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ClinicalTrials.gov public records Last synced Sep 30, 2026, 5:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 51 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Postoperative Anxiety Clear all
Recruiting No phase listed Observational

Fear and Anxiety in Anesthesia-Naïve Patients Pre-operatively vs Post-operatively

NCT07559461
View directory record Official record
Conditions
Anxiety, Anesthesia Awareness
Interventions
Survey using a questionnaire.
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Green Light for Post-Operative Wellness

NCT07218289
View directory record Official record
Conditions
Surgery
Interventions
Bright Green Light Therapy, Dim White Light Therapy
Device
Lead sponsor
Rebecca E Kotcher, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Listening as a Postanesthesia Care Unit (PACU) Nursing Intervention

NCT04596917
View directory record Official record
Conditions
Prostate Cancer
Interventions
Preferred music listening, Relaxation breathing narrative over hypnotic music listening
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Sep 30, 2026, 5:50 AM EDT
Not yet recruiting Not applicable Interventional

Brief Postoperative Pain Management Intervention: Meaning Making Amendment

NCT07676500
View directory record Official record
Conditions
Pain, Acute, Anxiety Acute
Interventions
Mindfulness + Meaning Making Questions, Mindfulness + Implementation Questions
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
576 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Binaural Beats for Postoperative Pain and Anxiety Reduction

NCT07437469
View directory record Official record
Conditions
TKA, THA, Anxiety, Binaural Beats, Music Exposure, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Total Knee Replacement, Total Hip Replacement
Interventions
Binaural Beats Audio Intervention, Music of Choice
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Music Therapy in the Treatment of Perioperative Anxiety and Pain

NCT05263635
View directory record Official record
Conditions
Pain, Post Operative, Anxiety, Opioid Use
Interventions
Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 30, 2026, 5:50 AM EDT
Withdrawn Not applicable Interventional

Longitudinal Virtual Reality Use in Pediatric Surgical Procedures

NCT03832478
View directory record Official record
Conditions
Anxiety, Pain, Pain, Postoperative
Interventions
Virtual Reality Headset Given
Device
Lead sponsor
Stanford University
Other
Eligibility
5 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Sep 30, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery

NCT07026786
View directory record Official record
Conditions
Pain After Surgery, Anxiety After Surgery
Interventions
Mindfulness Intervention
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

NCT05658796
View directory record Official record
Conditions
Mood Disorders, Anxiety, Depressive Symptoms, Depression, Anxiety Disorders, Anxiety Depression
Interventions
-RxWell
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

NCT06783946
View directory record Official record
Conditions
Kidney Stone, Pain, Postoperative, Anxiety Postoperative
Interventions
Meditation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Phase 4 Interventional Results available

Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

NCT02213900
View directory record Official record
Conditions
Delirium, Cognitive Impairment, Post-traumatic Stress Disorder, Depression, Anxiety
Interventions
Haloperidol, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional

FOREVR Peds VR Pilot

NCT04556747
View directory record Official record
Conditions
Pain, Postoperative, Pain, Anxiety
Interventions
VR - Distraction, VR - Biofeedback
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 21 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Preventing Persistent Pain and Reducing Depressive and Anxious Symptoms Following Mastectomy and Lumpectomy

NCT03430765
View directory record Official record
Conditions
Persistent Postsurgical Pain, Breast Cancer Female, Ductal Carcinoma in Situ
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Katherine Hadlandsmyth
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Preoperative Gabapentin for Post-tonsillectomy Pain in Children

NCT01707420
View directory record Official record
Conditions
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Interventions
Gabapentin, liquid placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 16 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Pragmatic Research eXamining Inpatient Symptoms

NCT01988194
View directory record Official record
Conditions
Postoperative Pain, Nausea, Vomiting, Anxiety, Depression
Interventions
Acupuncture
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Sep 30, 2026, 5:50 AM EDT
Enrolling by invitation Not applicable Interventional

Impact of Immersive Video Education on Cardiothoracic Surgery Anxiety and Outcomes

NCT07222839
View directory record Official record
Conditions
Anxiety
Interventions
Visually Immersive Video, Standard of Care
Behavioral
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Early Phase 1 Interventional Results available

Caffeine and Neurologic Recovery Following Surgery and General Anesthesia

NCT03577730
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Caffeine Citrate, Dextrose Water
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Sep 30, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Weighted Blankets for Postsurgical Pain

NCT05324254
View directory record Official record
Conditions
Pain, Postsurgical
Interventions
Weighted blanket
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

NCT07715591
View directory record Official record
Conditions
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Interventions
Music and Guided Imagery, Control, Music Only
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Terminated Phase 3 Interventional

Effect of Music on Pain and Anxiety After Surgery

NCT01409044
View directory record Official record
Conditions
Postop Adult ICU Patients
Interventions
Music
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 99 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Sep 30, 2026, 5:50 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition

NCT02953691
View directory record Official record
Conditions
Anxiety, Pain, Surgery
Interventions
Galacto-Oligosaccharide, Maltodextrin (Placebo)
Drug
Lead sponsor
Jeff Taekman, M.D.
Other
Eligibility
21 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Sep 30, 2026, 5:50 AM EDT
Not yet recruiting Not applicable Interventional

Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing Pancreatectomy

NCT07608458
View directory record Official record
Conditions
Hepatocellular Carcinoma, Pancreas Cancer, Biliary Tract Neoplasms
Interventions
Actigraphy, Online Mindfulness Meditation, Smartphone Application-based Intervention, Survey Administration
Other · Behavioral
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Healing Touch After Cesarean

NCT05053360
View directory record Official record
Conditions
Pain, Postoperative, Anxiety, Postpartum Complication
Interventions
Healing Touch, Control
Behavioral · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Leesburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 30, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

An Innovative Tailored Intervention for Improving Children's Postoperative Recovery (WebTIPS)

NCT03730259
View directory record Official record
Conditions
Anxiety, Pain, Postoperative Behavior
Interventions
Web-based Tailored Intervention Preparation for Surgery
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Year to 12 Years
Enrollment
1,274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Orange, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 30, 2026, 5:50 AM EDT