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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Postoperative Infection Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Nitrofurantoin and Urinary Tract Infections (UTIs)

NCT00678041
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Nitrofurantoin, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Sep 25, 2026, 9:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Myometrial Biopsy for the Detection of Infection

NCT00782665
View directory record Official record
Conditions
Infection
Interventions
Biopsy
Procedure
Lead sponsor
The Woman's Hospital of Texas
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2008 · Synced Sep 25, 2026, 9:10 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Opioid-Free Anesthetic for Tonsillectomy

NCT04528173
View directory record Official record
Conditions
Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder, Surgery
Interventions
Ketorolac, Dexmedetomidine, Morphine, Fentanyl
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Comparison of UGBRS Block and Local Infiltration

NCT02352519
View directory record Official record
Conditions
Appendicitis
Interventions
UGBRSB, Local Infiltration
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2015 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Results available

Povidone-Iodine for Nasal Decolonization

NCT05529173
View directory record Official record
Conditions
Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
Interventions
Povidone-Iodine 10%, 0.9% NaCl Solution
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection

NCT01235546
View directory record Official record
Conditions
Endometritis, Wound Infection, Abscess, Surgical Site Infection
Interventions
Azithromycin and standard of care, Placebo and standard of care
Drug
Lead sponsor
Alan Tita
Other
Eligibility
14 Years and older · Female only
Enrollment
2,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
9
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Jackson, Mississippi + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Active, not recruiting Phase 4 Interventional

Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery

NCT04580472
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Cephalexin, Placebo capsules
Drug · Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
574 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational

CALYPSO Pilot Study: Machine Learning Based Predictions of Surgical Complications

NCT02828475
View directory record Official record
Conditions
Complication of Surgical Procedure, Postoperative Infection
Interventions
CALYPSO, Standard Care
Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

NCT03720301
View directory record Official record
Conditions
Pharyngitis, Dysphonia
Interventions
Osteopathic Manipulation Treatment, Sham
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Not yet recruiting Phase 4 Interventional

PRevention Of Trauma-related Infections Through an Embedded Clinical Trials Network

NCT06920147
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Ertapenem, Cefazolin and Metronidazole.
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Comparison of Nasal Steroids After FESS in CRSwNP

NCT02194062
View directory record Official record
Conditions
Sinusitis, Nasal Polyps
Interventions
fluticasone nasal spray, Budesonide head upright, Budesonide head forward
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
2
States / cities
New Haven, Connecticut • Stratford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Terminated Not applicable Interventional

A Geriatric Home Visit Program to Reduce Post-Hip Fracture Complications

NCT02058329
View directory record Official record
Conditions
Fracture, Infection, Depression, Gait Instability, Debility
Interventions
Home Visit
Other
Lead sponsor
Northwell Health
Other
Eligibility
65 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2014 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections

NCT05920122
View directory record Official record
Conditions
Surgical Site Infection, Cesarean Section; Infection
Interventions
2% Chlorhexidine gluconate with 70% alcohol, 4% Chlorhexidine Gluconate aqueous solution
Drug
Lead sponsor
Hyagriv Simhan
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,398 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Checklist to Prevent MRSA Surgical Site Infections

NCT02216227
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Mupirocin, Chlorhexidine gluconate, Cefazolin, Vancomycin, Nasal Povidone Iodine
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
23,005 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
11
States / cities
Miami, Florida • Iowa City, Iowa • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does Straight Catheterization in Short Gynecologic Procedures Cause Bacteriuria?

NCT01926756
View directory record Official record
Conditions
Postoperative Bacteriuria
Interventions
Straight catheterization, No straight catheterization
Procedure
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Abington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty

NCT03274466
View directory record Official record
Conditions
Surgical Wound, Revision Total Knee Arthroplasty, Wounds and Injuries, Joint Disease, Musculoskeletal Disease, Prosthesis-Related Infections, Infection, Postoperative Complications, Pathologic Processes
Interventions
Closed Incision Negative Pressure Therapy (ciNPT), Standard of Care Dressing
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
22 Years and older
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
17
States / cities
Weston, Florida • Tucker, Georgia • New Orleans, Louisiana + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting No phase listed Observational

Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients

NCT06378359
View directory record Official record
Conditions
Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
Interventions
Screening and decolonization for SA carriers with the 3 drug bundle, No screening for SA, no screening, Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening., Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Enrolling by invitation Phase 4 Interventional

Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee

NCT06636669
View directory record Official record
Conditions
Prosthetic-joint Infection, Dysbiosis
Interventions
Probiotic, Standard of care
Drug · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detection of Staph Colonization in Pre-op Arthroplasty Patients

NCT01648088
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Trial for Postoperative Wound Surveillance Using Smartphones

NCT02735525
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Smartphone monitoring
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 3 Interventional Results available

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

NCT04411199
View directory record Official record
Conditions
Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
Interventions
D-PLEX, Standard of Care (SoC)
Drug · Other
Lead sponsor
PolyPid Ltd.
Industry
Eligibility
18 Years to 99 Years
Enrollment
975 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Augusta, Georgia • New Orleans, Louisiana • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

The Digital Incentive Spirometer (DIS): Improving Adherence to Incentive Spirometry

NCT03686631
View directory record Official record
Conditions
Post-Op Infection, Adherence, Patient, Pulmonary Atelectasis, Incentive Spirometry, Post-Op Complication
Interventions
Smartphone Arm
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

NCT03625011
View directory record Official record
Conditions
Tonsillitis, Tonsillectomy
Interventions
Gabapentin
Drug
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
3 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Zonulin Biomarker for Diagnosis of Hip and Knee Infections

NCT04666519
View directory record Official record
Conditions
Surgical Site Infection, Zonulin
Interventions
Zonulin Biomarker
Diagnostic Test
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 13, 2020 · Synced Sep 25, 2026, 9:10 AM EDT