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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Posttraumatic Stress Clear all
Terminated Not applicable Interventional

New Beginnings Following Trauma

NCT05817344
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Opioid Use Disorder
Interventions
Written Exposure Therapy - Integrated
Behavioral
Lead sponsor
Jesse McCann
Other
Eligibility
18 Years to 100 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional

Study to Promote Innovation in Rural Integrated Telepsychiatry

NCT02738944
View directory record Official record
Conditions
Bipolar Disorder, Posttraumatic Stress Disorder
Interventions
Telepsychiatry Collaborative Care, Telepsychiatry Enhanced Referral
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
13
States / cities
Marianna, Arkansas • Marshall, Arkansas • West Memphis, Arkansas + 10 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2020 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)

NCT00984698
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Insomnia Disorder
Interventions
Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 30, 2014 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder

NCT05132699
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
Interventions
Cannabidiol (CBD) oral solution, Placebo, Massed Prolonged Exposure (mPE)
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Treating Co-Morbid Sleep Difficulties in Veterans With Posttraumatic Stress Disorder (PTSD): A Pilot Study

NCT00734799
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia
Interventions
Sleep Intervention for PTSD (SIP).
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
Not listed
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2015 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders

NCT01338506
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
Interventions
Concurrent Treatment with Prolonged Exposure (COPE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders

NCT01631682
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anxiety Disorder
Interventions
Propranolol, Reactivation, Mifepristone, Intranasal oxytocin
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Nepicastat for Posttraumatic Stress Disorder (PTSD) in OIF/OEF Veterans

NCT00659230
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Nepicastat, Placebo
Drug
Lead sponsor
Tuscaloosa Research & Education Advancement Corporation
Other
Eligibility
19 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
3
States / cities
Tuscaloosa, Alabama • San Diego, California • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Mobile Intervention for Veterans With PTSD and Anger

NCT03733028
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anger
Interventions
Mobile Intervention for Reducing Anger (MIRA), Mindfulness Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Enrolling by invitation Not applicable Interventional

Testing STAR and TextSTAR: A Randomized Controlled Trial

NCT07630428
View directory record Official record
Conditions
Sexual Violence, Posttraumatic Stress Disorder (PTSD), Opioid Misuse
Interventions
Skills Training in Active Recovery (STAR) Video, Text Skills Training in Active Recovery (TextSTAR) program
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Louisville, Kentucky • Chapel Hill, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Terminated Phase 2 Interventional Results available

Neurosteroids in PTSD - Biomarkers to Therapeutics

NCT03491007
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
DHEA
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

NCT05843695
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anxiety Disorders
Interventions
iTCBT-I, iTCBT-G, TAU
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Active, not recruiting Not applicable Interventional

Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use

NCT04871100
View directory record Official record
Conditions
Anxiety Disorder, Posttraumatic Stress Disorder, Hazardous Drinking
Interventions
Unified Protocol- Alcohol, Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

NCT02926677
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD

NCT02874131
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Behavioral Activation, Cognitive Processing Therapy
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 4 Interventional

Reducing Cannabis Overuse With Prazosin

NCT04721353
View directory record Official record
Conditions
Cannabis Dependence, Posttraumatic Stress Disorder, Cannabis Use Disorder
Interventions
Prazosin Hydrochloride
Drug
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health

NCT05523453
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Affect, Memory
Interventions
Processing of Positive Memories Technique (PPMT), Supportive Counseling (SC)
Behavioral
Lead sponsor
University of North Texas, Denton, TX
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Denton, Texas
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Neurosensory Account of Anxiety and Stress (Study 2)

NCT07079839
View directory record Official record
Conditions
Threat-related Sensory Cortical (SC) Disinhibition, Posttraumatic Stress Disorder (PTSD)
Interventions
Transcranial Alternating Current Stimulation (tACS), Sham for Transcranial Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional

Integrated Health Care for PTSD

NCT07220681
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Yoga and meditation, Wellness, Positive affect, Information
Behavioral · Other
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
5
States / cities
Little Rock, Arkansas • San Diego, California • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 4 Interventional Results available

Eszopiclone for the Treatment of Posttraumatic Stress Disorder

NCT01605253
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional

Lifespan Integration for Posttraumatic Stress Disorder From an Auto Accident

NCT01263067
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Lifespan Integration Therapy, Lifespan Integration- Control
Behavioral
Lead sponsor
Argosy University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 13, 2015 · Synced Sep 17, 2026, 8:54 AM EDT
Not listed Not applicable Interventional

Addressing Traumatic Stress Symptoms in Children

NCT03334942
View directory record Official record
Conditions
Violence, Non-accidental, Posttraumatic Stress Disorder, Parent-Child Relations, Assault, Youth
Interventions
Child and Family Traumatic Stress Intervention
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional

Impact of Dog Adoption and Training in Veterans With Post-traumatic Stress Symptoms and/or Other Mental Health Conditions

NCT07542431
View directory record Official record
Conditions
Posttraumatic Stress Symptoms, Mental Health Conditions
Interventions
Dog training
Other
Lead sponsor
Florida Atlantic University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional

Web-administered STAIR for Patients on Behavioral Health Waitlists

NCT06431022
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
webSTAIR, CHW coaching
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 17, 2026, 8:54 AM EDT