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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post-traumatic Stress Clear all
Completed Not applicable Interventional Results available

Trauma-informed Collaborative Care for Low-income African Americans With PTSD

NCT03591107
View directory record Official record
Conditions
PTSD
Interventions
PTSD Care Management (PCM), Minimally Enhanced Usual Care (MEU)
Other
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Results available

CAP-Ketamine for Antidepressant Resistant PTSD

NCT02655692
View directory record Official record
Conditions
PTSD, Posttraumatic Stress Disorder
Interventions
Ketamine, Placebo/Saline
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
West Haven, Connecticut • Minneapolis, Minnesota • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

In-Home Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD)

NCT03110302
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Prolonged exposure
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional

Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center

NCT06210711
View directory record Official record
Conditions
Traumatic Injury, PTSD, Posttraumatic Stress Disorder
Interventions
Treatment as Usual, Brief Prolonged Exposure Therapy
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Dallas, Texas • Temple, Texas • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Active, not recruiting Not applicable Interventional

Circadian Influence on Prolonged Exposure Therapy for PTSD

NCT05453162
View directory record Official record
Conditions
PTSD
Interventions
Prolonged Exposure Therapy for Posttraumatic Stress Disorder
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era

NCT00958061
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Depression, Diabetes, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Female only
Enrollment
4,219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Charleston, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2021 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational

Long-Term Safety and Effectiveness of MDMA-Assisted Therapy for PTSD

NCT05066282
View directory record Official record
Conditions
PTSD
Interventions
Not listed
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NightWare and Cardiovascular Health in Veterans With PTSD

NCT06419959
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction, Veteran
Interventions
NightWare
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 88 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Equine Assisted Activities on Veterans With Post-traumatic Stress Disorder

NCT04850573
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
equine assisted activities
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Meditation for Emotional Numbing in Post-Traumatic Stress Disorder

NCT02163941
View directory record Official record
Conditions
Prolonged Post-traumatic Stress Disorder
Interventions
Compassion Training
Behavioral
Lead sponsor
Emory University
Other
Eligibility
25 Years to 65 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)

NCT01391832
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Processing Therapy, Repetitive Transcranial Magnet Stimulation (rTMS)
Device · Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 60 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational

Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders

NCT04060121
View directory record Official record
Conditions
IBS - Irritable Bowel Syndrome, Constipation
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Results available

The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD

NCT00896038
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence, Posttraumatic Stress Disorder
Interventions
Aprepitant, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 50 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Telephone-based Care for OEF/OIF Veterans With PTSD

NCT00680524
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Phone-based outreach
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Development and Evaluation of a Tonic Immobility Focused Psychoeducational Intervention

NCT05113277
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Tonic Immobility Response
Interventions
Tonic Immobility Psychoeducation (TIP), Health Education Training (HET)
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PET Imaging of mGLuR5 With Drug Challenge

NCT01691092
View directory record Official record
Conditions
Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD)
Interventions
Ketamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Suspended Phase 2 Interventional Accepts healthy volunteers

Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine

NCT05948553
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Intervention A Fluoxetine Hydrochloride (HCl), Intervention A Placebo
Drug
Lead sponsor
Global Coalition for Adaptive Research
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
9
States / cities
Miami, Florida • Atlanta, Georgia • Tripler AMC, Hawaii + 6 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

CCTAP: Cognitive Control Training for Treatment of AUD-PTSD

NCT03200028
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Terminated No phase listed Observational

Role of NSI in Differentiating Between Mild Traumatic Brain Injury And Behavioral Health Conditions

NCT01502839
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
Interventions
No Intervention
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
887 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

NCT07115030
View directory record Official record
Conditions
Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
Interventions
PCT+2HOPE
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Bridgeport, Connecticut • Enfield, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Withdrawn Not applicable Interventional

Feasibility Open Label Study Evaluating The Use Of Process-Instructed Self Neuro-Modulation (PRISM) For Post-Traumatic Stress Disorder

NCT04496557
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
PROCESS-INSTRUCTED SELF NEURO-MODULATION (PRISM)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Omega-3 Fatty Acids and Post Traumatic Stress Disorder (PTSD)

NCT00644423
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Omega-3 Fatty Acid, Placebo
Drug
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational

An Investigation of the Biological and Neuronal Mechanisms of Post Traumatic Stress Disorder, Depression and Post-Concussive Syndrome Onset Following a Traumatic Brain Injury

NCT02019654
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD, Depression
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 5, 2022 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Role of Substance P in Post-Traumatic Stress Disorder

NCT00102102
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
[18F]SPA-RQ
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 25, 2026, 9:10 AM EDT