Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 3:23 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Healthy, Inflammation
Interventions: etanercept (Enbrel); Drug
Lead sponsor: National Institute of Dental and Craniofacial Research (NIDCR); NIH
Eligibility: Not listed
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Hernia
Interventions: Quantitative Sensory Testing; Procedure
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pain, Postoperative
Interventions: Liposomal bupivacaine, Bupivacain, Epinephrin; Drug
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: San Diego, California

Conditions: Postoperative Pain, Acute Pain
Interventions: Tapentadol; Drug
Lead sponsor: Grünenthal GmbH; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Postoperative Pain
Interventions: Liposomal bupivacaine, Standard of care; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 2
States / cities: Madison, Wisconsin

Conditions: Umbilical Hernia
Interventions: Bupivacaine; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 5 Years to 17 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pain
Interventions: Novel Ibuprofen, Acetaminophen, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 16 Years to 40 Years
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Opioid Use
Interventions: NOMO Protocol; Drug
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older · Female only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Pelvic Organ Prolapse, Postoperative Pain Management, Gynecologic Surgeries
Interventions: Sitz Bath; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery, Knee Injuries, Knee Pain Chronic, Postoperative Pain, Chronic Postoperative Pain
Interventions: SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared); Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Pain
Interventions: Exparel, Indwelling Interscalene Catheter; Drug · Device
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 40 Years to 74 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Post-operative Pain
Interventions: Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine); Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Breast Cancer, Chronic Pain
Interventions: No intervention; Other
Lead sponsor: University of Florida; Other
Eligibility: 40 Years to 75 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Post Surgical Ocular Inflammation
Interventions: TRS01 eye drops, Placebo eye drops; Drug
Lead sponsor: Tarsier Pharma; Industry
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 5
States / cities: Inglewood, California • Petaluma, California • Washington, Missouri + 2 more

Conditions: Elective Spine Surgery Receiving Pre and/or Postoperative Pain Control With Opioids
Interventions: Opioid and Benzodiazepine Naive-patients, Opioid and Benzodiazepine Tolerant-patients; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 21 Years to 75 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Postmastectomy Lymphedema Syndrome, Pain, Shoulder Mobility Impairment, Breast Surgery
Interventions: Myofascial Massage Therapy, Global Relaxation Massage; Other
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 21 Years to 79 Years · Female only
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Back Pain, Surgery-Complications, Narcotic Use, Physical Stress, Post Operative Pain
Interventions: Exparel, Bupivacain; Drug
Lead sponsor: Foundation for Orthopaedic Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Post Operative Pain Control, Narcotic Use, Pelvic Organ Prolapse, Urinary Incontinence , Stress, Surgery
Interventions: Sprix; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Pain, Post-operative
Interventions: N1539, Intravenous Placebo; Drug
Lead sponsor: Baudax Bio; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Pasadena, Maryland

Conditions: Spinal Fusion, Chronic Lower Back Pain
Interventions: Laser Diode Brace, Sham Laser Diode Brace; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Postoperative Pain, Anxiety Postoperative, Opioid Use
Interventions: Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG, Essence Olfactory Necklace, Bedside Olfaction Device; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Postoperative, Chronic Pain, Pain Catastrophizing, Pain, Acute
Interventions: Online mindfulness-based cognitive therapy, Online standardized education; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Thyroidectomy, Parathyroidectomy, Opioid Use, Pain, Postoperative
Interventions: Quality improvement bundle; Other
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Acute Pain
Interventions: DFN-15 (Celecoxib Oral Solution) 62.5 mg, DFN-15 (Celecoxib Oral Solution) 125 mg, DFN-15 (Celecoxib Oral Solution) 250 mg, Placebo; Drug
Lead sponsor: Dr. Reddy's Laboratories Limited, India; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Salt Lake City, Utah

Search by objective public record fields.

Etanercept (Enbrel) to Treat Pain and Swelling After Third Molar Extraction

Quantitative Sensory Testing and Analysis of Post Inguinal Hernia Surgery Pain

Multimodal Orthognathic Study Comparing Use of Exparel With Standard of Care.

Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain

Optimizing Recovery in Abdominoplasty

Analgesic Efficacy After Umbilical Hernia Repair in Children

Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain

Does a Non-Opioid Multimodal Pain (NOMO) Protocol Decrease Narcotic Use

SORE Study: Sitz Baths After Urogynecologic Reconstruction

Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery

Exparel Interscalene vs Indwelling Catheter

Comparing Perioperative Outcomes in Pain Control

Persistent Post-Surgical Pain in Women With BrCA

A Study of TRS01 in Participants With Post-surgical Ocular Inflammation

Impact of Daily, Digital and Behavioral Tele-health Tapering Program for Perioperative Surgical Patients Exposed to Opioids and Benzodiazepines.

Massage for Post Breast Surgery

Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion

Sprix for Postoperative Pain Control Following Gynecologic Surgery

Placebo-Controlled Evaluation of N1539 Following Bunionectomy Surgery

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery

Online Mindfulness-based Intervention to Prevent Chronic Pain

Opioid Use After Thyroid and Parathyroid Surgeries

Efficacy, Tolerability, Safety, and Pharmacokinetic Study of DFN-15