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ClinicalTrials.gov public records Last synced Oct 2, 2026, 9:02 PM EDT

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Showing 73–96 of 1,253 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Posttraumatic Stress Disorder (PTSD) Clear all
Not listed No phase listed Observational

The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure

NCT00631436
View directory record Official record
Conditions
Blast Injuries, Traumatic Brain Injury, Post-Traumatic Stress Disorders
Interventions
Not listed
Lead sponsor
Center for Veterans Research and Education
Other
Eligibility
20 Years to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2011 · Synced Oct 2, 2026, 9:02 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing and Enhancing Social Support

NCT05187156
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Behavioral Activation and Social Engagement, Treatment as usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 2, 2026, 9:02 PM EDT
Recruiting Phase 2 Interventional

HBOT Effects on First Responders' Cognition and Well-Being

NCT07852728
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 2, 2026, 9:02 PM EDT
Recruiting Not applicable Interventional

Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

NCT05786157
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder, Couples
Interventions
Alcohol Administration
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Not applicable Interventional Results available

Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury

NCT03906240
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Moral Injury
Interventions
Moral Elevation intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Oct 2, 2026, 9:02 PM EDT
Active, not recruiting Phase 3 Interventional

A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol

NCT06809218
View directory record Official record
Conditions
Post-Intensive Care Syndrome, Sedation
Interventions
Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
Drug
Lead sponsor
Sedana Medical
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 2, 2026, 9:02 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Enhancing Exposure Therapy for Post-traumatic Stress Disorder

NCT01574118
View directory record Official record
Conditions
Chronic Posttraumatic Stress Disorder
Interventions
Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation, Trauma Memory Retrieval Trial, Exposure to video clips related to the patient's trauma, Breathing retraining, Exposure Homework, Compound extinction
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder

NCT02929979
View directory record Official record
Conditions
Alcohol Use Disorder, PTSD, Cognitive Dysfunction
Interventions
Cognitive Training, Cognitive training placebo control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Not applicable Interventional Results available

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717
View directory record Official record
Conditions
Insomnia, Suicidal Ideation
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Buffalo, New York • Canandaigua, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 2, 2026, 9:02 PM EDT
Completed No phase listed Observational

Improving Brain Stimulation Through Imaging

NCT03851380
View directory record Official record
Conditions
Depression, Depressive Disorder, Treatment-Resistant, COVID Stress, PTSD - Post Traumatic Stress Disorder
Interventions
Psychological / Functional Assessment, Structural and Functional MRI, Transcranial Magnetic Brain Stimulation and MR Image Guidance, Transcranial Electrical Stimulation (tES)
Behavioral · Other · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 2, 2026, 9:02 PM EDT
Completed No phase listed Observational

Patient Participation Beliefs and Post-Traumatic Stress Disorder (PTSD)

NCT01419223
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Brain Injuries, Traumatic
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2013 · Synced Oct 2, 2026, 9:02 PM EDT
Recruiting Not applicable Interventional

Evaluating Evidenced Based Options for PTSD Treatment

NCT06733376
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy, Prolonged Exposure, Skills Training for Affective and Interpersonal Regulation
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study to Assess the Use of Methylone in the Treatment of PTSD

NCT05741710
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Methylone, Placebo
Drug
Lead sponsor
Transcend Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
Denver, Colorado • Jacksonville, Florida • Maitland, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 2, 2026, 9:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Nerve Stimulation for PTSD and Sleep

NCT03170440
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcutaneous nerve stimulation location 1
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 55 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Not applicable Interventional

Treatment of Post Traumatic Stress Disorder in Patients With Other Mental Illnesses

NCT00053690
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive Behavior Treatment
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Claremont, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 10, 2013 · Synced Oct 2, 2026, 9:02 PM EDT
Not listed Not applicable Interventional

Trauma-Focused Cognitive Behavior Therapy for Youth: Effectiveness in a Community Setting

NCT01649141
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Trauma-Focused Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Delaware Division of Prevention and Behavioral Health Services
Government
Eligibility
7 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 25, 2012 · Synced Oct 2, 2026, 9:02 PM EDT
Terminated Phase 3 Interventional

Helping Children With Trauma

NCT02737488
View directory record Official record
Conditions
Trauma, Post-Traumatic Stress Disorder
Interventions
Trauma Systems Therapy (TST), Treatment as Usual (TAU)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
7 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Phase 2 Interventional

Body-Oriented Therapy for Sexual Abuse Recovery

NCT00097305
View directory record Official record
Conditions
Child Abuse, Sexual, Post-Traumatic Stress Disorder, Dissociation
Interventions
Body-Oriented Therapy, Standardized Massage Therapy
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
25 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 11, 2007 · Synced Oct 2, 2026, 9:02 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Mental Health in Veterans and Families After Group Therapies

NCT01327690
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
CBT (Cognitive Behavior Therapy), EFT (Emotional Freedom Techniques)
Behavioral
Lead sponsor
Soul Medicine Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2027
U.S. locations
1
States / cities
Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Not applicable Interventional

Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence

NCT00923923
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Alcohol Dependence
Interventions
stress
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Oct 2, 2026, 9:02 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women

NCT00032617
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure, Present Centered Therapy
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Female only
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
13
States / cities
Denver, Colorado • Bay Pines, Florida • Decatur, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2010 · Synced Oct 2, 2026, 9:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Neurobiological Similarities of Tinnitus and PTSD

NCT05981391
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Tinnitus
Interventions
resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry, Tinnitus Assessment, Otoscopy, Pure tone air and bone-conduction, Speech testing, Loudness Discomfort, Quick Speech in Noise Test, Distortion-Product Otoacoustic Emissions (DPOAE)
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 2, 2026, 9:02 PM EDT
Terminated Phase 4 Interventional Results available

PTSD Symptom Reduction by Propranolol Given After Trauma Memory Activation

NCT00645450
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Propranolol, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 2, 2026, 9:02 PM EDT
Recruiting Not applicable Interventional

Restorative Early Sleep Treatment After the Emergency Department

NCT07121270
View directory record Official record
Conditions
Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education, Sleep Education enhanced with Nightmare Education
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 2, 2026, 9:02 PM EDT