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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:17 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 625–648 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Postoperative Pain, Patient Satisfaction, Analgesia
Interventions: Not listed
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Pain
Interventions: Vitrase (ovine hyaluronidase) Lyophilized; Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Anxiety, Pain, Surgery
Interventions: Galacto-Oligosaccharide, Maltodextrin (Placebo); Drug
Lead sponsor: Jeff Taekman, M.D.; Other
Eligibility: 21 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Sports Medicine Injuries
Interventions: LCS (Life Care Specialist), Standard of Care; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 15 Years to 45 Years
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Pain Management
Interventions: video-guided acupuncture imagery treatment (VGAIT), Education video; Other
Lead sponsor: Jingping Wang, MD, Ph.D.; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Spinal Fusion
Interventions: Virtual Reality; Device
Lead sponsor: Gillette Children's Specialty Healthcare; Other
Eligibility: 6 Years to 17 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Interventions: Music and Guided Imagery, Control, Music Only; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Congenital Heart Disease
Interventions: continuous infusion, as needed dosing, Acetaminophen, ketorolac; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 3 Months to 4 Months
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Oak Lawn, Illinois

Conditions: Psychological Distress, Intra-abdominal Cancer
Interventions: Mindfulness Intervention, Non-mindfulness Intervention; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Total Knee Arthroplasty (Postoperative Pain)
Interventions: ATX101, bupivacaine hydrochloride, saline placebo; Drug
Lead sponsor: Allay Therapeutics, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 11
States / cities: Little Rock, Arkansas • Tamarac, Florida • Atlanta, Georgia + 7 more

Conditions: Pain
Interventions: effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets, placebo; Drug
Lead sponsor: Wyeth is now a wholly owned subsidiary of Pfizer; Industry
Eligibility: 16 Years to 40 Years
Enrollment: 270 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Post-operative Pain, Sinus Surgery
Interventions: Acetaminophen 325 mg Oral Tablet, Acetaminophen 650 mg Oral Tablet, OxyCODONE 5 mg Oral Tablet, Acetaminophen/Hydrocodone 325 mg/7.5 mg oral tablet; Drug
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Farmington Hills, Michigan

Conditions: Dental Pain
Interventions: Naproxen Test, Naprosyn, Placebo; Drug
Lead sponsor: Iroko Pharmaceuticals, LLC; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 254 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Pain, Postoperative
Interventions: Bupivacaine Hydrochloride, Saline; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 19 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain
Interventions: Transitional Pain Service; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Post-operative Pain
Interventions: Pregabalin, Placebo (for Pregabalin); Drug
Lead sponsor: Legacy Health System; Other
Eligibility: 18 Years to 70 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Interventions: Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine, Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.; Procedure · Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pain, Low Back 'Spine Fusion' Surgery
Interventions: Acupuncture therapies, Control; Procedure
Lead sponsor: Beth Israel Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Postoperative Ocular Inflammation, Postoperative Ocular Pain
Interventions: Sham (No Treatment), TRIESENCE (triamcinolone acetonide injectable suspension); Procedure · Drug
Lead sponsor: Harrow Inc; Industry
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Acute Pain, Surgery
Interventions: NeuroIDgenetix Test Panel; Genetic
Lead sponsor: AltheaDx; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Anesthesia
Interventions: Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter; Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 65 Years
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Revision Spine Surgery, Fusion of Spine, Cervical Fusion, Lumbar Fusion
Interventions: Ketamine Hydrochloride; Drug
Lead sponsor: AXIS Spine Center- a division of Northwest Specialty Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Coeur d'Alene, Idaho

Conditions: Shoulder Pain
Interventions: Superficial Cervical Plexus Block, Bupivacaine; Procedure · Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Pain, Postoperative, Substance Use
Interventions: iPAWS, Educational Materials; Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 15 Years to 20 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Search by objective public record fields.

Post Operative Analgesia and Patient Satisfaction

Evaluation of Vitrase as an Adjuvant to Increase Absorption and Dispersion of Other Injected Anesthetics

Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition

Effect of Personalized Pain Coaches After Orthopaedic Surgery for Patients With Sports Medicine Injuries

Imagined Acupuncture for Postoperative Pain After Spinal Surgery

Virtual Reality for Post-operative Pain Management

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

Continuous Infusion Versus Bolus Dosing for Pain Control After Pediatric Cardiothoracic Surgery

Structured Post-Operative Pain and Distress Treatment Intervention for Patients Undergoing Surgery for Intra-Abdominal Malignancies

Phase 2B Study Assessing Pain Relief After Replacement of the Knee

Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain

Postoperative Pain Control in Septum and Sinus Surgery

Study of Naproxen Capsules to Treat Dental Pain

Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery

Prospective Randomized Study of TPS + CBT VS TPS Alone: Readmission, Opioid Use, and Chronic Pain

Preoperative Pain Control in Gastric Bypass Surgery Patients

Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength

'Acupuncture Therapy' for Pain and Function Recovery in Spine Surgery Patients

A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery

Clinical Study to Evaluate Clinical Impact of PGx-Guided Treatment for Patients Undergoing Elective Spinal Surgical Procedures

Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery

Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery

iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery