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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:56 AM EST

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Showing 577–600 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Ocular Inflammation and Pain After Cataract Surgery
Interventions: APP13007, 0.05%, Matching Vehicle Placebo for APP13007, 0.05%; Drug
Lead sponsor: Formosa Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 370 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 31
States / cities: Chandler, Arizona • Mesa, Arizona • Phoenix, Arizona + 28 more

Conditions: Total Knee Arthroplasty Revision, Inflammatory Markers, Gut Microbiota
Interventions: Assigned Interventions; Dietary Supplement
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 40 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Sore Throat, Pain
Interventions: Placebo administration, Dexamethasone 0.05mg/kr administration, Dexamethasone 0.1mg/kg; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 64 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain, Post Operative Analgesia, Opioid Consumption, Postoperative
Interventions: Lidocaine HCl 0.8% in D5W, Dextrose 5% in water; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 2,290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Cerebral Palsy, Chronic Post Surgical Pain
Interventions: Not listed
Lead sponsor: Chantel Burkitt; Other
Eligibility: 5 Years to 17 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 2
States / cities: Wilmington, Delaware • Saint Paul, Minnesota

Conditions: Postoperative Pain
Interventions: Methadone; Drug
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Evanston, Illinois

Conditions: Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Interventions: Suzetrigine (Journavx); Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Pain, Postoperative
Interventions: cryoSPHERE Ablation, Bupivacaine; Device · Drug
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years to 90 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Acute Pain
Interventions: CR845, Placebo; Drug
Lead sponsor: Cara Therapeutics, Inc.; Industry
Eligibility: 21 Years to 60 Years · Female only
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 12
States / cities: Mobile, Alabama • Sheffield, Alabama • Phoenix, Arizona + 7 more

Conditions: Pain, Shoulder, Arthroplasty
Interventions: Not listed
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 90 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Ankle Fracture
Interventions: Liposomal Bupivacaine with Bupivacaine; Drug
Lead sponsor: Jamaica Hospital Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Jamaica, New York

Conditions: Post-operative Pain
Interventions: Cannabidiol Oil; Drug
Lead sponsor: Foundation for Orthopaedic Research and Education; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Shoulder Pain, Osteoarthritis of Glenohumeral Joint, Rotator Cuff Tear Arthropathy
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 1,034 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2024
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Pediatric Postoperative Pain
Interventions: bilateral ultrasound-guided rectus sheath block, Wound infiltration; Procedure
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Years to 12 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Boston, Massachusetts • Waltham, Massachusetts

Conditions: Hip Osteoarthritis
Interventions: Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection; Procedure · Drug
Lead sponsor: Sharad Khetarpal; Other
Eligibility: 18 Years to 90 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Pain, Post-operative
Interventions: N1539, Intravenous Placebo; Drug
Lead sponsor: Baudax Bio; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 4
States / cities: Bakersfield, California • Pasadena, California • Pasadena, Maryland + 1 more

Conditions: Morbid Obesity
Interventions: Not listed
Lead sponsor: William Beaumont Army Medical Center; Federal
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: El Paso, Texas

Conditions: Pain, Postoperative
Interventions: PMI-150 (intranasal ketamine), Placebo; Drug
Lead sponsor: Hospira, now a wholly owned subsidiary of Pfizer; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 16
States / cities: Birmingham, Alabama • Florence, Alabama • Sheffield, Alabama + 13 more

Conditions: Pain, Morphine Adverse Reaction
Interventions: Epidural Morphine, Epidural Saline; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Chronic Pain Post-Procedural
Interventions: Senza HF10 Therapy; Device
Lead sponsor: Nevro Corp; Industry
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Greenfield, Wisconsin

Conditions: Postoperative Pain
Interventions: HTX-011B, Placebo, HTX-011A, HTX-002, Bupivicaine HCl; Drug
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 277 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 8
States / cities: Phoenix, Arizona • Pasadena, California • Pasadena, Maryland + 3 more

Conditions: Acute Pain, Surgery
Interventions: Prescription by surgical team, Recommendation by surgical team; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pain, Post Operative, Anxiety, Opioid Use
Interventions: Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS); Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 70 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Coronary Artery Diseases, Valvular Heart Diseases
Interventions: Reiki/manual therapy; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 272 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Search by objective public record fields.

Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery Including a Corneal Endothelial Cell Sub-study

Fiber Smoothie Supplement

Post Operative Sore Throat and Dexamethasone

The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery

Chronic Postsurgical Pain

Intraoperative Methadone for Postoperative Pain Control After Thoracic Surgery

Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture

Cryoablation of Intercostal Nerves for Post-Operative Pain Management in Opioid-Tolerant Patients

Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

Comparison of Pain Relief After Non Stimulating Interscalene Catheter Placement vs Stimulating Catheter Placement in Total Shoulder Arthroplasty.

Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)

CBD Knee Scope Study

Functional and Radiographic Outcomes After Shoulder Surgery

Postoperative Pain After Pediatric Umbilical Hernia Repair

Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement

Evaluation of N1539 Following Bunionectomy Surgery

OnQ Pain Pump Effectiveness in Post Operative Pain Control in Bariatric Patients

Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery

Two Dose Epidural Morphine for Post-cesarean Analgesia

HF10 Treatment of Chronic Knee Pain

Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery

Prescribing Vs. Recommending Over-The-Counter (PROTECT) Analgesics for Patients with Postoperative Pain:

Music Therapy in the Treatment of Perioperative Anxiety and Pain

Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery