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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:24 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 505–528 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Lumbar Spine Surgery, Chronic Low-back Pain, Postsurgical Pain
Interventions: Telehealth mindfulness-based intervention (MBI), Telehealth Education; Behavioral
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Post Operative Pain, Nausea
Interventions: Dexamethasone 8mg iv x1, placebo; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Paravertebral Catheter Insertion, Mastectomy, Breast Cancer
Interventions: Placebo (normal saline) Continuous Infusion, Ropivicaine 0.4% Continuous Infusion; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Post Operative Pain, Opioid Use, Prolapse Genital
Interventions: Opioid calculator, Standard opioid prescription; Other
Lead sponsor: David Sheyn; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pain, Post-operative
Interventions: third molar surgery; Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Pain
Interventions: Exparel, Marcaine; Drug
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Coronary Artery Disease, Pain, Postoperative
Interventions: Exparel, Placebo; Drug
Lead sponsor: Peter A Knight; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Pain, Postoperative
Interventions: Intravenous Diclofenac (DIC075V), Intravenous Ketorolac, placebo; Drug
Lead sponsor: Javelin Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 14
States / cities: Birmingham, Alabama • Florence, Alabama • Montgomery, Alabama + 11 more

Conditions: Root Canal Therapy, Persistent Tooth Pain
Interventions: Not listed
Lead sponsor: Dental Practice-Based Research Network; Network
Eligibility: 19 Years to 70 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 7
States / cities: Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more

Conditions: Nasal Sinus; Inflammation, Opioid Abuse, Pain, Postoperative
Interventions: Ibuprofen 600Mg Tablet, Standard Regimen | Tylenol; Drug · Other
Lead sponsor: University of Nebraska; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Omaha, Nebraska • Cincinnati, Ohio

Conditions: Post-operative Pain, Gynecological Surgery, Acupuncture
Interventions: Acupuncture needles; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-surgical Dental Pain
Interventions: Paracetamol 1000 mg, Paracetamol 500 mg, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 2
States / cities: Austin, Texas • Salt Lake City, Utah

Conditions: Pain, Postoperative
Interventions: Celecoxib, Acetaminophen, Placebo; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 45 Years
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis, Spondylolisthesis, Back Injuries
Interventions: ACT intervention; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 22 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Chestnut Hill, Massachusetts

Conditions: Obese, Surgery, Pain, Postoperative
Interventions: Visual analog scale (VAS) assesment of pain; Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Postoperative Pain, Abdominal Surgery
Interventions: SABER-Bupivacaine, Bupivacaine HCl, SABER-Placebo; Drug
Lead sponsor: Durect; Industry
Eligibility: 18 Years and older
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 22
States / cities: Birmingham, Alabama • Florence, Alabama • Mobile, Alabama + 18 more

Conditions: Stone, Kidney, Stone Ureter
Interventions: Standard of care stent placement, No stent placement, Surveys; Device · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 792 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 16
States / cities: Tucson, Arizona • Gainesville, Florida • Indianapolis, Indiana + 12 more

Conditions: Breast Cancer, Postoperative Recovery
Interventions: ERAS Protocol, Standard Perioperative Care; Other
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Shoulder Pain
Interventions: Meloxicam 15 mg, Preoperative Interscalene Nerve Block, arthroscopic labral repair; Drug · Procedure
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pain, Postoperative
Interventions: Bupivacaine Collagen Sponge, Placebo; Drug
Lead sponsor: Innocoll; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Albany, New York

Conditions: Pain
Interventions: Ibuprofen 300 mg Oral Tablet, Ibuprofen 200 mg Oral Tablet, Placebo of PR tablet, Placebo of IR tablet; Drug
Lead sponsor: Reckitt Benckiser Healthcare (UK) Limited; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Breast Cancer
Interventions: Dexmedetomidine, Liposomal bupivacaine; Drug
Lead sponsor: United States Naval Medical Center, Portsmouth; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Portsmouth, Virginia

Conditions: ACL Tear, Post Operative Pain
Interventions: Iovera, Celecoxib, Acetaminophen, Oxycodone, Tramadol, Bupivacaine Hydrochloride, Acetaminophen 500Mg Cap; Device · Drug
Lead sponsor: Matthew Varacallo; Other
Eligibility: 15 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: DuBois, Pennsylvania

Conditions: Chronic Pain
Interventions: Not listed
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 80 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Royal Oak, Michigan • Troy, Michigan

Search by objective public record fields.

Telehealth Mindfulness After Spine Surgery

Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery

Prevention of Post-Mastectomy Breast Pain Using Ambulatory Continuous Paravertebral Blocks

Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator

Multimodal Analgesic Protocol to Moderate Acute Pain

Comparison of Local Anesthetic Infusion Pump Versus DepoFoam Bupivacaine for Pain Management

Parasternal Nerve Block in Cardiac Patients

Efficacy and Safety of IV Diclofenac (DIC075V) for Pain After Abdominal or Pelvic Surgery

DPBRN Persistent Pain and Root Canal Therapy

Pain Management Following Sinus Surgery

Acupuncture for Post-Operative Pain Control for Patients Undergoing Gynecological Surgery

Post-operative Dental Pain Study Comparing Analgesic Efficacy

Preemptive Analgesia With Celecoxib for Acute Dental Pain Management

PREventing Pain After Surgery

Does BMI Influence Pain Follow vNOTE Surgery

Bupivacaine Effectiveness and Safety in SABER® Trial

Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative

ERAS Protocols in Breast Conserving Surgery

Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery?

Efficacy and Safety of A Collagen Bupivacaine Implant in Patients After Gastrointestinal Surgery

Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars

Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies

Impact of Opioid Avoidance Protocol for ACL Reconstruction

Susceptibility to Chronic Post-Traumatic Extremity Pain