185 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 2
States / cities: Loma Linda, California

Conditions: Lumbar Spine Surgery
Interventions: DepoDur; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Pain, Postoperative
Interventions: Intravenous Acetaminophen, Placebo; Drug · Other
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 10 Years to 18 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Post-operative Pain
Interventions: Epidural catheter; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
Interventions: SOMA pain manager smartphone application; Device
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder, Spine Injury
Interventions: Cox chiropractic care; Other
Lead sponsor: Keiser University College of Chiropractic Medicine; Other
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: West Palm Beach, Florida

Conditions: Refractive Surgery
Interventions: Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone; Drug
Lead sponsor: Vance Thompson Vision; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Mastectomy, Mastectomy Patient, Mastectomy and Breast Reconstruction, Breast Reconstruction, Breast Reconstruction After Mastectomy, Postmastectomy Pain
Interventions: PROMIS Scale v2.0 - Pain Intensity 3a, PROMIS 29+2, PROMIS Scale v2.0 - Nociceptive Pain Quality 5a, PROMIS Scale v2.0 - Neuropathic Pain Quality 5a; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 274 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Upper-extremity Surgery, Post-operative Pain
Interventions: Supraclavicular vs. Infraclavicular ropivicaine infusion; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Adenotonsillectomy, Analgesia, Surgery
Interventions: Dexamethasone, Ibuprofen, Acetaminophen, Placebo; Drug
Lead sponsor: David Chi, MD; Other
Eligibility: 3 Years to 17 Years
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania • Sewickley, Pennsylvania

Conditions: Pain
Interventions: Ibuprofen/acetaminophen, Ibuprofen, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 16 Years to 40 Years
Enrollment: 394 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Postoperative Pain
Interventions: Extended-Release liposomal bupivacaine (Exparel), Normal saline; Drug
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Hernia, Inguinal/Surgery, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions: TAP block; Procedure
Lead sponsor: Stamford Anesthesiology Services, PC; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 2
States / cities: Stamford, Connecticut

Conditions: Pain, Postoperative, Postoperative Pain, Abdominal Pain, Obesity, Pneumoperitoneum
Interventions: Intraperitoneal Aerosolization System, IntraMyst; Device
Lead sponsor: Northgate Technologies; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 2
States / cities: Elk Grove Village, Illinois • Hoffman Estates, Illinois

Conditions: Opioid Use, Enhanced Recovery After Surgery, Anesthesia, Ketamine, Pain, Postoperative
Interventions: Ketamine, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 1,570 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pain, Postoperative
Interventions: Methadone, Standard of care; Drug
Lead sponsor: Brandon Knopp; Other
Eligibility: 18 Years to 120 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Kidney Cancer, Prostate Cancer
Interventions: Lidocaine Hydrochloride 0.8% in Dextrose 5% Solution, 0.9% Sodium Chloride Injection; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Bladder Carcinoma, Post-operative Pain
Interventions: Placebo, Questionnaire Administration, Ropivacaine Hydrochloride; Other · Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Breast Cancer
Interventions: Bupivacaine, patient-reported pain scores, saline; Drug · Behavioral · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Pain, Postoperative, Shoulder Osteoarthritis
Interventions: local infiltration of liposomal bupivacaine, continuous infusion of ropivacaine interscalene nerve block; Drug · Other
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Quadratus Lumborum Block, Surgical Wound Infiltration
Interventions: Liposomal Bupivicaine, QL Block; Drug · Procedure
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Post Operative Pain
Interventions: Acetaminophen, Placebo; Drug · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Lumbar Surgery
Interventions: Provant; Device
Lead sponsor: Regenesis Biomedical, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 8
States / cities: Birmingham, Alabama • Phoenix, Arizona • Boise, Idaho + 5 more

Search by objective public record fields.

A Single-arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Selected Surgeries

Patient Narcotic Requirements After Outpatient Otolaryngology Procedures

Safety and Efficacy of DepoDur in Lumbar Spine Surgery Patients

Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients

Uniport and Multiport Epidural Catheters in Post-surgical Patients

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Prospective Study of Post Surgical Continued Spinal Pain Patients

The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study

A Study on Pain After Breast Reconstruction

Optimization of Catheter Insertion Site for Continuous Peripheral Nerve Blocks

Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity

Evaluation of the Efficacy of Novel Ibuprofen Acetaminophen Combination Formulations in the Treatment of Post-surgical Dental Pain

Efficacy of Extended-Release Liposomal Bupivacaine for Post-Operative Urogynecologic Surgery

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

Methadone for Post-operative Spine Surgery

Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery

Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain After Surgery in Patients With Bladder Cancer

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

Effective Pain Management During Shoulder Replacement Surgery With EXPAREL

Surgeon Infiltration QL Block Comparison

Acetaminophen Randomized Controlled Trial

Study of PEMF (Pulsed Electromagnetic Field) Therapy in the Treatment of Persistent Post-Operative Pain Following Lumbar Surgery