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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Posttraumatic Stress Disorder Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Inflammation and Threat Sensitivity in PTSD

NCT03048929
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Typhoid Vi Polysaccharide Vaccine, Placebo
Biological
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Sep 28, 2026, 5:58 PM EDT
Recruiting Not applicable Interventional

Evaluating Treatments for Suicidal Veterans With PTSD

NCT05974631
View directory record Official record
Conditions
Self-directed Violence, Post-traumatic Stress Disorder (PTSD)
Interventions
Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol, Prolonged Exposure therapy, Suicide risk management
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Minneapolis, Minnesota • Durham, North Carolina • San Antonio, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional

The Family of Heroes: an Evaluation of an Online Educational Tool

NCT01554839
View directory record Official record
Conditions
Post Traumatic Stress Disorder, PTSD
Interventions
"Family of Heroes", Baseline and Follow up Surveys
Behavioral
Lead sponsor
Department of Veterans Affairs, New Jersey
Federal
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Lyons, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Sep 28, 2026, 5:58 PM EDT
Recruiting Not applicable Interventional

Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)

NCT07410481
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, Cardiac Arrest (CA)
Interventions
Acceptance and Mindfulness Based Exposure Therapy, Present-Centered Therapy
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 81 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Phase 2 Interventional

MDMA for AUD/PTSD Comorbidity

NCT05943665
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
MDMA
Drug
Lead sponsor
Carolina L Haass-Koffler
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Geodon (Ziprasidone) for Posttraumatic Stress Disorder

NCT00208208
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Post-Traumatic Stress Disorder, PTSD
Interventions
Ziprasidone
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 14, 2006 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional Results available

An Adjunctive Family Intervention for Individual Posttraumatic Stress Disorder Treatment

NCT02956434
View directory record Official record
Conditions
Posttraumatic Neuroses
Interventions
Brief Family Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Sep 28, 2026, 5:58 PM EDT
Recruiting Not applicable Interventional

Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

NCT06332209
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Trauma Focused Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
7 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 28, 2026, 5:58 PM EDT
Completed No phase listed Observational

The Trauma Recovery and Resiliency Research Project

NCT00131534
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Individual therapy, Group therapy
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 65 Years
Enrollment
969 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 2012
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 28, 2026, 5:58 PM EDT
Completed No phase listed Observational

The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels

NCT01385709
View directory record Official record
Conditions
Bipolar Affective Disorders, Cyclothymic Disorder, Schizoaffective Disorder, Major Depressive Disorder, Dysthymic Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder, Premenstrual Dysphoric Disorder, Social Anxiety Disorder
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2017 · Synced Sep 28, 2026, 5:58 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

GAMBIT Task With PTSD and Healthy Control Participants

NCT05313334
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
GAMBIT Task
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional

Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms

NCT04776304
View directory record Official record
Conditions
Post-Traumatic Headache, PTSD, TBI, TBI (Traumatic Brain Injury), MTBI - Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, Posttraumatic Stress Disorder, Delayed Onset, Sleep Disturbance, Nightmare, Nightmares, REM-Sleep Type, Headache, Irritable Mood, Anger, Eating Disorders, Combat and Operational Stress Reaction, Combat Stress Disorders, Military Operations, Military Activity, Military Family
Interventions
Art Therapy
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional

Brief Integrative Therapy for Post-Traumatic Stress Disorder

NCT00047684
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Brief Integrative Therapy
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 9, 2013 · Synced Sep 28, 2026, 5:58 PM EDT
Recruiting Not applicable Interventional

Positive Processes and Transition to Health (PATH)

NCT06093906
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Positive Processes and Transition to Health, Progressive Muscle Relaxation
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Newark, Delaware • Cleveland, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans

NCT01510834
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
Interventions
Multibehavioral, Computerized Tailored Intervention STR2IVE
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
3
States / cities
Honolulu, Hawaii • Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Sep 28, 2026, 5:58 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Risk Prediction for Alzheimer Dementia With Brain Imaging and Genetics

NCT03641768
View directory record Official record
Conditions
Alzheimer Dementia, Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
MRI, PET, 18F-Florbetapir, Radioligand 18F-AV-1451
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Phase 2 Interventional Results available

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

NCT01793610
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Comparator Dose (40mg) MDMA HCl, Active Dose 2 (100 mg) MDMA HCl, Active Dose 1 (125 mg) MDMA HCl, Psychotherapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 28, 2026, 5:58 PM EDT
Recruiting Not applicable Interventional

Biomarkers in the Retina for Prognosticating Mental Health Treatments

NCT06363968
View directory record Official record
Conditions
PTSD, Posttraumatic Stress Disorder
Interventions
RETeval
Device
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
21 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Sep 28, 2026, 5:58 PM EDT
Completed No phase listed Observational Results available

Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury

NCT00676182
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Telerehabilitation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Gainesville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional Results available

Messy Memories: Mobile Application Therapy Following Critical Illness

NCT05849454
View directory record Official record
Conditions
Critical Illness, Psychological Distress, Health Behavior
Interventions
Messy Memories Intervention
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 28, 2026, 5:58 PM EDT
Terminated Phase 2 Interventional Results available

Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol

NCT01013870
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Atorvastatin, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2017 · Synced Sep 28, 2026, 5:58 PM EDT
Completed Not applicable Interventional

Client-directed Cognitive Processing Therapy

NCT02684994
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
University of Indianapolis
Other
Eligibility
18 Years and older · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Sep 28, 2026, 5:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

NCT05516277
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
Interventions
Behavioral Sleep Education Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 28, 2026, 5:58 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Developing Anesthesia as Post Traumatic Stress Disorder (PTSD) Therapy

NCT01736020
View directory record Official record
Conditions
Healthy
Interventions
Dexmedetomidine, Propofol, Ketamine, Nitrous Oxide, Placebo
Drug
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years to 35 Years
Enrollment
293 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2017
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2016 · Synced Sep 28, 2026, 5:58 PM EDT