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ClinicalTrials.gov public records Last synced Jul 21, 2026, 7:41 PM EDT

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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Postoperative Leak Clear all
Completed No phase listed Observational

A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes

NCT06227871
View directory record Official record
Conditions
Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst, Pancreas; Fistula, Pancreas Abscess, Intra-Abdominal Abscess, Anastomotic Leak, Pancreas Injury
Interventions
Exploratory laparotomy
Procedure
Lead sponsor
Kern Medical Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Jul 21, 2026, 7:41 PM EDT
Recruiting No phase listed Observational

Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak

NCT07449208
View directory record Official record
Conditions
Esophageal Malignant Neoplasm Primary, Anastomotic Leak
Interventions
Esophagectomy
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 21, 2026, 7:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

NCT05826743
View directory record Official record
Conditions
Colorectal Surgery, Colorectal Cancer, Rectal/Anal, Ileostomy - Stoma, Anastomotic Leakage
Interventions
COLO BT™, Stoma Creation
Device · Other
Lead sponsor
JSR Medical Co., Ltd.
Industry
Eligibility
19 Years to 80 Years
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Buffalo, New York • Hershey, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 21, 2026, 7:41 PM EDT
Recruiting No phase listed Observational

Endoscopic COlorectal Mucosal Evaluation of Oxygen Tension

NCT07467980
View directory record Official record
Conditions
Anastomotic Leak Rectum, Anastomotic Leak Large Intestine
Interventions
A novel endoscopic imaging system that displays real-time oxygen saturation levels
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 21, 2026, 7:41 PM EDT
Recruiting Not applicable Interventional

Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area

NCT07035431
View directory record Official record
Conditions
Anastomotic Leaks, Hartmanns Stump Leakage
Interventions
Endo-SPONGE
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
9
States / cities
Orlando, Florida • Weston, Florida • Burlington, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 21, 2026, 7:41 PM EDT
Recruiting Not applicable Interventional

Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

NCT07234968
View directory record Official record
Conditions
Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma, Pelvic Malignancy, Bladder Transitional Cell Carcinoma, Bladder Neoplasm
Interventions
Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging
Procedure · Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 21, 2026, 7:41 PM EDT
Enrolling by invitation No phase listed Observational

Endoscopic Metabolic and Bariatric Therapies

NCT05725967
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate, Fistula, Gastric, Roux-en-y Anastomosis Site, Ulcer, Gastric, Abdominal Pain, Abdominal Obesity, Complication of Surgical Procedure, Complication of Treatment, Complication,Postoperative, Weight Gain, Weight Loss, Leak, Anastomotic, Delayed Gastric Emptying Following Procedure
Interventions
Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures, Endoscopic Sleeve Gastroplasty, Trans-oral Outlet Reduction, Intragastric Balloon, Primary obesity surgery endoluminal, Restorative obesity surgery endoluminal, Argon Plasma Coagulation, Gastroplasty with Endoscopic Myotomy, Bariatric Endoscopic Antral Myotomy, Pylorus Sparing Antral Myotomy, Aspiration Therapy
Procedure · Device
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 80 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 21, 2026, 7:41 PM EDT
Withdrawn Phase 2 Interventional

Acetazolamide for the Prevention of Post Operative CSF Leak

NCT04351061
View directory record Official record
Conditions
Cerebrospinal Fluid Leak
Interventions
Acetazolamide
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Jul 21, 2026, 7:41 PM EDT
Completed No phase listed Observational

Observational Analysis of the Cause of Leaks When Bowel is Cut and Reconnected

NCT02178228
View directory record Official record
Conditions
Anastomotic Leaks
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
15 Years and older
Enrollment
1,077 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Jul 21, 2026, 7:41 PM EDT
Completed No phase listed Observational

Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy

NCT01551433
View directory record Official record
Conditions
Esophageal Cancer
Interventions
wireless pulse oximeter (Wipox)
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Jul 21, 2026, 7:41 PM EDT
Not listed Not applicable Interventional

Early Feeding After Oral Cavity Reconstruction

NCT04787939
View directory record Official record
Conditions
Head and Neck Cancer, Free Tissue Transfer
Interventions
Early Feeding
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Jul 21, 2026, 7:41 PM EDT
Withdrawn Not applicable Interventional

Effect of Applying Cuff Air Leak Pressure as Intraoperative Cuff Pressure on Postoperative Complications

NCT04302142
View directory record Official record
Conditions
Intubation Complication
Interventions
ventilation with critical intracuff pressure (Pcr)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Jul 21, 2026, 7:41 PM EDT
Completed Phase 2 Interventional Results available

A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula

NCT03174353
View directory record Official record
Conditions
Pancreatic Leak, Pancreatic Fistula, Pancreaticoduodenal; Fistula, Pancreatectomy; Hyperglycemia
Interventions
Lanreotide Prefilled Syringe
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Jul 21, 2026, 7:41 PM EDT
Completed Not applicable Interventional

A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection

NCT06168669
View directory record Official record
Conditions
Colorectal Surgery, Anastomotic Leak
Interventions
xBar system
Diagnostic Test
Lead sponsor
Exero Medical Ltd.
Industry
Eligibility
22 Years and older
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
10
States / cities
Orlando, Florida • Tampa, Florida • Louisville, Kentucky + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 7:41 PM EDT
Recruiting Not applicable Interventional

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

NCT07351071
View directory record Official record
Conditions
Colorectal Anastomosis, Left-sided Colon Resection, Anastomotic Leak, Anastomotic Complication, Digestive System Diseases, Gastrointestinal Diseases, Colonic Diseases, Intestinal Diseases, Rectal Diseases, Postoperative Complications, Anastomotic Leaks
Interventions
Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system)
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
9
States / cities
New Haven, Connecticut • Tampa, Florida • Boston, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 21, 2026, 7:41 PM EDT
Completed Phase 2 Interventional

Use of NERv's Inline Device as an Early Diagnostic Method for Postoperative Complications

NCT04582708
View directory record Official record
Conditions
Anastomotic Leak, Fistula, Postoperative Leak, Postoperative Pancreatic Fistula, POPF
Interventions
NERv's Inline Device
Device
Lead sponsor
FluidAI Medical
Industry
Eligibility
18 Years and older
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jul 21, 2026, 7:41 PM EDT
Completed Not applicable Interventional

Magnamosis First-in-human Study of Feasibility and Safety

NCT02043392
View directory record Official record
Conditions
Intestinal Anastomosis Complication
Interventions
Magnamosis
Device
Lead sponsor
Michael Harrison
Other
Eligibility
18 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Jul 21, 2026, 7:41 PM EDT
Not listed Phase 3 Interventional

Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing

NCT02907385
View directory record Official record
Conditions
Rectal Cancer, Anastomotic Leak
Interventions
LifeSeal™ Kit
Device
Lead sponsor
LifeBond Ltd.
Industry
Eligibility
21 Years and older
Enrollment
736 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Stanford, California • Florida City, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Jul 21, 2026, 7:41 PM EDT