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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Postpartum Psychiatric Disorders Clear all
Recruiting Not applicable Interventional

SAINT in Postpartum Depression (PPD)

NCT07210255
View directory record Official record
Conditions
Postpartum Depression (PPD)
Interventions
SAINT Neuromodulation System, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
4
States / cities
Worcester, Massachusetts • New York, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women

NCT04285684
View directory record Official record
Conditions
Ketamine, Lactation
Interventions
ketamine in lactation
Drug
Lead sponsor
The Ketamine Research Foundation
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Anselmo, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2021 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate Safety and Efficacy of SAGE-547 in Participants With Moderate Postpartum Depression (547-PPD-202C)

NCT02942017
View directory record Official record
Conditions
Postpartum Depression
Interventions
Placebo, SAGE-547 90 μg/kg/h
Drug
Lead sponsor
Supernus Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
32
States / cities
Chandler, Arizona • Rogers, Arkansas • Lemon Grove, California + 28 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jul 23, 2026, 8:19 PM EDT
Recruiting Not applicable Interventional

Substance Use in Pregnant People - Optimizing Retention in Treatment

NCT07104123
View directory record Official record
Conditions
Substance Use Disorder (SUD), Pregnancy, Postpartum, Contingency Management
Interventions
Social drivers of health screening, Patients will undergo a program of contingency management
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months

NCT02221895
View directory record Official record
Conditions
Pregnancy, Breastfeeding, Contraception, Cervical Cancer, Postpartum Depression
Interventions
Postpartum follow up appointment 2-3 weeks after delivery, Postpartum follow up 6-8wk after delivery
Other
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 50 Years · Female only
Enrollment
344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Sep 20, 2020 · Synced Jul 23, 2026, 8:19 PM EDT
Not listed Not applicable Interventional

Translating Research Into Practice for Postpartum Depression

NCT00548743
View directory record Official record
Conditions
Postpartum Depression
Interventions
Screening and follow up, Usual care
Behavioral
Lead sponsor
Olmsted Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 3, 2007 · Synced Jul 23, 2026, 8:19 PM EDT
Recruiting Not applicable Interventional

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

NCT06557005
View directory record Official record
Conditions
Hypertension, Diabetes, Postpartum, Pregnancy, Anxiety, Depression, Obesity
Interventions
Facilitated Transition to Primary Care
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
1,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 23, 2026, 8:19 PM EDT
Completed No phase listed Observational

Prenatal Depression Prevention Effects on Parenting and Young Child Self-Regulation and Functioning

NCT04296734
View directory record Official record
Conditions
Postpartum Depression, Child Development, Parenting, Child Self-Regulation
Interventions
Mothers and Babies
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Months and older
Enrollment
960 participants
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2024 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tracking Depression Symptoms With a Health Chatbot

NCT03990389
View directory record Official record
Conditions
Depression, Postpartum, Depression, Unipolar
Interventions
Chatbot Intervention
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Chicago, Illinois • Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Proyecto BEBE: The Effect of Babywearing Education on Breastfeeding Exclusivity

NCT04376021
View directory record Official record
Conditions
Breastfeeding, Exclusive, Mother-Infant Interaction, Postpartum Depression
Interventions
Babywearing
Behavioral
Lead sponsor
Nurturely
Other
Eligibility
18 Years and older · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Phase 4 Interventional Results available

Escitalopram (Lexapro) for the Treatment of Postpartum Depression

NCT00833469
View directory record Official record
Conditions
Postpartum Depression
Interventions
Escitalopram
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Phase 4 Interventional Results available

Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery

NCT04017442
View directory record Official record
Conditions
Postpartum Pain, Postpartum Depression, Opioid Consumption
Interventions
Preservative Free Morphine, Saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Group Therapy for Postpartum Depression

NCT00051246
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Mother-Infant Group Psychotherapy, Interpersonal Psychotherapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 23, 2014 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cradling Our Future Through Family Strengthening Study

NCT00373750
View directory record Official record
Conditions
Substance Abuse, Post-partum Depression, Depression
Interventions
Family Spirit Intervention
Procedure
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
12 Years to 19 Years · Female only
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
5
States / cities
Fort Defiance, Arizona • San Carlos, Arizona • Tuba City, Arizona + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Growing Together: Women in Opioid Treatment and Their Infants

NCT03866694
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
BRIGHT, STAR/TAU+
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Results available

Mommy-Baby Treatment for Perinatal Depression

NCT01744041
View directory record Official record
Conditions
Depressive Disorder, Major, Postpartum Depression
Interventions
Dyadic Interpersonal Psychotherapy, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Progesterone for Smoking Relapse Prevention Following Delivery

NCT01972464
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Progesterone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Efficacy of Yoga for Postpartum Depression

NCT02213601
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Yoga
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 10, 2014 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Results available

Bridging the Gap From Postpartum to Primary Care

NCT05543265
View directory record Official record
Conditions
Hypertension, Hypertension in Pregnancy, Diabetes Mellitus, Gestational Diabetes, Obesity, Depressive Disorder, Anxiety Disorders
Interventions
Default appointment scheduling, Targeted messaging, Nudge Reminders
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 8:19 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy

NCT03809572
View directory record Official record
Conditions
Maternal Psychological Distress, Postpartum Depression, Prenatal Stress
Interventions
Mindfulness Based Cognitive Therapy
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jul 23, 2026, 8:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers

NCT03638687
View directory record Official record
Conditions
Post Partum Depression, Bipolar Disorder
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Jul 23, 2026, 8:19 PM EDT
Not yet recruiting Not applicable Interventional

Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms

NCT07485036
View directory record Official record
Conditions
Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
Interventions
Contingency Management & Problem Solving Therapy, Usual Care
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Perinatal Depression Treatment in a Pediatric Setting- Pilot Phase

NCT00804739
View directory record Official record
Conditions
Postpartum Depression
Interventions
Mother-Infant Treatment Team
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2012 · Synced Jul 23, 2026, 8:19 PM EDT
Active, not recruiting Not applicable Interventional

Prenatal Yoga to Prevent Postpartum Depression

NCT06004232
View directory record Official record
Conditions
Postpartum Depression
Interventions
Prenatal Yoga to Prevent Postpartum Depression (PRY-D) intervention, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 23, 2026, 8:19 PM EDT