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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Postpartum Psychiatric Disorders Clear all
Completed Not applicable Interventional

Northwell Health Visits: A Family Connects Pilot Implementation at Northwell Health

NCT03887910
View directory record Official record
Conditions
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed, Postpartum Depression
Interventions
Enhanced Intervention, Intervention
Other
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional

Disseminating and Implementing a Smoking Cessation Program for Pregnant and Postpartum Women

NCT02952703
View directory record Official record
Conditions
Smoking, Tobacco Use Disorder
Interventions
brief pre-delivery smoking cessation counseling, additional pre-delivery smoking cessation counseling, post- delivery smoking cessation counseling, incentives
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional

Baby2Home (B2H) Mobile Health Application

NCT05595486
View directory record Official record
Conditions
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness, Post Partum Depression
Interventions
Baby2Home Mobile Application
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yoga in the NICU for Parents Study

NCT05322161
View directory record Official record
Conditions
Postpartum Depression, Anxiety, Depression, Stress Disorder, Prematurity
Interventions
yoga classes
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Not listed
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Doula Support for Young Mothers: A Randomized Trial

NCT01925664
View directory record Official record
Conditions
Parenting, Breastfeeding, Depression, Postpartum
Interventions
Doula
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
14 Years to 21 Years · Female only
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Sep 23, 2026, 3:27 PM EDT
Active, not recruiting Not applicable Interventional

An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers

NCT06054412
View directory record Official record
Conditions
Well-Being, Psychological, Dissociation, Maternal Care Patterns, Maternal Behavior, Maternal Distress, Mood Disturbance, Emotional Regulation, Post Traumatic Stress Disorder
Interventions
Neuroptimal (Zengar, Inc.) Neurofeedback
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Terminated Not applicable Interventional

Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women

NCT04264520
View directory record Official record
Conditions
Perinatal Problems, Post Traumatic Stress Disorder, Post Partum Depression
Interventions
PTSD Psychoeducation + Skills Intervention
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 23, 2026, 3:27 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Is Vitamin D Insufficiency and Deficiency Associated With Antepartum and Postpartum Depression?

NCT02272387
View directory record Official record
Conditions
Depression, Postpartum Depression
Interventions
Vitamin D3 (Cholecalciferol), Placebo
Dietary Supplement · Other
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years and older · Female only
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 23, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional

Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy

NCT07342530
View directory record Official record
Conditions
Written Exposure Therapy, Breathing Techniques, PTSD (Childbirth-Related), Postpartum Care
Interventions
Written Exposure Therapy (WET), Capnometry-Guided Breathing Intervention (CGRI)
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Little Rock, Arkansas • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional

Measuring and Reducing Excessive Infant Crying

NCT01217658
View directory record Official record
Conditions
Infant Colic, Postpartum Depression
Interventions
The Happiest Baby on The Block, AAP Infant Colic counseling
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Weeks to 5 Weeks
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Ketamine to Improve Recovery After Cesarean Delivery - Part 1

NCT04037085
View directory record Official record
Conditions
Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute, Pain, Chronic, Obstetric Anesthesia Problems, Drug Effect, Opioid Use
Interventions
Ketamine
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Sep 23, 2026, 3:27 PM EDT
Active, not recruiting Not applicable Interventional

Living Healthy for Moms RCT

NCT06666400
View directory record Official record
Conditions
Postpartum Depression (PPD), Cardiac Event
Interventions
LHMoms Intervention, No intervention
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Brooklyn, New York • Jamaica, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention

NCT05700760
View directory record Official record
Conditions
Postpartum Depression
Interventions
ROSE (Reach Out, Stay Strong, Essentials for mothers of newborns), Enhanced Care as Usual (CAU)
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older · Female only
Enrollment
2,320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional

OBWELL: Innovative Psychotherapeutic Intervention to Treat Postpartum Depression

NCT06991166
View directory record Official record
Conditions
Post Partum Depression
Interventions
Cognitive behavioral therapy (CBT) psychotherapy group/telehealth, Interpersonal therapy (IPT) psychotherapy group/telehealth
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Terminated Not applicable Interventional

Family Nurture Intervention in the CHoNJ NICU

NCT02352142
View directory record Official record
Conditions
Premature Birth
Interventions
Full Term EEG, Facilitated Infant Care
Other · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 42 Weeks
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Newark, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2016 · Synced Sep 23, 2026, 3:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Maternal Well-Being Study

NCT05484999
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
Interventions
Meals, Meals + Social Support, Control
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Sep 23, 2026, 3:27 PM EDT
Recruiting Phase 3 Interventional

Brexanolone Lifting Outcomes Of Moms

NCT07822321
View directory record Official record
Conditions
Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression, Post-Natal Depression, Peripartum Depression
Interventions
LPCN 1154A, Placebo
Drug
Lead sponsor
Lipocine Inc.
Industry
Eligibility
15 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
16
States / cities
Tucson, Arizona • Canoga Park, California • Walnut Creek, California + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Withdrawn Not applicable Interventional

Preventing Postpartum Depression in Prenatal Care

NCT02741206
View directory record Official record
Conditions
Post-partum Depression
Interventions
Bellevue ROSE Intervention, Psycho-education session and usual, Standard of care Control, One Psycho-education session and usual, standard of care Control
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Perinatal Anal Incontinence Through Early Pelvic Floor Muscle Training: a Prospective Pilot Study

NCT02270008
View directory record Official record
Conditions
Perinatal and Postpartum Anal Incontinence
Interventions
Pelvic floor training
Other
Lead sponsor
Emory University
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression

NCT00602355
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Sertraline, Placebo, Interpersonal psychotherapy (IPT), Clinical management, Mothercrafting
Drug · Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
Iowa City, Iowa • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Sep 23, 2026, 3:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers

NCT05044546
View directory record Official record
Conditions
Depression, Tobacco Use Disorder
Interventions
Behavioral Activation Therapy, Discussion, Health Education, Questionnaire Administration, Tobacco Cessation Counseling
Behavioral · Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 23, 2026, 3:27 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Screening Evaluation for Women With Postpartum Depression

NCT00056901
View directory record Official record
Conditions
Postpartum Depression, Depression
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
20 Years to 45 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)

NCT05907213
View directory record Official record
Conditions
Pain, Postoperative, Depression, Postpartum
Interventions
Ketamine (Ketalar) Dose Level 1, Ketamine (Ketalar) Dose Level 2, Ketamine (Ketalar) Dose Level 3, Ketamine (Ketalar) Dose Level 4
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 23, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood

NCT03646539
View directory record Official record
Conditions
Cognitive Therapy, Depression, Postpartum, Mental Health, Depression, Depressive Disorder, Anxiety, Telemedicine
Interventions
Use of smartphone application (app), Treatment as usual
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2020 · Synced Sep 23, 2026, 3:27 PM EDT