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Conditions: PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
Interventions: 1-(2-[+F]fluoroethyl)-L-tryptophan; Drug
Lead sponsor: Wayne State University; Other
Eligibility: 19 Years to 69 Years
Enrollment: 100 participants
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania, Panic Disorder, Social Phobia, Generalized Anxiety Disorder, Depression, Post-Traumatic Stress Disorder, Attention Deficit Hyperactivity Disorder, Eating Disorder, Specific Phobia, General Medical Condition
Interventions: Cognitive behavioral therapy (CBT); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stress Disorders, Post-Traumatic
Interventions: EFT (Emotional Freedom Techniques); Behavioral
Lead sponsor: Soul Medicine Institute; Other
Eligibility: 18 Years to 80 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Santa Rosa, California

Conditions: Major Depressive Disorder, Post-Traumatic Stress Disorder, Bipolar Disorder
Interventions: Cognitive Testing, MRI, PET; Behavioral · Other · Radiation
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: PTSD, Stress, Psychological, Gunshot Wound
Interventions: Screening Tool for Relief of Trauma (START), standard of care; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning, Chronic Medical Conditions, Chronic Medical Condition, Chronic Medical Illness, Posttraumatic Stress Disorder PTSD, Posttraumatic Stress Disorders, Posttraumatic Stress Symptoms, Posttraumatic Stress
Interventions: Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual, Structured Psychotherapy for Adolescents Responding to Chronic Stress - Individual; Behavioral
Lead sponsor: Anthony Vesco; Other
Eligibility: 8 Years to 18 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder, Posttraumatic Stress Disorder, Delayed Onset, Sleep Disturbance, Nightmare, Irritable Mood, Anger, Combat and Operational Stress Reaction, Combat Stress Disorders, Military Family, Military Operations, Emotional Regulation, Emotion Processing
Interventions: Art Therapy; Behavioral
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years to 64 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Bethesda, Maryland • Fort Belvoir, Virginia

Conditions: Depressive Disorder, Treatment-Resistant, Stress Disorders, Post-Traumatic
Interventions: Ketamine; Drug
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Stress Disorders, Post-Traumatic, Marijuana Abuse
Interventions: Personalized Feedback Session (PFS); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: San Diego, California

Conditions: TBI, Anxiety, PTSD, Depression
Interventions: CES Therapy; Device
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older · Male only
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Anxiety, PTSD, Depression
Interventions: H.O.O.V.E.S. Healing Intensives; Behavioral
Lead sponsor: VA Salt Lake City Health Care System; Federal
Eligibility: 18 Years to 120 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Posttraumatic Stress Disorder, Depressive Symptoms, Burn Out, Anxiety, Work Related Stress
Interventions: WET; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Traumatic Injury, Posttraumatic Stress Disorder, Depression, Social Determinants of Health
Interventions: CHW support; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Intimate Partner Violence (IPV)
Interventions: RISE, Advocacy-based ECAU; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 3
States / cities: Boston, Massachusetts • Minneapolis, Minnesota • Philadelphia, Pennsylvania

Conditions: Burn-Out Syndrome, Post-Traumatic Stress Disorder, Depression, Anxiety
Interventions: Visual Arts, Music, Dance/Movement, Writing/Poetry, Control; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 85 Years
Enrollment: 195 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Stress Disorders, Post-Traumatic
Interventions: Mindfulness-based exercise; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 21 Years and older
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
Interventions: Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder; Device · Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tuscaloosa, Alabama

Conditions: Traumatic Brain Injury, PTSD, Depression
Interventions: Not listed
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Depressive Disorder
Interventions: PEER Interactive Report; Device
Lead sponsor: MYnd Analytics; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 1,922 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 2
States / cities: Bethesda, Maryland • Fort Belvoir, Virginia

Conditions: Traumatic Brain Injury
Interventions: Global Z-Score Neurofeedback Training; Behavioral
Lead sponsor: The Defense and Veterans Brain Injury Center; Federal
Eligibility: 18 Years to 50 Years
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Fort Carson, Colorado

Conditions: Stress Disorders, Post-Traumatic, Bulimia Nervosa
Interventions: Prazosin, Placebo; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Post Traumatic Stress Disorder, Suicidal Ideation, Nightmares
Interventions: Prazosin, Placebo; Drug
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
Interventions: Morning Bright Light Therapy, Negative Ion Generator; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression, Cognitive Change
Interventions: 4-week MBAT, 2-week MBAT; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Coral Gables, Florida

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Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study

Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals

Gene Expression Correlates of Post-Traumatic Stress Disorder (PTSD) Symptom Change After EFT (Emotional Freedom Techniques)

Examination of Glutamate and mGluR5 in Psychiatric Disorders

Relief of Symptoms of Post-traumatic Stress for Victims of Gun Violence

Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

Ketamine Infusions for PTSD and Treatment-Resistant Depression

Applying Mixed Methods to Identify Links Between PTSD Symptoms, Cannabis Use, and Functional Behaviors With Personalized Feedback Intervention Development

Cranial Electrotherapy Stimulation (CES) Therapy

Evaluation of the H.O.O.V.E.S. Healing Intensives Program

Written Exposure Therapy for Nurses

CHW-Enhanced Trauma Recovery

RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV

Creative Arts Program to Reduce Burnout in Healthcare Professionals

Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)

Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders

An Investigation of the Biological and Neuronal Mechanisms of Post Traumatic Stress Disorder, Depression and Post-Concussive Syndrome Onset Following a Traumatic Brain Injury

Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression

Neurofeedback Technology (GZNT) for Persistent Post-Concussive Symptoms in Soldiers

Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD

Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)

Improving Sleep in Veterans With the Polytrauma Clinical Triad

Mindfulness Training in U.S. Army Cohorts