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ClinicalTrials.gov public records Last synced Nov 9, 2026, 5:21 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 140 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Postoperative Nausea and Vomiting Clear all

Conditions: Nausea and Vomiting, Postoperative
Interventions: GW679769 (casopitant); Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 482 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 26
States / cities: Montgomery, Alabama • Sheffield, Alabama • Phoenix, Arizona + 20 more

Conditions: Postoperative Nausea and Vomiting
Interventions: Palonosetron, Ondansetron, Placebo to Ondansetron, Placebo to Palonosetron; Drug
Lead sponsor: Helsinn Healthcare SA; Industry
Eligibility: Up to 16 Years
Enrollment: 670 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 12
States / cities: Florence, Alabama • Sheffield, Alabama • Washington D.C., District of Columbia + 9 more

Conditions: Post-Operative Nausea and Vomiting
Interventions: granisetron; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 2 Years to 16 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 11
States / cities: Fresno, California • Stanford, California • Hartford, Connecticut + 8 more

Conditions: Postoperative Nausea and Vomiting
Interventions: Not listed
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pain, Postoperative, Postoperative Nausea and Vomiting, Postoperative Hemorrhage, Body Weight Changes
Interventions: Norco (Hydrocodone and Acetaminophen), Percocet (Oxycodone and Acetaminophen), Dilaudid (hydromorphone), Tylenol (Acetaminophen); Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: PONV
Interventions: Aprepitant Injection, Ondansetron (Zofran), Dexamethasone, Placebo; Drug · Other
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years to 90 Years
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Skokie, Illinois

Conditions: Cholecystitis, Acute, Cholelithiasis, Nausea, Postoperative, Vomiting, Postoperative, Pain, Postoperative
Interventions: Acupuncture; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 64 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Bariatric Surgery Candidate, Nausea, Postoperative
Interventions: Peppermint oil aromatherapy; Other
Lead sponsor: Lancaster General Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Lancaster, Pennsylvania

Conditions: Postoperative Nausea and Vomiting
Interventions: granisetron; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 89 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Nausea, Postoperative, Vomiting, Postoperative
Interventions: nausea relief inhaler; Other
Lead sponsor: Methodist Health System; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Mansfield, Texas

Conditions: Postoperative Nausea and Vomiting
Interventions: Not listed
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 17 Years
Enrollment: 193 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Postoperative Pain, Postoperative Nausea and Vomiting, Opioid Use
Interventions: TAP Block, Surgical Site Infiltration, Exparel; Procedure · Drug
Lead sponsor: Danbury Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Danbury, Connecticut

Conditions: Anesthesia, Pediatrics, Surgery
Interventions: regional nerve block, Antiemetic; Procedure · Drug
Lead sponsor: Indiana University; Other
Eligibility: 1 Year to 18 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Postoperative Nausea and Vomiting
Interventions: APD405, Placebo; Drug
Lead sponsor: Acacia Pharma Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 257 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 3
States / cities: San Francisco, California • Durham, North Carolina • Houston, Texas

Conditions: Arthritis Knee, Postoperative Nausea, Postoperative Pain
Interventions: Dexamethasone, Placebo; Drug
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Grosse Pointe Farms, Michigan

Conditions: Postoperative Nausea and Vomiting
Interventions: Olanzapine, Placebo; Drug
Lead sponsor: Jaime B Hyman; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Nausea, Vomiting
Interventions: Dexamethasone, Aprepitant, Placebo Dexamethasone; Drug
Lead sponsor: Main Line Health; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2009
U.S. locations: 1
States / cities: Wynnewood, Pennsylvania

Conditions: Intestinal Pseudo-Obstruction, Manipulation, Osteopathic, Postoperative Care, Postoperative Nausea and Vomiting, Postoperative Complications, Osteopathic Medicine
Interventions: Rib raising and lumbar release, Sham procedure; Procedure
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 69 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Children, Postoperative Pain, Tonsillar Hypertrophy, Obstructive Sleep Apnea, Chronic Tonsillitis
Interventions: Acupuncture, Sham Control; Other
Lead sponsor: Children's ENT of San Diego, Inc.; Other
Eligibility: 2 Years to 17 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: El Centro, California • San Diego, California

Conditions: Nausea, Vomiting, PONV
Interventions: Acupressure Band, Sham Band; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 2 Years to 18 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Pain, Postoperative, Postoperative Nausea and Vomiting
Interventions: Dexamethasone, Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Postoperative Pain
Interventions: Q8003 (morphine sulfate and oxycodone hydrochloride), Morphine sulfate, Oxycodone HCl; Drug
Lead sponsor: QRxPharma Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 4
States / cities: Anaheim, California • Owings Mills, Maryland • Pasadena, Maryland + 1 more

Conditions: Surgical Wound Infection, Surgery, Colon
Interventions: Mild intraoperative hypercapnia (50 mmHg vs. 30 mmHg), Supplemental oxygen (80% vs. 30%), Dexamethasone, Placebo; Other · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2007
U.S. locations: 2
States / cities: Louisville, Kentucky • Cleveland, Ohio

Conditions: Gynecologic Surgical Procedures, Gastric Injury, Aspiration, Nausea, Postoperative, Postoperative Complications, Enhanced Recovery After Surgery, Laparoscopy
Interventions: Gastric decompression (oropharyngeal or nasopharyngeal gastric tube); Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Chicago, Illinois

Search by objective public record fields.

Casopitant (Oral) And ZOFRAN To Prevent Postoperative Nausea And Vomiting In Women

Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric Patients

A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy

Costs of Postoperative Nausea and Vomiting in Ambulatory Surgery Patients

Post-tonsillectomy Pain Control in Adults

Aprepitant to Improve Same Day Discharge for TKA

Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Aromatherapy in Management of Postoperative Nausea in Post-Bariatric Surgery Patients

Granisetron Transdermal Patch for Prevention of Postoperative Nausea and Vomiting

Decreasing Post-Operative Nausea and Vomiting in the Bariatric Surgical Patient

Use of Baxter Animated Retching Faces (BARF) Scale to Measure Nausea in Children Who Speak Spanish

Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision

Comparative Study of Superficial Cervical Plexus Block and Nerve of Arnold Block and Incidence of PONV for Inner Ear Surgery

Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)

Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty

Olanzapine for Nausea After Surgery

Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries

Rib Raising for Post-operative Ileus

Acupuncture for Tonsillectomy Pain

Acupuncture and Acupressure for Postoperative Nausea and Vomiting in Children Undergoing Outpatient Middle Ear Surgery

Dexamethasone for Post-cesarean Delivery Pain

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

The Effects of Hypercapnia, Supplemental Oxygen, and Dexamethasone on Surgical Wound Infection

Surgeon Perception of Gastric Decompression at Time of Gynecologic Laparoscopy