Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:42 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Opioid Use, Unspecified
Interventions: Ropivacaine, Dexmedetomidine, Dexamethasone; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Post-operative Pain
Interventions: Pulsed Radiofrequency Energy (PRFE), No Pulsed Radiofrequency Energy (PRFE); Device
Lead sponsor: Regenesis Biomedical, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 3
States / cities: Pasadena, California • Pasadena, Maryland • San Antonio, Texas

Conditions: Pain, Postoperative, Non-Opioid Pain Management, Virtual Reality
Interventions: Virtual Reality; Device
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic, Postoperative Pain
Interventions: Bupivacaine-epinephrine, Normal saline; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: Endometriosis
Interventions: Bupivacaine Hydrochloride, Normal saline; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Opioid Use
Interventions: Information Sheet, Deterra Drug Deactivation System; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 391 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Opioid Use, Kidney Diseases, Pain, Postoperative, Postoperative Complications, Postoperative Nausea and Vomiting
Interventions: multimodal pain management, goal directed fluid management, preoperative carbohydrate loading, Donor nephrectomy, regional anesthesia; Procedure · Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Scoliosis
Interventions: Bupivacaine, Normal Saline; Drug
Lead sponsor: Shriners Hospitals for Children; Other
Eligibility: 8 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Postoperative Pain
Interventions: Perioperative Pain Self-management (PePS); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 100 Years
Enrollment: 401 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Iowa City, Iowa • Minneapolis, Minnesota

Conditions: Surgery
Interventions: .9 normal saline placebo, Group L (lidocaine); Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 64 Years · Female only
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain, Postoperative
Interventions: Not listed
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 85 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pelvic Organ Prolapse
Interventions: LigaSureTM vessel sealing device; Device
Lead sponsor: Marlana McDowell; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Urogynecologic Surgery
Interventions: Not listed
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis, Pain, Postoperative, Ileus, Ileus Paralytic, Ileus; Mechanical, Constipation Drug Induced, Constipation, Rectum Cancer, Rectum Neoplasm
Interventions: Acetaminophen, Gabapentin, Orphenadrine, Lidocaine, Marcaine, Ketamine, Methadone, Tramadol, Ketorolac, Morphine Sulfate, Fentanyl, Dilaudid, Hydrocodone-Acetaminophen Tab 5-325 MG, HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET; Drug
Lead sponsor: University of Illinois College of Medicine at Peoria; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Peoria, Illinois

Conditions: Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
Interventions: Ropivacaine 0.2% Injectable Solution; Drug
Lead sponsor: Texas Scottish Rite Hospital for Children; Other
Eligibility: 13 Years to 21 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Frisco, Texas

Conditions: Pain, Postoperative, Gingival Diseases
Interventions: amnion-chorion membrane, Sutures; Device · Procedure
Lead sponsor: Harvard Medical School (HMS and HSDM); Other
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postoperative Pain
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 80 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Pain, Total Knee Arthroplasty
Interventions: Dexamethasone, Ropivacaine; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Surgical Procedure, Unspecified
Interventions: Conversation Guide + Clinical Support; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 81,938 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Shoulder Pain, Hiatal Hernia
Interventions: Resteck Shiatsu Neck and Back Massager, Marcaine; Device · Drug
Lead sponsor: Norton Thoracic Institute; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Postoperative Pain, Objective Assessment of Sedation
Interventions: Anesthesia Premedication, Induction and Maintenance, Pupillometry after administration of anesthetic drugs; Drug · Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 99 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use, Opioid Abuse, Uncomplicated, Opioids; Harmful Use, Analgesic Drug Dependence, Orthopedic Disorder
Interventions: Questionnaire; Other
Lead sponsor: St. Louis University; Other
Eligibility: 10 Years to 100 Years
Enrollment: 223 participants
Timeline: 2017 – 2018
U.S. locations: 3
States / cities: St Louis, Missouri

Conditions: Hysterectomy, Gynecologic Surgical Procedures, Narcotic Use, Pain, Postoperative
Interventions: Ropivacaine Infusion from ON-Q Pump, Ropivacaine + Ketorolac Infusion from ON-Q Pump, Normal Saline Infusion from ON-Q Pump; Drug
Lead sponsor: Ying Liu; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2026
U.S. locations: 2
States / cities: Washington D.C., District of Columbia

Conditions: Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction, Anesthesia, Pain
Interventions: Dexmedetomidine, Acetaminophen, Ketorolac, Morphine; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Years to 17 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Waltham, Massachusetts

Search by objective public record fields.

the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block

Pulsed Radiofrequency Energy to Treat Post-Bunionectomy Pain

Virtual Reality After Breast Reconstruction Surgery

Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis

Pain and Medication Use Following Surgery

Enhanced Recovery After Surgery in Kidney Transplant Donors

Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery

The Perioperative Pain Self-Management Program Trial

Lidocaine and Prevention of Chronic Pain

Flexibility of Cognition And Persistent Pain

Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery

Post-Operative Pain Management With NSAIDS

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population

Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery

Efficacy of Intrathecal Oxytocin to Speed Recovery After Hip Surgery

Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic

Non-pharmacological Pain Management After Surgery

Pain Relief After Hiatal Hernia Repair Surgery

Infrared Pupillometry During General Anesthesia to Predict Pain

A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries

Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery